7-Iodooct-7-ene-1,5-diol | 1260168-32-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7-Iodooct-7-ene-1,5-diol
• CAS: 1260168-32-8
• 化学式: C₈H₁₅IO₂
• 分子量: 270.11
• InChiKey: WNFAZANMZMVNTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7-Iodooct-7-ene-1,5-diol 、 乙酸酐 在 吡啶 作用下， 以 乙醚 为溶剂， 以287 mg的产率得到7-iodooct-7-ene-1 5-diyl diacetate
  参考文献：
  名称：

  One-pot sequential deoximation and allylation reactions of aldoximes in aqueous solution

  摘要：

  A simple procedure has been developed for conducting tin-mediated deoximation and allylation reactions of aldoximes in water to form homoallylic alcohols. Employing the new conditions, various homoallylic alcohols were produced in good to excellent yields. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.01.074
• 作为产物：
  描述：

  3-bromo-2-iodoprop-1-ene 、 5-羟基戊醛肟 在 盐酸 、 tin 、 titanium(III) chloride 、 水 作用下， 以 四氢呋喃 为溶剂， 生成 7-Iodooct-7-ene-1,5-diol
  参考文献：
  名称：

  One-pot sequential deoximation and allylation reactions of aldoximes in aqueous solution

  摘要：

  A simple procedure has been developed for conducting tin-mediated deoximation and allylation reactions of aldoximes in water to form homoallylic alcohols. Employing the new conditions, various homoallylic alcohols were produced in good to excellent yields. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.01.074

文献信息

• Tin Mediated Allylation Reactions of Enol Ethers in Water
  作者：Mei-Huey Lin、Shiang-Fu Hung、Long-Zhi Lin、Wen-Shing Tsai、Tsung-Hsun Chuang

  DOI：10.1021/ol102825t

  日期：2011.1.21

  Under tin-mediated Barbier-type reaction conditions, hydration of enol ethers takes place to form aldehydes that undergo allylation reactions. By using this process, various homoallylic alcohols and 2-halohomoallylic alcohols are produced in good to excellent yields.