(E)-2-[2-(4-methoxyphenyl)vinyl]-6,7-difluoro-8-hydroxyquinoline | 1432043-27-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (E)-2-[2-(4-methoxyphenyl)vinyl]-6,7-difluoro-8-hydroxyquinoline
• 英文别名: 2-(4-methoxystyryl)-6,7-difluoro-8-hydroxyquinoline；6,7-difluoro-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinolin-8-ol
• CAS: 1432043-27-0
• 化学式: C₁₈H₁₃F₂NO₂
• 分子量: 313.304
• InChiKey: PVMCMUYTOLOJOD-QHHAFSJGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  42.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (E)-2-[2-(4-methoxyphenyl)vinyl]-6,7-difluoro-8-hydroxyquinoline 、 zinc diacetate 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Synthesis, structure, and photoluminescence properties of Zn(II) complexes with 2-styryl derivatives of 8-hydroxyquinoline

  摘要：

  Novel Zn(II) complexes with 2-styryl-8-hydroxyquinoline were synthesized and characterized by H-1, F-19, and C-13 NMR spectroscopy and X-ray diffraction analysis. Photoluminescence properties of the ligands and complexes in solutions were studied. The effect of substituents in the quinoline and phenylethenyl fragments on spectral characteristics was discussed.

  DOI：

  10.1134/s1070363214090229
• 作为产物：
  描述：

  6-氨基-2,3-二氟苯酚 在 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 40.0h， 生成 (E)-2-[2-(4-methoxyphenyl)vinyl]-6,7-difluoro-8-hydroxyquinoline
  参考文献：
  名称：

  Synthesis and fluorescent properties of 2-styryl-6,7-difluoro-8-hydroxyquinoline and its Zn(II) complex

  摘要：

  A synthetic approach to 2-methyl-6,7-difluoro-8-hydroxyquinoline, a key intermediate, has been developed. 6,7-Difluoro derivative of 2-styryl substituted 8-hydroxyquinoline and its Zn(II) complex have been obtained. Effects of fluorine atoms in the benzene ring on photophysical properties of 2-styryl-8-hydroxyquinolines and their Zn(II) complexes have been studied. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2013.03.005