1-(ethylthio)heptane-2-ol | 1159011-17-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(ethylthio)heptane-2-ol
• 英文别名: 1-ethylsulfanylheptan-2-ol
• CAS: 1159011-17-2
• 化学式: C₉H₂₀OS
• 分子量: 176.323
• InChiKey: PGLALUPFPMOHPU-UHFFFAOYSA-N

物化性质

• 沸点：
  267.0±13.0 °C(predicted)
• 密度：
  0.933±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  聚合甲醛 、 1-(ethylthio)heptane-2-ol 、 二正丁胺 在 sodium hydroxide 作用下， 以 苯 为溶剂， 以76.6%的产率得到1-(ethylthio)-2-(N,N-dibutylaminomethoxy)heptane
  参考文献：
  名称：

  Synthesis and antimicrobial activity of aminomethoxy-substituted 1-(ethylthio)heptanes

  摘要：

  The Mannich condensation of 1-(ethylthio)heptane-2-ol, formaldehyde and secondary amines taken in equimolar amounts gives rise to new aminomethoxy-substituted 1-(ethylthio)heptanes in a yield of 70-77%. The structure of the synthesized compounds was proved by the elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The compounds were tested as antimicrobial additives to lubricating oils. They were found to suppress effectively the activity of microorganisms.

  DOI：

  10.1134/s1070363213030134
• 作为产物：
  描述：

  1-溴庚烷-2-醇 、 乙硫醇 在 sodium hydroxide 作用下， 以 水 为溶剂， 以68%的产率得到1-(ethylthio)heptane-2-ol
  参考文献：
  名称：

  Synthesis and antimicrobial activity of aminomethoxy-substituted 1-(ethylthio)heptanes

  摘要：

  The Mannich condensation of 1-(ethylthio)heptane-2-ol, formaldehyde and secondary amines taken in equimolar amounts gives rise to new aminomethoxy-substituted 1-(ethylthio)heptanes in a yield of 70-77%. The structure of the synthesized compounds was proved by the elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The compounds were tested as antimicrobial additives to lubricating oils. They were found to suppress effectively the activity of microorganisms.

  DOI：

  10.1134/s1070363213030134

文献信息

• Synthesis and antimicrobial activity of aminomethoxy-substituted 1-(ethylthio)heptanes
  作者：E. G. Mammadbeyli、I. A. Jafarov、S. I. Ibrahimli、T. G. Kyazimova、S. T. Alieva、G. F. Mamedova

  DOI：10.1134/s1070363213030134

  日期：2013.3

  The Mannich condensation of 1-(ethylthio)heptane-2-ol, formaldehyde and secondary amines taken in equimolar amounts gives rise to new aminomethoxy-substituted 1-(ethylthio)heptanes in a yield of 70-77%. The structure of the synthesized compounds was proved by the elemental analysis, IR and H-1 NMR spectroscopy, and mass spectrometry. The compounds were tested as antimicrobial additives to lubricating oils. They were found to suppress effectively the activity of microorganisms.