5-(hex-5-en-1-yl)dihydrofuran-2(3H)-one | 26524-71-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 5-(hex-5-en-1-yl)dihydrofuran-2(3H)-one
• 英文别名: 5-(hex-5-enyl)dihydro-2(3H)-furanone；4-Hydroxy-dec-9-ensaeurelacton；α-Hexenylbutyrolacton；5-(Hex-5-EN-1-YL)oxolan-2-one；5-hex-5-enyloxolan-2-one
• CAS: 26524-71-0
• 化学式: C₁₀H₁₆O₂
• 分子量: 168.236
• InChiKey: VFQGEAKBDMXMGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(hex-5-en-1-yl)dihydrofuran-2(3H)-one 在 2,6-二甲基吡啶 、 四氧化锇 、 potassium metaperiodate 作用下， 以 水 、 丙酮 为溶剂， 反应 2.5h， 生成 tetrahydro-5-oxo-2-furanpentanal
  参考文献：
  名称：

  Modification of the side chain of micromolide, an anti-tuberculosis natural product

  摘要：

  This paper describes a series of modi. cations of the side chain of micromolide, an anti-tuberculosis natural product. Most of the synthesized compounds showed significantly decreased activities, which suggests that the long aliphatic side chain of micromolide and its double bond are essential to its activity. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.08.027
• 作为产物：
  描述：

  4-hydroxy-9-decenenitrile 在 Rhodococcus rhodochrous IFO 15564 作用下， 以40%的产率得到5-(hex-5-en-1-yl)dihydrofuran-2(3H)-one
  参考文献：
  名称：

  Conversion of Hydroxy Nitriles to Lactones Using Rhodococcus rhodochrous Whole Cells

  摘要：

  DOI：

  10.1021/jo9616623

文献信息

• Ruthenium pincer-catalyzed synthesis of substituted γ-butyrolactones using hydrogen autotransfer methodology
  作者：Miguel Peña-López、Helfried Neumann、Matthias Beller

  DOI：10.1039/c5cc01708d

  日期：——

  The ruthenium pincer-catalyzed synthesis of γ-butyrolactones from 1,2-diols and malonates using borrowing-hydrogen methodology is reported.

  本文报道了使用借氢方法，通过钌夹钳催化从1,2-二醇和丙二酸酯合成γ-丁内酯的过程。

• Polyhydroxyalkanoic Acid Having Vinyl, Ester, Carboxyl or Sulfonic Acid Group and Producing Method Therefor
  申请人：Kenmoku Takashi

  公开号：US20080064828A1

  公开（公告）日：2008-03-13

  The invention is to provide a novel polyhydroxyalkanoate having a reactive function group within the molecule and a producing method therefor In a polyhydroxyalkanoate containing a unit having a vinyl group in a side chain, such vinyl group is utilized for deriving a polyhydroxyalkanoate comprising a carboxyl group or a unit having an amide group and a sulfonic acid group.

  本发明旨在提供一种新型聚羟基烷酸酯，其分子内具有反应性功能团，并提供其制备方法。在含有侧链中具有乙烯基团的聚羟基烷酸酯中，利用该乙烯基团来获得含有羧基或含有酰胺基和磺酸基的聚羟基烷酸酯。
• POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP1758948B1

  公开（公告）日：2009-05-13
• US7557176B2
  申请人：——

  公开号：US7557176B2

  公开（公告）日：2009-07-07
• [EN] POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR<br/>[FR] ACIDE POLYHYDROXYALCANOÏQUE COMPORTANT UN GROUPE VINYLE, ESTER, CARBOXYLE OU ACIDE SULFONIQUE ET PROCÉDÉ DE PRODUCTION DE CET ACIDE
  申请人：CANON KK

  公开号：WO2005121204A2

  公开（公告）日：2005-12-22

  The invention is to provide a novel polyhydroxyalkanoate having a reactive function group within the molecule and a producing method therefor In a polyhydroxyalkanoate containing a unit having a vinyl group in a side chain, such vinyl group is utilized for deriving a polyhydroxyalkanoate comprising a carboxyl group or a unit having an amide group and a sulfonic acid group.