methyl 8-methylquinoline-3-carboxylate | 1398505-07-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: methyl 8-methylquinoline-3-carboxylate
• CAS: 1398505-07-1
• 化学式: C₁₂H₁₁NO₂
• 分子量: 201.225
• InChiKey: JVBFZMFGINGTOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  tert-butyl propyl-2-yn-1-yl(o-tolyl)carbamate 在 palladium(II) trifluoroacetate 、 (S,S)-2,2'-异亚丙基双(4-苯基-2-恶唑啉) 、 三氟乙酸 、 对苯醌 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 methyl 8-methylquinoline-3-carboxylate 、 bis(8-methylquinolin-3-yl)methanone
  参考文献：
  名称：

  N-炔丙基苯胺和邻炔基苯酚与钯（II）-双异恶唑啉催化剂的环化-羰基化-环化偶联反应

  摘要：

  摘要 （盒）Pd（II）配合物催化的N-炔丙基苯胺和邻炔基苯酚的环化-羰基化-环化偶联反应（CCC偶联反应）得到对称的双（喹啉-3-基）和双（苯并呋喃-3-基）酮，分别以中等至优异的产率。 （盒）Pd（II）配合物催化的N-炔丙基苯胺和邻炔基苯酚的环化-羰基化-环化偶联反应（CCC偶联反应）得到对称的双（喹啉-3-基）和双（苯并呋喃-3-基）酮，分别以中等至优异的产率。

  DOI：

  10.1055/s-0031-1290805

文献信息

• Polythiophene-Encapsulated Bimetallic Au-Fe₃O₄ Nano-Hybrid Materials: A Potential Tandem Photocatalytic System for Nondirected C(sp²)–H Activation for the Synthesis of Quinoline Carboxylates
  作者：Mandeep Kaur、Subhamay Pramanik、Manoj Kumar、Vandana Bhalla

  DOI：10.1021/acscatal.6b02681

  日期：2017.3.3

  Hetero-oligophenylene derivative 3 appended with thiophene moieties has been designed and synthesized which undergoes aggregation to form J-typefluorescent aggregates in in H2O/THF (7/3) media. These aggregates served as reactors for the preparation of bimetallic Au-Fe3O4 NPs. During the reduction process, aggregates of derivative 3 were oxidized to the polythiophene species 4. Interestingly, the polythiophene species 4, having a fibrous morphology, served as a shape-and morphology-directed template for assembly of bimetallic Au-Fe3O4 NPs in a flower-like arrangement. Furthermore, polythiophene-encapsulated bimetallic 4:AuFe3O4 nanohybrid materials served as an efficient and recyclable catalytic system for C(sp(2)) H bond activation of unprotected electron-rich anilines for the construction of synthetically versatile quinoline carboxylates via C H activation, carbonylation, and subsequent annulation under mild and eco-friendly conditions (aqueous media, room temperature, visible-light irradiation, and aerial conditions).