[(2R,3S,4S,5R)-6-acetyloxy-2-(acetyloxymethyl)-4,5-dibenzoyloxyoxan-3-yl] benzoate | 363619-55-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [(2R,3S,4S,5R)-6-acetyloxy-2-(acetyloxymethyl)-4,5-dibenzoyloxyoxan-3-yl] benzoate
• CAS: 363619-55-0
• 化学式: C₃₁H₂₈O₁₁
• 分子量: 576.557
• InChiKey: VXBGYMDRYMEEPX-NLWNTQDRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  42
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  141
• 氢给体数：
  0
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  [(2R,3S,4S,5R)-6-acetyloxy-2-(acetyloxymethyl)-4,5-dibenzoyloxyoxan-3-yl] benzoate 在 三氟甲磺酸三甲基硅酯 、 potassium carbonate 、 乙酰氯 、 苄胺 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 为溶剂， 反应 123.0h， 生成 4-methoxyphenyl 2-O-acetyl-3,4-di-O-benzoyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside
  参考文献：
  名称：

  Domain decomposition methods of dual-primal FETI type for edge element approximations in three dimensions

  摘要：

  We consider domain decomposition algorithms of FETI type for edge element approximations in three dimensions. We first show that a strong coupling exists between tangential degrees of freedom associated to the subdomain edges and faces. We then propose a dual-primal FETI algorithm that relies on a change of basis and on a suitable choice of a coarse space. We give a logarithmic bound for the condition number of the resulting preconditioned operator. Numerical results confirm this bound and the necessity of performing a change of basis. (C) 2004 Academie des sciences. Published by Elsevier SAS. All fights reserved.

  DOI：

  10.1016/j.crma.2004.09.021
• 作为产物：
  描述：

  1,6-di-O-acetyl-2,3,4-tri-O-benzyl-α/β-D-galactopyranose 在 palladium dihydroxide 氢气 作用下， 以 吡啶 、 甲醇 为溶剂， 生成 [(2R,3S,4S,5R)-6-acetyloxy-2-(acetyloxymethyl)-4,5-dibenzoyloxyoxan-3-yl] benzoate
  参考文献：
  名称：

  Synthesis of β-d-Galp-(1→4)-α-d-Manp methanephosphonate, a substrate analogue for the elongating α-d-mannosyl phosphate transferase in the Leishmania

  摘要：

  An isosteric C-glycoside phosphono analogue of dec-9-enyl beta -D-galactopyranosyl-(1 -->4)-alpha -D-mannopyranosyl phosphate was synthesised and showed high biological activity in the Leishmania MPT assay. A one-step Horner-Emmons/Michael reaction was developed for the stereoselective preparation of cc-D-mannosyl methanephosphonate derivatives. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)00961-3

文献信息

• An Efficient Method for the Synthesis of 2,6-Branched Galacto-Oligo­saccharides and Its Applications to the Synthesis of Three Tetrasaccharides and a Hexasaccharide Related to the Arabinogalactans (AGs)
  作者：Jun Ning、Yuetao Yi、Zhe Yao

  DOI：10.1055/s-2003-42109

  日期：——

  An efficient method for the synthesis of 2,6-branched galacto-oligosaccharides has been developed by using 6-O-Ac-2,3,4-tri-O-Bz-α-d-galactopyranosyl trichloroacetimidate, 2,6-di-O-Ac-3,4-di-O-Bz-α-d-galactopyranosyl trichloroacetimidate and 2-O-Ac-3,4,6-tri-O-Bz-α-d-galactopyranosyl trichloroacetimidate as synthons. Three tetrasaccharides and a hexasaccharides related to AGs from plants were readily prepared using this method.

  通过使用6-O-Ac-2,3,4-三-O-Bz-α-d-半乳糖吡喃糖苷三氯乙酰亚胺、2,6-二-O-Ac-3,4-二-O-Bz-α-d-半乳糖吡喃糖苷三氯乙酰亚胺和2-O-Ac-3,4,6-三-O-Bz-α-d-半乳糖吡喃糖苷三氯乙酰亚胺作为合成砌块，开发了一种高效合成2,6-支化半乳寡糖的方法。利用这种方法，可以方便地制备与植物来源的AGs相关的三种四糖和一种六糖。