ethyl 3,7,11,15-tetramethylhexadecanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: ethyl 3,7,11,15-tetramethylhexadecanoate
• 英文别名: 3,7,11,15-tetramethyl-hexadecanoic acid ethyl ester
• 化学式: C₂₂H₄₄O₂
• 分子量: 340.59
• InChiKey: RDNOHEMCCBNRKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  24
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  ethyl (2Z,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenoate 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 为溶剂， 以96%的产率得到ethyl 3,7,11,15-tetramethylhexadecanoate
  参考文献：
  名称：

  Odinokov, V. N.; Kukovinets, O. S.; Sakharova, N. I., Russian Journal of Organic Chemistry, 1993, vol. 29, # 1.1, p. 24 - 30

  摘要：

  DOI：

文献信息

• Topical agent containing phytanic acid or a derivative thereof
  申请人：Vollhardt Herber Jurgen

  公开号：US20060165637A1

  公开（公告）日：2006-07-27

  The invention relates to agents for topical administration of a compound of formula (I): (CH 3 ) 2 CH—(CH 2 ) 3 —CH(CH 3 )—(CH 2 ) 3 —CH(CH 3 )—(CH 2 ) 3 —C(A)(CH 3 )—C(B) 2 —C(O)—R, wherein R represents hydrogen, OR 1 , N(OH)R 1 or NR 2 R 3 ; R 1 , R 2 and R 3 independently represent hydrogen C 1 -C 22 -alkyl, C 1 -C 22 -alkenyl, C 7 -C 12 -arylalkyl (particularly benzyl, phenethyl and phenylpropyl), retinyl, tocopheryl, ascorbyl or a radical stemming from an amino acid or a peptide and A and B represent hydrogen atoms or A and a radical B form a double bond and the other radical B represents a hydrogen atom or radical A represents a hydrogen atom and the radicals B together form an oxygen atom or one of the radicals B represents a hydroxyl group and the other radical B and radical A represent hydrogen atoms. Said agents contain a compound of formula (I) and a pharmaceutically and/or cosmetically acceptable carrier provided that the agent does not contain any retinoids.

  本发明涉及一种用于局部给药化合物的代理人，其化学式为（I）：（CH3）2CH-（CH2）3-CH（CH3）-（CH2）3-CH（CH3）-（CH2）3-C（A）（CH3）-C（B）2-C（O）-R，其中R代表氢，OR1，N（OH）R1或NR2R3；R1，R2和R3分别独立地代表氢，C1-C22-烷基，C1-C22-烯基，C7-C12-芳基烷基（特别是苄基，苯乙基和苯丙基），视黄醇，生育酚，抗坏血酸或来自氨基酸或肽的基团，A和B代表氢原子或A和基团B形成双键，另一个基团B代表氢原子，或基团A代表氢原子，基团B一起形成氧原子，或其中一个基团B代表羟基，另一个基团B和基团A代表氢原子。所述代理人包含化合物（I）和一种药学和/或化妆品上可接受的载体，但该代理人不含任何视黄醇。
• Purified compositions of polyunsaturated fatty acids, their preparation method and their use
  申请人：Bruzzese Tiberio

  公开号：US10821090B2

  公开（公告）日：2020-11-03

  The present invention refers to new purified compositions of long chain polyunsaturated fatty acids, or their salts or esters, characterized by being essentially free from other usually present—but structurally different—components, such as furan fatty acids, phytanic and pristanic acids, squalene, and some oligomers, as well as several “persistent” environmental pollutants, such as polychlorinated dibenzo-dioxins and polychlorinated dibenzo-furans, polychlorinated biphenyls, polybrominated diphenyl-ethers, polycyclic aromatic hydrocarbons, and others, which are also usually present and extremely toxic. The invention also refers to the purification method to obtain said compositions and the use thereof as food, food for special medical use, food and diet supplement, and drug.

  本发明指的是长链多不饱和脂肪酸或其盐或酯的新的纯化组合物，其特征是基本上不含其他通常存在但结构不同的成分，如呋喃脂肪酸、植酸和肉苁蓉酸、角鲨烯和一些低聚物，以及几种 "持久性 "环境污染物，如多氯化二苯并二噁英和多氯化二苯并呋喃、多氯联苯、和一些低聚物，以及几种 "持久性 "环境污染物，例如多氯二苯并二噁英和多氯二苯并呋喃、多氯联苯、多溴联苯醚、多环芳烃等，它们通常也存在且毒性极强。本发明还涉及获得所述组合物的提纯方法及其作为食品、特殊医用食品、食品和膳食补充剂以及药物的用途。
• AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS
  申请人：Biovitrum AB (publ)

  公开号：EP2004159A1

  公开（公告）日：2008-12-24
• PURIFIED COMPOSITIONS OF POLYUNSATURATED FATTY ACIDS, THEIR PREPARATION METHOD AND THEIR USE
  申请人：Bruzzese, Tiberio

  公开号：EP3273954B1

  公开（公告）日：2020-10-28
• Autoimmune conditions and NADPH oxidase defects
  申请人：Linschoten Marcel

  公开号：US20080051451A1

  公开（公告）日：2008-02-28

  The invention relates to methods and materials involved in treating autoimmune conditions. In particular, the invention relates to methods and compounds (and compositions including the compounds) involved in treating, preventing, or delaying the onset of autoimmune conditions. The compounds include one or more isoprenoid units. The compounds can enhance NADPH oxidase activity.