3-(4-hydroxymethyl-2-thioxo-thiazol-3-yl)-propionic acid | 16946-36-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-(4-hydroxymethyl-2-thioxo-thiazol-3-yl)-propionic acid
• 英文别名: 3-(2-Carboxy-aethyl)-4-hydroxymethyl-2-thioxo-Δ⁴-thiazolin；3-[4-(Hydroxymethyl)-2-sulfanylidene-1,3-thiazol-3-yl]propanoic acid
• CAS: 16946-36-4
• 化学式: C₇H₉NO₃S₂
• 分子量: 219.285
• InChiKey: VSRSZPHFDAWIKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  118
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  二硫化碳 、 1-氯-3-羟基丙酮 、 β-丙氨酸 生成 3-(4-hydroxymethyl-2-thioxo-thiazol-3-yl)-propionic acid
  参考文献：
  名称：

  Lamon,R.W.; Humphlett,W.J., Journal of Heterocyclic Chemistry, 1967, vol. 4, p. 605 - 609

  摘要：

  DOI：

文献信息

• Sensitizing dye and silver halide photographic material
  申请人：——

  公开号：US20020106593A1

  公开（公告）日：2002-08-08

  Spectral sensitizing dyes represented by the following formulas ( 1 ) to ( 4 ) are disclosed; silver halide photographic materials and thermally developable photosensitive materials containing the dyes are also disclosed. 1

  以下公式（1）至（4）所代表的光谱敏化染料被揭示；同时也揭示了含有这些染料的银盐感光材料和热敏感材料。
• Photothermographic imaging materials and sensitisers therefor
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0616014A2

  公开（公告）日：1994-09-21

  A heptamethine cyanine dye in which both nitrogen atoms of the cyanine chromophore bear a carboxyalkyl substituent comprising an alkyl chain of at least five carbon atoms. The dyes are useful as sensitisers in photothermographic imaging materials.

  一种七甲基氰基染料，其中氰基发色团的两个氮原子都带有一个由至少五个碳原子的烷基链组成的羧烷基取代基。这种染料可用作光热成像材料中的敏化剂。
• Schiff base quinone complexes and optical recording materials comprising the same
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP0802178A2

  公开（公告）日：1997-10-22

  Novel Schiff base quinone complexes are provided. They are useful as anti-fading agents and filter dyes. The anti-fading agents are applicable to heat developable photosensitive materials, silver halide photosensitive materials, and optical recording materials.

  提供了新型希夫碱醌复合物。它们可用作抗褪色剂和过滤染料。抗褪色剂适用于热显影感光材料、卤化银感光材料和光学记录材料。
• Heat development image forming process and heptamethine cyanine compound
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0854382A1

  公开（公告）日：1998-07-22

  A heat development image forming process comprises steps of: imagewise exposing to light a heat developable light-sensitive material comprising a support, a light-sensitive layer and a non-light-sensitive layer, and then heating the light-sensitive material. The light-sensitive layer or the non-light-sensitive layer contains a heptamethine cyanine dye represented by the formula (I): in which Z1 is -CR11R12-, -O-, -S- or -NR13-; Z2 is -CR21R22-, -O-, -S- or -NR23-; each of R1 and R2 independently is an alkyl group, a substituted alkyl group, an alkenyl group, a substituted alkenyl group, an aralkyl group or a substituted aralkyl group; R3 is hydrogen, a halogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an aryl group, a substituted aryl group, a heterocyclic group, a substituted heterocyclic group, cyano, -SO2R31, -OR32, -SR33 or -NR34R35; X is an anion; and n is 0 or 1.

  一种热显影图像形成工艺包括以下步骤：将可热显影的光敏材料（包括支撑物、光敏层和非光敏层）进行图像曝光，然后加热光敏材料。感光层或非感光层含有由式（I）表示的七甲基青染料： 其中 Z1 是-CR11R12-、-O-、-S-或-NR13-； Z2 是-CR21R22-、-O-、-S-或-NR23-； R1 和 R2 各自独立地是烷基、取代的烷基、烯基、取代的烯基、烷基或取代的烷基；R3 是氢、卤素原子、烷基、取代的烷基、环烷基、取代的环烷基、芳基、取代的芳基、杂环基、取代的杂环基、氰基、-SO2R31、-OR32、-SR33 或-NR34R35；X 是阴离子；n 是 0 或 1。
• Heat development image forming process, thermally decoloring image recording process and process for decoloring cyanine dye
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP0911693A1

  公开（公告）日：1999-04-28

  A heat developable light-sensitive material comprises a support, a light-sensitive layer and a non-light-sensitive layer. The light-sensitive layer contains silver halide and a reducing agent. The non-light-sensitive layer contains a cyanine dye represented by the formula (I) or a salt thereof and a base precursor: in which R1 is hydrogen, an aliphatic group, an aromatic group, -NR21R24, -OR21 or -SR21, each of R21 and R24 independently is hydrogen, an aliphatic group or an aromatic group, or R21 and R24 are combined to form a nitrogen-containing heterocyclic ring; R2 is hydrogen, an aliphatic group or an aromatic group; R3 is an aliphatic group; L1 is a methine chain consisting of an odd number of methines; and each of Z1 and Z2 independently is an atomic group forming a five-membered or six-membered nitrogen-containing heterocyclic ring. A heat development image forming process, a thermal image recording material, a thermally decoloring image recording process and a process for decoloring a cyanine dye are also disclosed.

  一种可热显影的光敏材料包括一个支架、一个光敏层和一个非光敏层。感光层含有卤化银和还原剂。非感光层含有由式（I）或其盐代表的氰基染料和碱前体： 其中 R1 是氢、脂肪族基团、芳香族基团、-NR21R24、-OR21 或 -SR21，R21 和 R24 各自独立地是氢、脂肪族基团或芳香族基团，或 R21 和 R24 结合形成含氮杂环；R2 是氢、脂肪族基团或芳香族基团； R3 是脂肪族基团； L1 是由奇数个甲基组成的甲基链；以及 Z1 和 Z2 各自独立地是形成五元或六元含氮杂环的原子团。本发明还公开了一种热显影图像形成工艺、一种热图像记录材料、一种热脱色图像记录工艺和一种氰基染料脱色工艺。