甲基4,6-O-[(4-甲氧基苯基)亚甲基]-2,3-二-O-(苯基甲基)-ALPHA-D-吡喃半乳糖苷 | 94902-59-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃二恶英
• 中文名称: 甲基4,6-O-[(4-甲氧基苯基)亚甲基]-2,3-二-O-(苯基甲基)-ALPHA-D-吡喃半乳糖苷
• 英文名称: methyl 2,3-di-O-benzyl-4,6-O-(4-methoxybenzylidene)-α-D-galactopyranoside
• 英文别名: methyl 2,3-di-O-benzyl-4,6-O-((4-methoxyphenyl)methylene)-α-D-galactopyranoside；Methyl 2,3-DI-O-benzyl-4,6-O-(4-methoxybenzylidene)-A-D-galactopyranoside；(4aR,6S,7R,8S,8aS)-6-methoxy-2-(4-methoxyphenyl)-7,8-bis(phenylmethoxy)-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine
• CAS: 94902-59-7
• 化学式: C₂₉H₃₂O₇
• 分子量: 492.569
• InChiKey: DHAREFMCLBQPOA-ZIFDVUIGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  甲基4,6-O-[(4-甲氧基苯基)亚甲基]-2,3-二-O-(苯基甲基)-ALPHA-D-吡喃半乳糖苷 在 硼烷四氢呋喃络合物 、 2,2,6,6-四甲基哌啶氧化物 、 碘苯二乙酸 、 四丁基碘化铵 、 potassium hydrogencarbonate 作用下， 以 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 12.25h， 生成 methyl (methyl 2,3-di-O-benzyl-α-D-galactopyranosid)uronate
  参考文献：
  名称：

  Synthesis of oligosaccharide fragments of the rhamnogalacturonan of Nerium indicum

  摘要：

  Three trisaccharides, one pentasaccharide, and one heptasaccharide, namely alpha-D-GalA-(1 -> 2)-alpha-L-Rha(1 -> 4)-beta-D-GalA-OC3H7 (1), alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 4)-beta-D-GalA-OC3H7 (2), alpha-D-GalA-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-OC3H7 (3), alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-beta-D-GalA-OC3H7 (4), and alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-beta-D-GalA-OC3H7 (5), which are relevant to the fragments of the rhamnogalacturonan of Nerium indicum, were concisely synthesized. The syntheses feature highly stereoselective formation of the alpha-D-GalA-linkage with GalA N-phenyltrifluoroacetimidates as donors. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2013.05.008
• 作为产物：
  描述：

  4-甲氧基苯甲醛二甲缩醛 在 sodium hydride 、 对甲苯磺酸 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 生成 甲基4,6-O-[(4-甲氧基苯基)亚甲基]-2,3-二-O-(苯基甲基)-ALPHA-D-吡喃半乳糖苷
  参考文献：
  名称：

  Johansson, Rolf; Samuelsson, Bertil, Journal of the Chemical Society. Perkin transactions I, 1984, p. 2371 - 2374

  摘要：

  DOI：

文献信息

• Synthesis of oligosaccharide fragments of the rhamnogalacturonan of Nerium indicum
  作者：Yuyong Ma、Xin Cao、Biao Yu

  DOI：10.1016/j.carres.2013.05.008

  日期：2013.8

  Three trisaccharides, one pentasaccharide, and one heptasaccharide, namely alpha-D-GalA-(1 -> 2)-alpha-L-Rha(1 -> 4)-beta-D-GalA-OC3H7 (1), alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 4)-beta-D-GalA-OC3H7 (2), alpha-D-GalA-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-OC3H7 (3), alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-beta-D-GalA-OC3H7 (4), and alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-alpha-D-GalA-(1 -> 2)-alpha-L-Rha-(1 -> 4)-beta-D-GalA-OC3H7 (5), which are relevant to the fragments of the rhamnogalacturonan of Nerium indicum, were concisely synthesized. The syntheses feature highly stereoselective formation of the alpha-D-GalA-linkage with GalA N-phenyltrifluoroacetimidates as donors. (c) 2013 Elsevier Ltd. All rights reserved.
• Johansson, Rolf; Samuelsson, Bertil, Journal of the Chemical Society. Perkin transactions I, 1984, p. 2371 - 2374
  作者：Johansson, Rolf、Samuelsson, Bertil

  DOI：——

  日期：——