dihydroxybutene | 759405-15-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: dihydroxybutene
• 英文别名: cis-butenediol；butene diol；butenediol；But-1-ene-1,1-diol
• CAS: 759405-15-7
• 化学式: C₄H₈O₂
• 分子量: 88.1063
• InChiKey: CPRDLBPDNZTCSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  6
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  ethyl(6-iodo-4-methyl-β-carboline)-3-carboxylate 、 碳酸氢钠 、 dihydroxybutene 在 氯化钯 氩 、 乙酸乙酯 、 silica gel 、 甲苯 、 ethyl acetate diisopropyl ether 作用下， 以 N-甲基吡咯烷酮 为溶剂， 以yields 185 mg (26% of theory) of 6-(2-hydroxytetrahydrofuran-4-yl)-4-methyl-β-carboline-3-carboxylic acid ethyl ester, mp 177°-180° C.的产率得到6-(2-hydroxytetrahydrofuran-4-yl)-4-methyl-β-carboline-3-carboxylic acid ethyl ester
  参考文献：
  名称：

  Substituted .beta.-carbolines, and use thereof as medicinal agents

  摘要：

  化合物I的新型取代.beta.-咔唑衍生物，其中R.sup.3是公式##STR2##的氧代二唑基残基，其中R.sup.5代表低于3个碳原子的低级烷基或酯##STR3##，其中R.sup.6是氢或低于3个碳原子的低级烷基，R.sup.4是氢，低于3个碳原子的低级烷基或CH.sub.2 OR.sup.9，其中R.sup.9是低于3个碳原子的低级烷基，R.sup.A是苯基或含有2-10个碳原子的烃基残基，可以是环状或非环状的，饱和或不饱和的，支链或直链的，可以选择地被氧、酮、甲酰、OH、低于3个碳原子的O-烷基或苯基取代，在环状烃基残基中，CH.sub.2-基可以被氧替换，对中枢神经系统产生作用，因此适用于作为精神药物。

  公开号：

  US04623649A1
• 作为产物：
  描述：

  1,4-二溴-2-丁烯 、 (Z)-1,2-dibromo-2-butene 在 sodium formate 作用下， 以 正庚烷 、 水 为溶剂， 生成 dihydroxybutene
  参考文献：
  名称：

  Process for production of alkenediols

  摘要：

  烯丙二醇是在碱金属甲酸的存在下，通过二溴代烯烃的水解而产生的。在一种优选的实施方案中，通过以下一系列步骤制备烯丙二醇，尤其是2-丁烯-1,4-二醇：先用溴化亚铜对共轭双烯进行溴代反应，然后在碱金属甲酸的存在下将得到的二溴丁烯水解为烯丙二醇，最后再生出溴化亚铜和碱金属甲酸，因此只消耗了共轭双烯、氧气和水。

  公开号：

  US04306100A1

文献信息

• RF-glycols containing two perfluoroalkylthio groups and useful
  申请人：Ciba-Geigy Corporation

  公开号：US04001305A1

  公开（公告）日：1977-01-04

  Perfluoroalkylthio glycols and esters thereof can be prepared by the free-radical catalyzed addition of a perfluoroalkylthiol to an acetylenic alcohol or ester thereof. The compounds obtained are useful intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. In one embodiment, a perfluoroalkylthio glycol can be reacted with a diisocyanate to obtain a polyurethane containing perfluoroalkylthio groups, which polyurethanes are useful as coatings to provide oil and water repellence to textiles and as additives to plastics to provide mold-release and other desirable properties.

  全氟烷基硫醇甘油及其酯类化合物可以通过自由基催化的方式将全氟烷基硫醇加成到乙炔醇或其酯类化合物中制备。所得化合物是合成具有低自由表面能的氟化学品的有用中间体，具有防水和防油性能。在一种实施方式中，全氟烷基硫醇甘油可以与二异氰酸酯反应，得到含有全氟烷基硫醇基团的聚氨酯，这些聚氨酯可用作涂料，为纺织品提供防水和防油性能，也可用作塑料添加剂，提供脱模和其他理想性能。
• New R.sub.f -glycols containing two perfluoroalkylthio groups and useful
  申请人：Ciba-Geigy Corporation

  公开号：US03935277A1

  公开（公告）日：1976-01-27

  Perfluoroalkylthio glycols and esters thereof can be prepared by the free-radical catalyzed addition of a perfluoroalkylthiol to an acetylenic alcohol or ester thereof. The compounds obtained are useful intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. In one embodiment, a perfluoroalkylthio glycol can be reacted with a diisocyanate to obtain a polyurethane containing perfluoroalkylthio groups, which polyurethanes are useful as coatings to provide oil and water repellence to textiles and as additives to plastics to provide mold-release and other desirable properties.

