2-methyl-1,6-hexanedialdehyde | 25355-33-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-methyl-1,6-hexanedialdehyde
• 英文别名: 2-Methyl-hexan-dial-(1,6)；2-methyl-hexane-1,6-dial；2-methylhexanedial；2-methyladipaldehyde；α-methyladipaldehyde；2-methyladipoaldehyde
• CAS: 25355-33-3
• 化学式: C₇H₁₂O₂
• 分子量: 128.171
• InChiKey: NICDGFIIDLQPAF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  环戊醇 、 2-methyl-1,6-hexanedialdehyde 在 lithium perchlorate 、 三氟乙酸 作用下， 反应 0.08h， 以75%的产率得到rac-(1S,2S)-2-(cyclopentyloxymethyl)-2-methylcyclopentanol
  参考文献：
  名称：

  Asymmetric Acid-Catalyzed Meerwein−Ponndorf−Verley−Aldol Reactions of Enolizable Aldehydes

  摘要：

  A highly, stereo- and regioselective Meerwein - Ponndorf - Verley - Aldol etherification process of enolizable aldehydes is described. This new transformation is catalyzed by trifluoroacetic acid. The method also allows cross-aldol reactions with alpha-branched enolizable aldehydes and thus provides access to defined configured quaternary stereogenic centers.

  DOI：

  10.1021/ol100093u
• 作为产物：
  描述：

  3-甲基-1-环己烯 在 sodium periodate 、 间氯过氧苯甲酸 、 potassium hydroxide 作用下， 生成 2-methyl-1,6-hexanedialdehyde
  参考文献：
  名称：

  Acid-catalyzed aldol-Meerwein–Ponndorf–Verley-etherification reactions—access to defined configured quaternary stereogenic centers

  摘要：

  A novel asymmetric aldol-reduction-etherification process of aliphatic enolizable aldehydes is described. The intermediately formed aldol adducts-beta-hydroxyaldehydes-were reduced and transformed into the corresponding 1,3-diol ethers by external secondary alcohols at the same time. Thus, with the help of chiral secondary alcohols an access to optically active 1,3-diol ether is given. Furthermore, asymmetric cross-aldol-Meerwein-Ponndorf reactions of enolizable aldehydes can also be realized under these reaction conditions. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.11.069

文献信息

• [EN] HETEREOCYCLIC AGENT AS CATALYTIC STABILIZING AGENT IN A HYDROFORMYLATION PROCESS<br/>[FR] AGENT HÉTÉROCYCLIQUE COMME AGENT DE STABILISATION CATALYTIQUE DANS UN PROCÉDÉ D'HYDROFORMYLATION
  申请人：DOW TECHNOLOGY INVESTMENTS LLC

  公开号：WO2014149915A1

  公开（公告）日：2014-09-25

  A heterocyclic nitrogen stabilizing agent is employed to reduce the rate of catalyst deactivation in a hydroformylation process.

  在氢甲酰化过程中，使用杂环氮稳定剂来降低催化剂失活的速率。
• LINEAR CYCLODEXTRIN COPOLYMERS
  申请人：Davis Mark E.

  公开号：US20130184453A1

  公开（公告）日：2013-07-18

  Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.

  本文描述了线性环糊精共聚物和线性氧化环糊精共聚物，其中包含未氧化和/或氧化的环糊精基团集成到聚合物骨架中。本文还描述了制备这种共聚物的方法。本发明的线性环糊精共聚物和线性氧化环糊精共聚物可用作各种治疗剂的传递载体。
• ORGANOSILICON COMPOUND, THIN FILM FORMING COMPOSITION USING SAME, AND ORGANIC THIN FILM
  申请人：NIPPON SODA CO., LTD.

  公开号：US20150148483A1

  公开（公告）日：2015-05-28

  The present invention is intended to provide an organosilicon compound for forming a novel organic thin film having improved physical properties. An organosilicon compound of the present invention is an organosilicon compound represented by formula (I) R—(CH 2 ) n —SiX 3 (I) (wherein R represents an alkoxy group having 1 to carbon atoms or a phenyl group that optionally has a substituent, X represents a hydroxyl group or a hydrolyzable group, and n represents any integer from 17 to 24). An organic thin film can be formed by mixing the aforementioned organosilicon compound, a compound that can interact with the organosilicon compound, and water in an organic solvent to prepare an organic thin film forming solution, and bringing the organic thin film forming solution into contact with a substrate.

  本发明旨在提供一种有改善物理特性的新型有机薄膜的有机硅化合物。本发明的有机硅化合物是由式（I）R—（CH2）n—SiX3（式中，R表示具有1至碳原子的烷氧基或具有取代基的苯基，X表示羟基或可水解基，n表示从17到24的任意整数）表示的有机硅化合物。可以通过将上述有机硅化合物、能与有机硅化合物相互作用的化合物和水混合在有机溶剂中制备有机薄膜形成溶液，并将有机薄膜形成溶液与基板接触来形成有机薄膜。
• Coating composition and process for manufacturing the same
  申请人：JAPAN SYNTHETIC RUBBER CO., LTD.

  公开号：EP0555879A1

  公开（公告）日：1993-08-18

  A coating composition prepared by adding 0 to 150 parts by weight, in terms of diorganosilane, of a hydrolyzate and/or a partial condensate of an diorganosilane (b), 2 to 300 parts by weight of a vinyl resin containing a silyl group (c), 0.01 to 50 parts by weight of a metal chelate compound (d), and an organic solvent (e), to 100 parts by weight in terms of organosilane of a hydrolyzate and/or a partial condensate of an organosilane (a), to which are added two or more mols of a type of β-diketone and/or β-ketoester (f) for one mol of the metal chelate compound (d).

  一种涂料组合物，其制备方法是将 0 至 150 份（按重量计）二氢硅烷的水解物和/或二氢硅烷的部分缩合物 (b)、2 至 300 份（按重量计）含有硅基的乙烯基树脂 (c)、0.01 至 50 重量份的金属螯合物 (d) 和有机溶剂 (e)、100 重量份的有机硅烷的水解物和/或有机硅烷 (a) 的部分缩合物，其中每 1 摩尔金属螯合物 (d) 加入 2 或更多摩尔的 β-二酮和/或 β-酮酯 (f)。
• Hydroformylation process for producing 1,6-hexanedials
  申请人：UNION CARBIDE COATINGS SERVICE TECHNOLOGY CORP.

  公开号：EP0577042A1

  公开（公告）日：1994-01-05

  This invention relates to a hydroformylation process for producing a 1,6- hexanedial which comprises reacting a butadiene with hydrogen and carbon monoxide in the presence of a catalytic amount of rhodium complexed with certain poly-phosphite ligands to achieve high conversions of the butadiene to the 1,6-hexanedial.

  本发明涉及一种生产 1,6-己二醛的加氢甲酰化工艺，该工艺包括在催化量的与某些多亚磷酸配体络合的铑存在下，使丁二烯与氢气和一氧化碳反应，以实现丁二烯到 1,6-己二醛的高转化率。