3β,16β-bis-formyloxy-olean-12-ene | 64181-08-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3β,16β-bis-formyloxy-olean-12-ene
• 英文别名: 3β,16β-Bis-formyloxy-olean-12-en；Di-O-formyl-maniladiol；(4aS)-5c.10c-Diformyloxy-2.2.4ar.6at.6bc.9.9.12ac-octamethyl-(8atH.12btH.14bcH)-Δ¹⁴-eicosahydro-picen；Oleanen-(12)-diyl-(3β.16β)-diformiat；3β.16β-Diformyloxy-oleanen-(12)
• CAS: 64181-08-4
• 化学式: C₃₂H₅₀O₄
• 分子量: 498.747
• InChiKey: KMRQGNIPPLZTFF-HRYXYBQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  36.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  甲酸 、 (3b,16b)-齐墩果-12-烯-3,16-二醇 在 苯 作用下， 生成 3β,16β-bis-formyloxy-olean-12-ene
  参考文献：
  名称：

  148.三萜族。第七部分 马尼拉Elemi树脂的次要三萜成分

  摘要：

  DOI：

  10.1039/jr9400000795

文献信息

• Food Sources of Phytoestrogens and Breast Cancer Risk in Mexican Women
  作者：Luisa Torres-Sànchez、Lizbeth López--Carrillo、Malaquías Ló--Cervantes、Celina Rueda-Neria、Mary S. Wolff

  DOI：10.1207/s15327914nc372_3

  日期：2000.7

  We analyzed the intake of selected foods that contain phytoestrogens in relation to breast cancer (BC) risk using data from a hospital-based case-control study performed in Mexico City from 1994 to 1995. A total of 198 women with BC, aged 21-79 years, were individually age matched to an identical number of women with no breast disease. By a direct interview, information on socioeconomic characteristics and diet was obtained. A semiquantitative questionnaire was used to estimate the frequency of consumption of 95 foods. The effect of selected foods that contain phytoestrogens on BC risk was estimated using logistic regression models. The adjusted odds ratio for the consumption of more than one slice of onion per day and BC was 0.27 (95% confidence interval = 0.16-0.47), with a statistically significant trend (p < 0.001). This protective effect remained after adjustment for known risk factors of BC. Among premenopausal women, there was also a protective and significant effect due to the intake of lettuce and spinach and nonsignificant protective effects for the consumption of apples and herbal tea. Additional studies aimed at evaluating the potential protective effect of particular phytoestrogens bn BC risk are needed.