2-(2,4,6-trichlorophenyl)-4-formyl-1,2,3-triazole oxime | 89522-35-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2,4,6-trichlorophenyl)-4-formyl-1,2,3-triazole oxime
• CAS: 89522-35-0
• 化学式: C₉H₅Cl₃N₄O
• 分子量: 291.524
• InChiKey: BTVRPRCJPNASEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.04
• 重原子数：
  17.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.3
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  2-(2,4,6-trichlorophenyl)-4-formyl-1,2,3-triazole oxime 在 三聚甲醛 、 盐酸 作用下， 反应 6.0h， 生成 2-(2,4,6-trichlorophenyl)-4-formyl-1,2,3-triazole
  参考文献：
  名称：

  The Synthesis and Insecticidal Activity of a Series of 2‐Aryl‐1,2,3‐triazoles

  摘要：

  Two synthetic routes to 2-aryl-1,2,3-triazoles are outlined. These have been used to synthesise a wide range of compounds of this structural type. Their insecticidal activities were evaluated against a number of veterinary and public health pests. The activity of these compounds is especially good against the housefly (Musca domestica). Structure-activity relationships are discussed particularly in relation to the physical properties of the compounds.

  DOI：

  10.1002/(sici)1096-9063(199610)48:2<189::aid-ps461>3.0.co;2-#
• 作为产物：
  描述：

  mesoaldehyde 1,3-dioxime-2-(2,4,6-trichlorophenyl)hydrazone 在 caesium carbonate 、 溶剂黄146 作用下， 以 四氢呋喃 为溶剂， 反应 1.75h， 生成 2-(2,4,6-trichlorophenyl)-4-formyl-1,2,3-triazole oxime
  参考文献：
  名称：

  The Synthesis and Insecticidal Activity of a Series of 2‐Aryl‐1,2,3‐triazoles

  摘要：

  Two synthetic routes to 2-aryl-1,2,3-triazoles are outlined. These have been used to synthesise a wide range of compounds of this structural type. Their insecticidal activities were evaluated against a number of veterinary and public health pests. The activity of these compounds is especially good against the housefly (Musca domestica). Structure-activity relationships are discussed particularly in relation to the physical properties of the compounds.

  DOI：

  10.1002/(sici)1096-9063(199610)48:2<189::aid-ps461>3.0.co;2-#

文献信息

• Swartz, David L.; Karash, Angela R.; Berry, Laura A., Journal of Heterocyclic Chemistry, 1983, vol. 20, p. 1561 - 1564
  作者：Swartz, David L.、Karash, Angela R.、Berry, Laura A.、Jaeger, David L.

  DOI：——

  日期：——