(3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-yl)methanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-yl)methanol
• 英文别名: ProDOT-OH；(3,4-Dihydro-2h-thieno[3,4-b][1,4]dioxepin-3-yl)methanol；3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-ylmethanol
• 化学式: C₈H₁₀O₃S
• 分子量: 186.232
• InChiKey: KPUHBZKDYLABOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  十一烷酸 、 (3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-yl)methanol 在 4-二甲氨基吡啶 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 生成 (3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-yl)methyl undecanoate
  参考文献：
  名称：

  SUPEROLEOPHOBIC AND/OR SUPERHYDROPHOBIC MATERIAL, PROCESS FOR PREPARING SAME AND APPLICATIONS THEREOF

  摘要：

  该发明涉及一种多层超疏水和/或超疏油材料，包括：一方面，第一组分是导电基底或已经被处理为导电的基底（1）：其表面经过化学和/或物理处理（2）并且包含第一粘附促进导电层（3）；或者包含第一粘附促进导电层（3）；另一方面，至少另一组分是由一个或多个以芳香或杂芳环为基础的单体构成的超疏水和/或超疏油聚合物或共聚物层（4、5或6），这些单体被一个或多个氟碳和/或烃链取代。其特征在于所述材料的各组分在导电基底或先前被处理为导电的基底（1）上沉积的第一层与所述材料的最后一层之间遵守逐渐增加的疏水性梯度。

  公开号：

  US20160096845A1
• 作为产物：
  描述：

  3,4-二甲氧基噻吩 、 2-羟甲基-1,3-丙二醇 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 72.0h， 生成 (3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-3-yl)methanol
  参考文献：
  名称：

  SUPEROLEOPHOBIC AND/OR SUPERHYDROPHOBIC MATERIAL, PROCESS FOR PREPARING SAME AND APPLICATIONS THEREOF

  摘要：

  该发明涉及一种多层超疏水和/或超疏油材料，包括：一方面，第一组分是导电基底或已经被处理为导电的基底（1）：其表面经过化学和/或物理处理（2）并且包含第一粘附促进导电层（3）；或者包含第一粘附促进导电层（3）；另一方面，至少另一组分是由一个或多个以芳香或杂芳环为基础的单体构成的超疏水和/或超疏油聚合物或共聚物层（4、5或6），这些单体被一个或多个氟碳和/或烃链取代。其特征在于所述材料的各组分在导电基底或先前被处理为导电的基底（1）上沉积的第一层与所述材料的最后一层之间遵守逐渐增加的疏水性梯度。

  公开号：

  US20160096845A1

文献信息

• Process for making biosensor
  申请人：NovioSense B.V.

  公开号：EP2653868A1

  公开（公告）日：2013-10-23

  A process for making a biosensor comprising a hollow coil comprising wires coiled in parallel and an electronic circuit component connected to the coil, the process comprising: 1) providing a mandrel on which wires including at least a first wire, a second wire and a third wire are wound in parallel, 2a) immersing the mandrel in a first buffer solution comprising a first bioreceptor, a first monomer and optional additives, 2b) arranging the wires such that the first wire may be used as a working electrode, the second wire may be used as a counter electrode and the third wire may be used as a reference electrode of a three electrode electrochemical cell used in an electropolymerisation process, 3) passing electric current through the first wire to form a first biocompatible coating of a first polymer polymerized from the first monomer comprising the first bioreceptor on the first wire, 4) removing the coil from the mandrel, 5) connecting the wires to their respective points of the electronic circuit component such that the first wire may be used as a working electrode, the second wire may be used as a counter electrode and the third wire may be used as a reference electrode and wherein the electronic circuit component is configured such that it can generate an input signal for a wireless receiver based upon the activity of the bioreceptor and wirelessly send the input signal to the wireless receiver.

  一种制造生物传感器的工艺，该传感器包括一个由平行卷绕的导线组成的空心线圈和一个连接到线圈上的电子电路元件，该工艺包括：1）提供一个心轴，在心轴上平行卷绕至少包括第一根导线、第二根导线和第三根导线在内的导线；2a）将心轴浸入包含第一种生物受体、第一种单体和可选添加剂的第一缓冲溶液中；2b）排列导线，使第一根导线可用作工作电极，第二根导线可用作对电极，第三根导线可用作电聚合过程中使用的三电极电化学电池的参比电极、3) 将电流通过第一导线，以在第一导线上形成由包含第一生物受体的第一单体聚合而成的第一聚合物的第一生物相容性涂层， 4) 将线圈从心轴上取下， 5) 将导线连接到电子电路组件的各自点上，以便将第一导线用作工作电极、第二根导线可用作对电极，第三根导线可用作参比电极，其中，电子电路组件的配置使其能够根据生物受体的活动为无线接收器生成输入信号，并以无线方式将输入信号发送到无线接收器。
• MATERIAU SUPEROLEOPHOBE ET/OU SUPERHYDROPHOBE, SON PROCEDE DE PREPARATION ET SES APPLICATIONS
  申请人：CNRS (Centre National de la Recherche Scientifique)

  公开号：EP2999703B1

  公开（公告）日：2018-10-24
• PROCESS FOR MAKING BIOSENSOR
  申请人：NOVIOSENSE B.V.

  公开号：US20150068028A1

  公开（公告）日：2015-03-12

  A process for making a biosensor comprising a hollow coil having wires coiled in parallel and an electronic circuit component connected to the coil, the process including: 1) providing a mandrel on which wires including at least a first wire, a second wire and a third wire are wound in parallel, 2a) immersing the mandrel in a first buffer solution comprising a first bioreceptor, a first monomer and optional additives, 2b) arranging the wires such that the first wire may be used as a working electrode, the second wire may be used as a counter electrode and the third wire may be used as a reference electrode of a three electrode electrochemical cell used in an electropolymerisation process, 3) passing electric current through the first wire to form a first biocompatible coating of a first polymer polymerized from the first monomer comprising the first bioreceptor on the first wire, 4) removing the coil from the mandrel, 5) connecting the wires to their respective points of the electronic circuit component such that the first wire may be used as a working electrode, the second wire may be used as a counter electrode and the third wire may be used as a reference electrode and wherein the electronic circuit component is configured such that it can generate an input signal for a wireless receiver based upon the activity of the bioreceptor and wirelessly send the input signal to the wireless receiver.
• US9755390B2
  申请人：——

  公开号：US9755390B2

  公开（公告）日：2017-09-05
• US9981982B2
  申请人：——

  公开号：US9981982B2

  公开（公告）日：2018-05-29