1-methyl-2,3,4-tri-O-benzyl-β-D-glucopyrano-2(Z)-butene-5,5'-dione | 1400906-98-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-methyl-2,3,4-tri-O-benzyl-β-D-glucopyrano-2(Z)-butene-5,5'-dione
• 英文别名: (Z)-1,4-bis[(2S,3S,4S,5R,6S)-6-methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]but-2-ene-1,4-dione
• CAS: 1400906-98-0
• 化学式: C₅₈H₆₀O₁₂
• 分子量: 949.107
• InChiKey: IDIQVGLVNDFXES-ZQJNAQQPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  70
• 可旋转键数：
  24
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  126
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  1-methyl-2,3,4-tri-O-benzyl-7-deoxy-7-diazo-α-D-glucoheptopyran-6-ulose 在 copper acetylacetonate 作用下， 以 二氯甲烷 为溶剂， 反应 0.08h， 生成 1-methyl-2,3,4-tri-O-benzyl-β-D-glucopyrano-2(Z)-butene-5,5'-dione 、 1-methyl-2,3,4-tri-O-benzyl-β-D-glucopyrano-2(E)-butene-5,5'-dione
  参考文献：
  名称：

  Study on Metal-Induced Reactions of α-Diazocarbonyl Glucosides

  摘要：

  Conversions of diazocarbonyl carbohydrate compounds catalyzed by a series of rhodium and copper catalysts in conventional heating or microwave conditions were investigated. C-H insertion product was obtained in the presence of Rh-2(OAc)(4). Intermolecular reactions rather than intramolecular reactions occurred in the presence of copper catalysts.

  DOI：

  10.1021/jo300986c

文献信息

• Study on Metal-Induced Reactions of α-Diazocarbonyl Glucosides
  作者：Zhu Guan、Li-He Zhang、Pierre Sinaÿ、Yongmin Zhang

  DOI：10.1021/jo300986c

  日期：2012.10.19

  Conversions of diazocarbonyl carbohydrate compounds catalyzed by a series of rhodium and copper catalysts in conventional heating or microwave conditions were investigated. C-H insertion product was obtained in the presence of Rh-2(OAc)(4). Intermolecular reactions rather than intramolecular reactions occurred in the presence of copper catalysts.