3,3-dimethyl-hex-4t-en-2-one | 74157-92-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,3-dimethyl-hex-4t-en-2-one
• 英文别名: (E)-3,3-dimethylhex-4-en-2-one
• CAS: 74157-92-9
• 化学式: C₈H₁₄O
• 分子量: 126.199
• InChiKey: LCHQSJKSMNPVBS-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,3-dimethyl-hex-4t-en-2-one 以 丙酮 为溶剂， 生成 (Z)-3,3-dimethylhex-4-en-2-one
  参考文献：
  名称：

  Weerdt, Anton J. A. van der; Cerfontain, Hans, Journal of the Chemical Society. Perkin transactions II, 1980, p. 592 - 597

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-4-hexen-2-one 、 碘甲烷 在 potassium tert-butylate 作用下， 生成 反式-3-甲基-3-己烯-2-酮 、 3,3-dimethyl-hex-4t-en-2-one
  参考文献：
  名称：

  Weerdt, Anton J. A. van der; Cerfontain, Hans, Journal of the Chemical Society. Perkin transactions II, 1980, p. 592 - 597

  摘要：

  DOI：

文献信息

• MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
  申请人：Gilead Sciences, Inc.

  公开号：US20170190737A1

  公开（公告）日：2017-07-06

  Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.

  提供的是公式I的化合物： 及其药用可接受的盐和酯。这些化合物、组合物和方法对于治疗病毒感染特别是有用的，尤其是丙型肝炎感染。
• BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES
  申请人：WENDER PAUL A.

  公开号：US20090270492A1

  公开（公告）日：2009-10-29

  Biologically active compounds related to the bryostatin family of compounds, including methods of utilizing the same.

  与拟静脉注射家族相关的生物活性化合物，包括利用这些化合物的方法。
• Byrostatin analogues, synthetic methods and uses
  申请人：Wender A. Paul

  公开号：US20070270485A1

  公开（公告）日：2007-11-22

  Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same.
• COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION
  申请人：Ishida Kenya

  公开号：US20110117147A1

  公开（公告）日：2011-05-19

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from 1-menthol, 1-isopulegol, 3-(1-menthoxy)propan-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.
• Bryostatin Analogues, Synthetic Methods and Uses
  申请人：The Board of Trustees of the Leland Stanford Juni

  公开号：US20130123518A1

  公开（公告）日：2013-05-16

  Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same.