(3E)-pentadec-3-ene-5,7-diyn-2-one | 306997-54-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3E)-pentadec-3-ene-5,7-diyn-2-one
• 英文别名: Montiporyne A；(E)-pentadec-3-en-5,7-diyn-2-one
• CAS: 306997-54-6
• 化学式: C₁₅H₂₀O
• 分子量: 216.323
• InChiKey: DKCBYRCFPIHFRI-BUHFOSPRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (3E)-pentadec-3-ene-5,7-diyn-2-one 生成 montiporyne B
  参考文献：
  名称：

  Synthesis of montiporynes A and B

  摘要：

  Montiporynes A and B, that were among the recently isolated diacetylenic ketones from the stony coral Montipora sp., and reported to possess in vitro cytotoxic activity against several human solid tumor cells, have been synthesized ill three simple steps from readily available materials. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)02143-8
• 作为产物：
  描述：

  1-壬炔 在 四氢吡咯 、 N-碘代丁二酰亚胺 、 copper(l) iodide 、 草酰氯 、 silver nitrate 、 二甲基亚砜 、 三乙胺 作用下， 以 丙酮 为溶剂， 生成 (3E)-pentadec-3-ene-5,7-diyn-2-one
  参考文献：
  名称：

  Synthesis of montiporynes A and B

  摘要：

  Montiporynes A and B, that were among the recently isolated diacetylenic ketones from the stony coral Montipora sp., and reported to possess in vitro cytotoxic activity against several human solid tumor cells, have been synthesized ill three simple steps from readily available materials. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)02143-8

文献信息

• Synthesis of naturally occurring polyacetylenes via a bis-silylated diyne
  作者：Vito Fiandanese、Daniela Bottalico、Giuseppe Marchese、Angela Punzi

  DOI：10.1016/j.tet.2006.03.043

  日期：2006.5

  A straightforward synthesis of a series of naturally occurring polyacetylenes has been developed, including the montiporynes A C ells, the atractylodin, with antibiotic at and C, possessing cytotoxic activity against several human solid tumor c activity against Escherichia coli, and triynes, which display insecticidal activities, starting from the readily available 1,4-bis(trimethylsilyl)-1,3-butadiyne. (c) 2006 Elsevier Ltd. All rights reserved.
• Synthesis of montiporynes A and B
  作者：Traci J Speed、Dasan M Thamattoor

  DOI：10.1016/s0040-4039(01)02143-8

  日期：2002.1

  Montiporynes A and B, that were among the recently isolated diacetylenic ketones from the stony coral Montipora sp., and reported to possess in vitro cytotoxic activity against several human solid tumor cells, have been synthesized ill three simple steps from readily available materials. (C) 2002 Elsevier Science Ltd. All rights reserved.