1,3,5-tri-O-allyl-scyllo-inositol | 865837-93-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3,5-tri-O-allyl-scyllo-inositol
• CAS: 865837-93-0
• 化学式: C₁₅H₂₄O₆
• 分子量: 300.352
• InChiKey: UHEWGVHRSBQHND-WATWQVSESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  21.0
• 可旋转键数：
  9.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  88.38
• 氢给体数：
  3.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  1,3,5-tri-O-allyl-scyllo-inositol 在 sodium azide 、 对甲苯磺酸 、 三苯基膦 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 22.0h， 生成 2,4,6-tri-O-allyl-scyllo-inositol 4-aminoorthobutyrate
  参考文献：
  名称：

  Syntheses of glycodendrimers having scyllo-inositol as the scaffold

  摘要：

  Synthetic glycoconjugated dendrimers have emerged as important functional glycomimetics for studying multivalency effects in the cell-cell communications. We report herein, a synthetic route to functionalized glycodendrimers with scyllo-inositol as the scaffold, which have a directed geometry; one side of the dendrimers is designed for ready attachment to the AFM probe/solid matrix, and the other to have a varying number of a sugar. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.001
• 作为产物：
  描述：

  4,6-di-O-allyl-scyllo-inositol 1,3,5-O-orthoformate 在 sodium hydride 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 甲醇 、 乙酸乙酯 为溶剂， 反应 3.33h， 生成 1,3,5-tri-O-allyl-scyllo-inositol
  参考文献：
  名称：

  Syntheses of glycodendrimers having scyllo-inositol as the scaffold

  摘要：

  Synthetic glycoconjugated dendrimers have emerged as important functional glycomimetics for studying multivalency effects in the cell-cell communications. We report herein, a synthetic route to functionalized glycodendrimers with scyllo-inositol as the scaffold, which have a directed geometry; one side of the dendrimers is designed for ready attachment to the AFM probe/solid matrix, and the other to have a varying number of a sugar. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.001