5-methyl-4-(6-phenanthridinylmethoxy)-1-hexanol | 146174-75-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 5-methyl-4-(6-phenanthridinylmethoxy)-1-hexanol
• 英文别名: 5-Methyl-4-(phenanthridin-6-ylmethoxy)hexan-1-ol
• CAS: 146174-75-6
• 化学式: C₂₁H₂₅NO₂
• 分子量: 323.435
• InChiKey: ZOLFNUCQVJXSND-UHFFFAOYSA-N

物化性质

• 沸点：
  484.3±30.0 °C(Predicted)
• 密度：
  1.125±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  42.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-methyl-4-(6-phenanthridinylmethoxy)-1-hexanol 以 乙腈 为溶剂， 以66%的产率得到6-hydroxy-2-methyl-hexan-3-one
  参考文献：
  名称：

  Photolytic generation of ketones from 6-phenanthridinylmethyl ethers of secondary alcohols

  摘要：

  Ketones are generated by photolysis (> 320 nm) of 6-phenanthridinylmethyl ethers of secondary alcohols. The 6-phenanthridinylmethyl group may therefore be utilized as a latent carbonyl function, especially as the 6-phenanthridinyl-methyl group is chemically inert toward hydroboration, Grignard additions, LiAlH4-reduction, bromination or ozonolysis at other parts of the molecule.

  DOI：

  10.1016/s0040-4020(01)88353-8
• 作为产物：
  描述：

  6-(溴甲基)菲啶 在 sodium tetrahydroborate 、 sodium hydride 、 臭氧 、 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 生成 5-methyl-4-(6-phenanthridinylmethoxy)-1-hexanol
  参考文献：
  名称：

  Photolytic generation of ketones from 6-phenanthridinylmethyl ethers of secondary alcohols

  摘要：

  Ketones are generated by photolysis (> 320 nm) of 6-phenanthridinylmethyl ethers of secondary alcohols. The 6-phenanthridinylmethyl group may therefore be utilized as a latent carbonyl function, especially as the 6-phenanthridinyl-methyl group is chemically inert toward hydroboration, Grignard additions, LiAlH4-reduction, bromination or ozonolysis at other parts of the molecule.

  DOI：

  10.1016/s0040-4020(01)88353-8

文献信息

• Photolytic generation of ketones from 6-phenanthridinylmethyl ethers of secondary alcohols
  作者：Vatcharin Rukachaisirikul、Reinhard W. Hoffmann

  DOI：10.1016/s0040-4020(01)88353-8

  日期：1992.11

  Ketones are generated by photolysis (> 320 nm) of 6-phenanthridinylmethyl ethers of secondary alcohols. The 6-phenanthridinylmethyl group may therefore be utilized as a latent carbonyl function, especially as the 6-phenanthridinyl-methyl group is chemically inert toward hydroboration, Grignard additions, LiAlH4-reduction, bromination or ozonolysis at other parts of the molecule.