2-(2-叔丁基-4-甲基苯氧基)苯乙酮 | 1023755-95-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-(2-叔丁基-4-甲基苯氧基)苯乙酮
• 英文名称: 2-(2-tert-butyl-4-methylphenoxy)-acetophenone
• 英文别名: 2-(2-Tert-butyl-4-methylphenoxy)-1-phenylethanone
• CAS: 1023755-95-4
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.382
• InChiKey: FJNCFNLJDRULHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(2-叔丁基-4-甲基苯氧基)苯乙酮 在 sodium hydroxide 、 异丙醇 作用下， 反应 2.0h， 以97%的产率得到2-(2-tert-butyl-4-methylphenoxy)-1-phenylethanol
  参考文献：
  名称：

  Biomimetic transfer hydrogenation of 2-alkoxy- and 2-aryloxyketones with iron–porphyrin catalysts

  摘要：

  In situ generated iron porphyrins are applied as homogeneous catalysts in the transfer hydrogenation of a-substituted ketones. Using 2-propanol as hydrogen donor various protected 1, 2-hydroxyketones are reduced to the corresponding mono-substituted 1,2-diols in good to excellent yield. Under optimized reaction conditions catalyst turnover frequencies up to 2500 h(-1) have been achieved. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.01.083
• 作为产物：
  描述：

  叔-丁基对甲酚 、 2-溴苯乙酮 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 12.0h， 以44%的产率得到2-(2-叔丁基-4-甲基苯氧基)苯乙酮
  参考文献：
  名称：

  Biomimetic transfer hydrogenation of 2-alkoxy- and 2-aryloxyketones with iron–porphyrin catalysts

  摘要：

  In situ generated iron porphyrins are applied as homogeneous catalysts in the transfer hydrogenation of a-substituted ketones. Using 2-propanol as hydrogen donor various protected 1, 2-hydroxyketones are reduced to the corresponding mono-substituted 1,2-diols in good to excellent yield. Under optimized reaction conditions catalyst turnover frequencies up to 2500 h(-1) have been achieved. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.01.083

文献信息

• Employing Cu(II) complexes of N,O-donor ligand for catalysis in visible light driven cleavage of lignin C-C bonds
  作者：Rishi Ranjan、Argha Chakraborty、Rakesh Ganguly、Suman Mukhopadhyay

  DOI：10.1016/j.mcat.2023.112947

  日期：2023.2

  [CuL(N3)]2 (2) have been obtained by reacting HL with Cu(II) salts. Under visible light irradiation, these catalysts can cleave the CC bonds of lignin in H2O as suggested by HPLC data. After completion of the reaction, the photo-catalysts could be recovered almost quantitatively and recycled for at least six times without much decrease in the catalytic efficiency. A plausible mechanistic pathway for the

  过渡金属配合物催化的可见光辅助光反应最近对环境友好的可持续过程的发展有着巨大的需求。为了开发潜在的含铜光催化剂，席夫碱配体即。合成并表征了2-[((3-(二甲基氨基)-2,2-二甲基丙基)亚氨基)(苯基)甲基]苯酚(HL) 。HL与Cu(II)盐反应得到了两个双核铜配合物[Cu(L)Cl] 2 ( 1 ) 和[CuL(N 3 )] 2 ( 2 )。在可见光照射下，这些催化剂可以裂解H 2中木质素的CC键O 如 HPLC 数据所示。反应完成后，光催化剂几乎可以定量回收并循环使用至少六次，而催化效率没有太大下降。通过 ESI-MS 光谱、NMR 光谱、UV-vis 和计算研究探索了降解反应的可能机制途径。光催化剂可以将高达 95% 的真实提取木质纤维素样品降解为有价值的化学物质。这些催化剂已显示出对阳光以及木质素降解的活性。
• Biomimetic transfer hydrogenation of 2-alkoxy- and 2-aryloxyketones with iron–porphyrin catalysts
  作者：Stephan Enthaler、Björn Spilker、Giulia Erre、Kathrin Junge、Man Kin Tse、Matthias Beller

  DOI：10.1016/j.tet.2008.01.083

  日期：2008.4

  In situ generated iron porphyrins are applied as homogeneous catalysts in the transfer hydrogenation of a-substituted ketones. Using 2-propanol as hydrogen donor various protected 1, 2-hydroxyketones are reduced to the corresponding mono-substituted 1,2-diols in good to excellent yield. Under optimized reaction conditions catalyst turnover frequencies up to 2500 h(-1) have been achieved. (c) 2008 Elsevier Ltd. All rights reserved.