pentadec-12t-en-1-ol | 69222-15-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: pentadec-12t-en-1-ol
• 英文别名: trans-12-Pentadecen-1-ol；(E)-pentadec-12-en-1-ol
• CAS: 69222-15-7
• 化学式: C₁₅H₃₀O
• 分子量: 226.403
• InChiKey: RVFBJVRGHYFUIC-ONEGZZNKSA-N

物化性质

• 沸点：
  295.8±8.0 °C(Predicted)
• 密度：
  0.847±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  16
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  pentadec-12t-en-1-ol 在 jones reagent 、 三氟化硼乙醚 作用下， 以 水 、 丙酮 为溶剂， 反应 5.0h， 生成 (E)-12-pentadecenoic acid methyl ester
  参考文献：
  名称：

  Enzymatic Desaturation of Fatty Acids:  Δ¹¹ Desaturase Activity on Cyclopropane Acid Probes

  摘要：

  The formation of methylenecyclopropanes by enzymatic desaturation of 11-cyclopropylundecanoic acid (1) and its disubstituted derivatives cis- and trans-3-5 has been investigated using the Delta(11) desaturase of Spodoptera littoralis as model enzyme. Gas chromatography coupled to mass spectrometry analyses of methanolyzed lipidic extracts from tissues incubated with each probe revealed that all the cyclopropyl fatty acids were transformed into the corresponding 11-cyclopropylidene acids, except for compound trans-5 (5b), which was not desaturated at C11. The formation of methylenecyclopropane 9 as the only reaction product from 1 indicates that a potential radical intermediate is too short-lived to allow rearrangement reactions. Information on the Delta(11) desaturase substrate binding domain is provided considering the cyclopropyl probes 3-5 as conformationally restricted analogues of the straight-chain substrates.

  DOI：

  10.1021/jo0267100
• 作为产物：
  描述：

  11-溴-1-十一醇 在 盐酸 、 正丁基锂 、 氨 、 sodium 、 lithium 、 对甲苯磺酸 、 lithium bromide 作用下， 以 四氢呋喃 、 甲醇 、 二甲基亚砜 为溶剂， 反应 33.08h， 生成 pentadec-12t-en-1-ol
  参考文献：
  名称：

  Enzymatic Desaturation of Fatty Acids:  Δ¹¹ Desaturase Activity on Cyclopropane Acid Probes

  摘要：

  The formation of methylenecyclopropanes by enzymatic desaturation of 11-cyclopropylundecanoic acid (1) and its disubstituted derivatives cis- and trans-3-5 has been investigated using the Delta(11) desaturase of Spodoptera littoralis as model enzyme. Gas chromatography coupled to mass spectrometry analyses of methanolyzed lipidic extracts from tissues incubated with each probe revealed that all the cyclopropyl fatty acids were transformed into the corresponding 11-cyclopropylidene acids, except for compound trans-5 (5b), which was not desaturated at C11. The formation of methylenecyclopropane 9 as the only reaction product from 1 indicates that a potential radical intermediate is too short-lived to allow rearrangement reactions. Information on the Delta(11) desaturase substrate binding domain is provided considering the cyclopropyl probes 3-5 as conformationally restricted analogues of the straight-chain substrates.

  DOI：

  10.1021/jo0267100

文献信息

• Vesiculated polymer particles
  申请人：Engelbrecht Francis John

  公开号：US20060111474A1

  公开（公告）日：2006-05-25

  Vesiculated polymer particles and a method of manufacture thereof, are suitable for the beneficial replacement of titanium dioxide pigments and extenders amongst others, and have improved opacity, whiteness, scrub resistance and water resistance due. The manufacturing process exhibits effective control of particle size and particle size distribution.

  囊状聚合物颗粒及其制造方法适用于替代二氧化钛颜料和扩展剂等，并具有更好的不透明度、白度、耐擦洗性和耐水性。该制造工艺可有效控制粒度和粒度分布。
• VESICULATED POLYMER PARTICLES
  申请人：Barloworld Plascon S.A (PTY) LTD

  公开号：EP1558657B1

  公开（公告）日：2010-09-15
• US6001913A
  申请人：——

  公开号：US6001913A

  公开（公告）日：1999-12-14
• US6897255B1
  申请人：——

  公开号：US6897255B1

  公开（公告）日：2005-05-24
• US7572846B2
  申请人：——

  公开号：US7572846B2

  公开（公告）日：2009-08-11