1,3-dihydro-3-oxo-4-isobenzofurancarboxylic acid | 4792-28-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异香豆素
• 英文名称: 1,3-dihydro-3-oxo-4-isobenzofurancarboxylic acid
• 英文别名: 7-Carboxy-phthalid；3-oxo-1H-2-benzofuran-4-carboxylic acid
• CAS: 4792-28-3
• 化学式: C₉H₆O₄
• mdl: MFCD02323395
• 分子量: 178.144
• InChiKey: OBYSXZQKRYKDPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,3-dihydro-3-oxo-4-isobenzofurancarboxylic acid 在 磷化氢 、 氢碘酸 作用下， 生成 3-甲基邻苯二甲酸
  参考文献：
  名称：

  Derivatives of Hemimellitic Acid. A Synthesis of Erythrocentaurin¹

  摘要：

  DOI：

  10.1021/jo01032a012
• 作为产物：
  描述：

  7-<2-(trimethylsilyl)ethoxycarbonyl>phthalide 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以74%的产率得到1,3-dihydro-3-oxo-4-isobenzofurancarboxylic acid
  参考文献：
  名称：

  Batchelor, Mark J.; Mellor, John M., Journal of the Chemical Society. Perkin transactions I, 1989, p. 985 - 995

  摘要：

  DOI：

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION
  申请人：GIUSTINIANI Pascal

  公开号：US20090028807A1

  公开（公告）日：2009-01-29

  The present application relates to a cosmetic or pharmaceutical, in particular lipstick, composition comprising a polycondensate The application also relates to a method of cosmetic treatment using the composition, the polycondensate thus defined and a method of preparing the polycondensate.

  本申请涉及一种化妆品或药用品，特别是口红，包括聚缩酸酯的组合物。该申请还涉及一种使用该组合物进行化妆处理的方法，所述聚缩酸酯的定义以及一种制备聚缩酸酯的方法。
• COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT
  申请人：Malle Gerard

  公开号：US20100272660A1

  公开（公告）日：2010-10-28

  The present application relates to a cosmetic or pharmaceutical composition comprising a polycondensate capable of being obtained by the reaction of the following monomers alone: of 10 to 30% by weight, relative to the total weight of the polycondensate, of one or more polyols comprising 3 to 6 hydroxyl groups; of 30 to 80% by weight, relative to the total weight of the polycondensate, of one or more linear, branched and/or cyclic, saturated or unsaturated, non-aromatic monocarboxylic acids comprising 6 to 32 carbon atoms; of 1 to 40% by weight, relative to the total weight of the polycondensate, of one or more polycarboxylic acids and/or cyclic anhydrides of such a polycarboxylic acid and/or lactones comprising at least one COOH group; and optionally of 0.1 to 15% by weight, relative to the total weight of the polycondensate, of one or more silicones having a hydroxyl and/or carboxyl functional group. The application also relates to a method of cosmetic treatment using the said composition, and the polycondensate thus defined.

  本申请涉及一种化妆品或药用组合物，包括由以下单体反应而得的聚缩酸酯：相对于聚缩酸酯的总重量，占10至30%的一种或多种含有3至6个羟基的多元醇；占30至80%的一种或多种线性、支链和/或环状、饱和或不饱和、非芳香族的单羧酸，含有6至32个碳原子；占聚缩酸酯总重量的1至40%的一种或多种多羧酸和/或多羧酸的环状酐和/或含有至少一个COOH基团的内酯；以及可选地占聚缩酸酯总重量的0.1至15%的一种或多种硅氧烷，具有羟基和/或羧基官能团。该申请还涉及使用所述组合物进行化妆处理的方法，以及如此定义的聚缩酸酯。
• [EN] DIELS-ALDER REACTION WITH FURANICS TO OBTAIN AROMATICS<br/>[FR] RÉACTION DE DIELS-ALDER AVEC DES COMPOSÉS FURANIQUES POUR OBTENIR DES COMPOSÉS AROMATIQUES
  申请人：TNO

  公开号：WO2020046124A1

  公开（公告）日：2020-03-05

  The present invention is directed to the preparation of phthalic anhydride compounds and the intermediate phthalide compounds. In particular, the invention is directed to an improved bio-based route from furanic compounds to phthalic anhydride compounds by reacting furfuryl alcohol (i.e. 2-hydroxymethylfuran) or an analogue thereof having a nucleophilic atom on the 2-methyl, with a dienophile comprising an α,β-unsaturated carbonyl comprising an α'-leaving group. The inventions further involved preparation of phthalic anhydride compounds, phthalic acid compounds and reduction products of the intermediate phthalide compounds.

  本发明涉及邻苯二甲酸酐化合物和中间苯酞化合物的制备。具体来说，本发明涉及一种改进的基于生物的途径，从呋喃化合物到邻苯二甲酸酐化合物的制备方法，通过将呋喃基醇（即2-羟甲基呋喃）或具有2-甲基上带有亲核原子的类似物与含有α，β-不饱和羰基和α'-脱离基团的双烯组分反应。该发明还涉及邻苯二甲酸酐化合物、邻苯二甲酸化合物以及中间苯酞化合物的还原产物的制备。
• [EN] DIELS- ALDER RING-OPENING PROCESS<br/>[FR] PROCÉDÉ D'OUVERTURE DE CYCLE DE DIELS-ALDER
  申请人：TNO

  公开号：WO2019212338A1

  公开（公告）日：2019-11-07

  The invention is directed to a process for the ring-opening of a cycloadduct of formula I obtainable from a reaction of a furanic compound and a diene, said process comprising contacting the cycloadduct with an acidic mixture comprising sulfuric acid and an activating agent to obtain a ring-opened product. The present invention is particularly directed a continuous process.

  该发明涉及一种用于打开式环化合物的环开放过程，所述环化合物的结构式为I，可从呋喃类化合物和二烯烃的反应中获得，所述过程包括将环化合物与含有硫酸和活化剂的酸性混合物接触，以获得一个环开放产物。本发明特别涉及一种连续过程。