1,2-bis-benzyloxy-3-methoxy-benzene | 55020-67-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,2-bis-benzyloxy-3-methoxy-benzene
• 英文别名: 1,2-Bis-benzyloxy-3-methoxy-benzol；1-Methoxy-2,3-bis(phenylmethoxy)benzene
• CAS: 55020-67-2
• 化学式: C₂₁H₂₀O₃
• 分子量: 320.388
• InChiKey: QSWDZHBUTPSWLD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,2-bis-benzyloxy-3-methoxy-benzene 在 乙醇 、 硫酸 、 硝酸 、 溶剂黄146 、 锌 作用下， 生成 2-benzyloxy-6-methoxy-hydroquinone
  参考文献：
  名称：

  King et al., Journal of the Chemical Society, 1954, p. 4594,4599

  摘要：

  DOI：
• 作为产物：
  描述：

  3-甲氧基儿茶酚 、 溴甲苯 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以91%的产率得到1,2-bis-benzyloxy-3-methoxy-benzene
  参考文献：
  名称：

  仿生方法对丙烯醛酸的吡啶酮环：丙烯醛酸A的简明合成和丙烯醛酸B的方法

  摘要：

  描述了丙烯醛酸A 1，别甲丙酸A 19的合成和制备丙烯醛酸B 2的方法。钯（0）催化的交叉偶联反应用于生成C-4邻苯二酚前体，并使用仿生氧化裂解-循环化策略研究了吡啶酮环的形成。

  DOI：

  10.1016/s0040-4020(98)00377-9

文献信息

• HUMAN PLASMA KALLIKREIN INHIBITORS
  申请人：BIOCRYST PHARMACEUTICALS, INC.

  公开号：US20170073314A1

  公开（公告）日：2017-03-16

  Disclosed are compounds of formula I as described herein, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also disclosed are pharmaceutical compositions comprising at least one such compound, and methods involving use of the compounds and compositions in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.
• ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20170336728A1

  公开（公告）日：2017-11-23

  An object of the present invention is to provide an ultraviolet curing liquid composition having high sensitivity, excellent storage stability, low viscosity, and excellent fixability after ultraviolet curing. The ultraviolet curable liquid composition of the present invention is an ultraviolet curable liquid composition containing a cationically polymerizable liquid monomer, a photopolymerization initiator and a photopolymerization sensitizer, wherein the cationically polymerizable liquid monomer is a vinyl ether compound, the photopolymerization initiator includes a compound represented by general formula (1), and the photopolymerization sensitizer includes (A) at least one compound selected from the group consisting of a compound represented by general formula (2) and a compound represented by general formula (3), and (B) at least one compound selected from the group consisting of a compound represented by general formula (4) and a compound represented by general formula (5).