螺[1,3-二氧戊环-2,6'-双环[2.2.1]庚烷] | 172-67-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 螺[1,3-二氧戊环-2,6'-双环[2.2.1]庚烷]
• 英文名称: Norcampher-ethylenketal
• 英文别名: Spiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane]；spiro[1,3-dioxolane-2,2'-bicyclo[2.2.1]heptane]
• CAS: 172-67-8
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: LHHZJFGOSJEWMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2932999099

反应信息

• 作为反应物：
  描述：

  螺[1,3-二氧戊环-2,6'-双环[2.2.1]庚烷] 、 三氟甲磺酸三甲基硅酯 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以91%的产率得到2-<2-<(trimethylsilyl)oxy>ethoxy>bicyclo<2.2.1>hept-2-ene
  参考文献：
  名称：

  Synthesis of cyclic and acyclic enol ethers (vinyl ethers)

  摘要：

  A general method has been developed for the conversion of both cyclic and acyclic acetals of cyclic ketones, acyclic ketones, and aldehydes into enol ethers through treatment of the acetal with trimethylsilyl triflate in the presence of N,N-diisopropylethylamine. The range of isolated yields of enol ethers from the various classes of acetals was as follows: cyclic acetals of cyclic ketones, 83-98%; acyclic acetals of ketones, 72-94%; acyclic and cyclic acetals of aldehydes, 65-90%.

  DOI：

  10.1021/jo00058a027
• 作为产物：
  描述：

  降樟脑 、 乙二醇 在 magnesium sulfate 、 (E)-1-(甲基磺酰基)-2-苯偶氮 、 原甲酸三甲酯 作用下， 以> 99 %的产率得到螺[1,3-二氧戊环-2,6'-双环[2.2.1]庚烷]
  参考文献：
  名称：

  用于羰基可见光驱动保护的通用无金属协议

  摘要：

  羰基保护：这项工作强调了芳基偶氮砜作为非离子光致产酸剂 (PAG) 在可见光照射下促进醛和酮有效转化为缩醛、缩酮和 1,3-恶唑烷的潜力。这种方法利用了所采用的温和条件，并表现出易于扩展和广泛的底物范围（包括 80 个示例）。

  DOI：

  10.1002/cssc.202201998

文献信息

• SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20210371376A1

  公开（公告）日：2021-12-02

  A salt represented by formula (I): wherein R 1 and R 2 each independently represent a hydroxy group, —O—R 10 , —O—CO—O—R 10 or —O-L 1 -CO—O—R 10 ; L 1 represents an alkanediyl group having 1 to 6 carbon atoms; R 4 , R 5 , R 7 and R 8 each independently represent a halogen atom, an alkyl fluoride group having 1 to 12 carbon atoms or a hydrocarbon group having 1 to 18 carbon atoms, the hydrocarbon group may have a substituent, and —CH 2 — included in the hydrocarbon group may be replaced by —O—, —CO—, —S— or —SO 2 —; R 10 represents an acid-labile group; X 1 and X 2 each independently represent an oxygen atom or a sulfur atom; m1 represents an integer of 1 to 5, m2 and m8 represent an integer of 0 to 5, m4, m5 and m7 represent an integer of 0 to 4; and AI − represents an organic anion.

  一种由化学式（I）表示的盐：其中R1和R2分别代表一个羟基，-O-R10，-O-CO-O-R10或-O-L1-CO-O-R10；L1代表具有1至6个碳原子的烷二基基团；R4、R5、R7和R8分别独立地表示卤素原子，具有1至12个碳原子的烷基氟基团或具有1至18个碳原子的碳氢基团，碳氢基团可能有取代基，并且碳氢基团中包含的-CH2-可被-O-，-CO-，-S-或-SO2-取代；R10代表一个酸敏感基团；X1和X2分别独立地表示一个氧原子或一个硫原子；m1表示1至5的整数，m2和m8表示0至5的整数，m4、m5和m7表示0至4的整数；AI-代表一个有机阴离子。
• SALT, QUENCHER, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20200363720A1

  公开（公告）日：2020-11-19

  Disclosed are a salt represented by formula (I) and a resist composition including the same:

  公开了一种由化学式（I）表示的盐和包括该盐的抗蚀组合物：
• Photochemical reaction of benzene-1,2,4,5-tetracarbonitrile with the ketals of cyclic and bicyclic ketones
  作者：Mariella Mella、Mauro Freccero、Angelo Albini

  DOI：10.1021/jo00084a021

  日期：1994.3

  The radical cations of the ethylene ketals of some cyclic and bicyclic ketones are generated by single electron transfer to excited benzene-1,2,4,5-tetracarbonitrile (TCB). Their fragmentation yields 1,5- and 1,6-distonic radical cations, which add to TCB-. to give [omega-[(2-hydroxyethoxy)carbonyl] alkyl]benzenetricarbonitriles. The reduction of the radical center occurs only to a small extent, and is enhanced in the presence of dodecylmercaptan, in the case of hindered radicals. The reaction of the camphor ethylene ketal (both alkylation of TCB and reduction) occurs with total diastereoselectivity at the reacting radical center.
• Geminal Acylation with Methyl-Substituted Analogues of 1,2-Bis[(trimethylsilyl)oxy]cyclobutene
  作者：Sheldon N. Crane、Tracy J. Jenkins、D. Jean Burnell

  DOI：10.1021/jo971055v

  日期：1997.12.1

  BF3 . Et2O-catalyzed geminal acylation of ketones and acetals with 3-methyl-1,2-bis[(trimethylsilyl)oxy)]cyclobutene (3) provided methylcyclopentanediones in yields that ranged from 40 to 94%. The best substrates were unhindered cyclohexanones. With acetals, stereochemical preferences in the initial Mukaiyama-like aldol step giving cyclobutanones translated into the stereochemistry of the ultimate cyclopentanedione products. With ketones, equilibration of the initial cyclobutanone compounds resulted in cyclopentanedione products with a different stereochemical preference. The gem-dimethylcyclobutene reagent 4 reacted with ketones to give gem-dimethylcyclopentanediones in modest yield. The process was much more stereochemically efficient than the reaction with 3. Rearrangement from the initial cyclobutanone compound was partially diverted toward air-sensitive 3-furanone compounds and ring-opened 1,2-diones. Only furanones (e.g., 52 and 53) were isolated from reactions with the tetramethylcyclobutene 51.
• Burnell, D. Jean; Wu, Yong-Jin, Canadian Journal of Chemistry, 1990, vol. 68, # 6, p. 804 - 811
  作者：Burnell, D. Jean、Wu, Yong-Jin

  DOI：——

  日期：——