4,5-Bis(5-chloro-2-methylthiophen-3-yl)-2-(4-chlorophenyl)-1H-imidazole | 1152809-44-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4,5-Bis(5-chloro-2-methylthiophen-3-yl)-2-(4-chlorophenyl)-1H-imidazole
• 英文别名: 4,5-bis(5-chloro-2-methylthiophen-3-yl)-2-(4-chlorophenyl)-1H-imidazole
• CAS: 1152809-44-3
• 化学式: C₁₉H₁₃Cl₃N₂S₂
• 分子量: 439.817
• InChiKey: UZZLZCULKILULE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  85.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4,5-Bis(5-chloro-2-methylthiophen-3-yl)-2-(4-chlorophenyl)-1H-imidazole 在 air 作用下， 以 四氢呋喃 为溶剂， 反应 0.83h， 以57%的产率得到4-(4-Chlorophenyl)-11,12-dimethyl-10,13-dithia-3,5-diazatetracyclo[10.3.0.02,6.07,11]pentadeca-1(15),2(6),3,7-tetraene-9,14-dione
  参考文献：
  名称：

  Synthesis and photophysical properties of thiolactone derivatives

  摘要：

  A class of bis-thiolactone derivatives is prepared by photo-conversion of photochromic diarylethenes with a bis (5-chloro-2-methylthiophen-3-yl) system in moderate yields (50-60%). Bis-thiolactone derivatives show fluorescence in solution with moderate fluorescent quantum yields (0.11-0.17). Reaction mechanism exhibits that the photo-conversion of diarylethenes to bis-thiolactone derivatives undergoes a two-step reaction: photocyclization and photo-oxidation. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.12.057
• 作为产物：
  描述：

  2-氯-5-甲基噻吩 在 吡啶 、 ammonium acetate 、 溶剂黄146 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 4,5-Bis(5-chloro-2-methylthiophen-3-yl)-2-(4-chlorophenyl)-1H-imidazole
  参考文献：
  名称：

  Synthesis and photophysical properties of thiolactone derivatives

  摘要：

  A class of bis-thiolactone derivatives is prepared by photo-conversion of photochromic diarylethenes with a bis (5-chloro-2-methylthiophen-3-yl) system in moderate yields (50-60%). Bis-thiolactone derivatives show fluorescence in solution with moderate fluorescent quantum yields (0.11-0.17). Reaction mechanism exhibits that the photo-conversion of diarylethenes to bis-thiolactone derivatives undergoes a two-step reaction: photocyclization and photo-oxidation. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.12.057

文献信息

• Synthesis and photophysical properties of thiolactone derivatives
  作者：Huan-Huan Liu、Yi Chen

  DOI：10.1016/j.tet.2012.12.057

  日期：2013.2

  A class of bis-thiolactone derivatives is prepared by photo-conversion of photochromic diarylethenes with a bis (5-chloro-2-methylthiophen-3-yl) system in moderate yields (50-60%). Bis-thiolactone derivatives show fluorescence in solution with moderate fluorescent quantum yields (0.11-0.17). Reaction mechanism exhibits that the photo-conversion of diarylethenes to bis-thiolactone derivatives undergoes a two-step reaction: photocyclization and photo-oxidation. (C) 2013 Elsevier Ltd. All rights reserved.