  全氟烷基硫醇甘醇和其酯类可以通过自由基催化的方式将全氟烷基硫醇加成到乙炔醇或其酯类中来制备。所得化合物是合成低自由表面能的氟化学品的有用中间体，具有抗油和抗水性能。在一个实施例中，全氟烷基硫醇甘醇可以与二异氰酸酯反应，得到含有全氟烷基硫醇基团的聚氨酯，这些聚氨酯可用作涂料，为纺织品提供抗油和抗水性能，也可用作塑料添加剂，提供脱模和其他理想性能。
• Urethanes containing two perfluoroalkylthio groups
  申请人：Ciba-Geigy Corporation

  公开号：US04054592A1

  公开（公告）日：1977-10-18

  Perfluoroalkylthio glycols and esters thereof can be prepared by the free-radical catalyzed addition of a perfluoroalkylthiol to an acetylenic alcohol or ester thereof. The compounds obtained are useful intermediates for the synthesis of fluorochemicals with low free surface energies having oil and water repellent properties. In one embodiment, a perfluoroalkylthio glycol can be reacted with a diisocyanate to obtain a polyurethane containing perfluoroalkylthio groups, which polyurethanes are useful as coatings to provide oil and water repellence to textiles and as additives to plastics to provide mold-release and other desirable properties.

  全氟烷基硫醇甘油及其酯类化合物可以通过自由基催化的方式将全氟烷基硫醇加成到乙炔醇或其酯类化合物中来制备。所得化合物是合成低自由表面能的氟化学品的有用中间体，具有抗油和抗水性能。在一种实施例中，全氟烷基硫醇甘油可以与二异氰酸酯发生反应，得到含有全氟烷基硫基团的聚氨酯，这些聚氨酯可用作涂层，为纺织品提供抗油和抗水性能，也可用作塑料添加剂，提供脱模和其他理想性能。
• Process for the preparation of glyceraldehyde and derivatives thereof
  申请人：Akzo Nobel NV

  公开号：US06320084B2

  公开（公告）日：2001-11-20

  The invention pertains to a process for the preparation of glyceraldehyde, or an acetal or a hemiacetal thereof, characterized in that 3-butene-1,2-diol is dissolved in a lower alkanol and is subjected to ozonolysis to obtain a 3-hydroperoxy-3-alkoxy-propane-1,2-diol, which is subjected to a reductive treatment to obtain a hemiacetal of glyceraldehyde, which optionally may be converted into glyceraldehyde or an acetal or hemiacetal thereof, and to a process wherein the hemiacetal of glyceraldehyde is converted to a 3-aminopropane-1,2-diol derivative, by subjecting the hemiacetal of glyceraldehyde to a reductive treatment in the presence of ammonia or a primary or secondary amine. Preferably, the hemiacetal of glyceraldehyde is subjected to a reductive treatment in the presence of an amine with the formula R1R2NH, wherein R1 and R2 independently are hydrogen or an alkyl group with 1-18 carbon atoms, or R1 and R2 together with the nitrogen atom to which they are bonded form a 5- or 6-membered ring, to give a compound with the formula R1R2N—CH2—CHOH—CH2OH, wherein R1 and R2 have the previously given meanings.

  本发明涉及一种制备甘油醛或其缩醛或半缩醛的方法，其特征在于将3-丁烯-1,2-二醇溶解在较低的烷基醇中，并经过臭氧化反应以获得3-羟基过氧基-3-烷氧基-丙烷-1,2-二醇，然后进行还原处理以获得甘油醛的半缩醛，该半缩醛可以选择性地转化为甘油醛或其缩醛或半缩醛。本发明还涉及一种方法，其中将甘油醛的半缩醛转化为3-氨基丙烷-1,2-二醇衍生物，通过在氨或一次或二次胺的存在下对甘油醛的半缩醛进行还原处理。优选地，将甘油醛的半缩醛在式为R1R2NH的胺的存在下进行还原处理，其中R1和R2独立地为氢或具有1-18个碳原子的烷基，或R1和R2与它们所连接的氮原子形成5-或6-成员环，以给出式为R1R2N-CH2-CHOH-CH2OH的化合物，其中R1和R2具有先前给定的含义。
• METHOD FOR PRODUCING ALDEHYDE FUNCTIONAL COMPOUNDS
  申请人：Meier Michael A.R.

  公开号：US20120022276A1

  公开（公告）日：2012-01-26

  The invention relates to a method for producing aldehyde functional compounds by a cross-metathesis reaction of an olefinic compound having at least one hydroxy group and at least one C—C double bond with at least one at least monounsaturated fatty acid or at least one at least monounsaturated fatty acid derivative, in the presence of a metathesis catalyst at a maximum temperature of 180° C. and in the presence of at least one reagent that acts as a protective group-forming compound in relation to the aldehyde group of the aldehyde functional compounds.

  本发明涉及一种方法，通过交叉烯烃反应，在存在最高温度为180℃的交换催化剂和至少一种至少单不饱和脂肪酸或至少一种至少单不饱和脂肪酸衍生物的情况下，将至少具有一个羟基和至少一个C-C双键的烯烃化合物与其反应，形成醛官能团化合物，并在至少存在一种作为保护基形成化合物相对于醛基的试剂的情况下进行。