DEUTERATED 1-PIPERAZINO-3-PHENYL-INDANES FOR TREATMENT OF SCHIZOPHRENIA
申请人:JORGENSEN Morten
公开号:US20120322811A1
公开(公告)日:2012-12-20
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D
1
and D
2
as well as the 5HT
2
receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.
DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA
申请人:H. LUNDBECK A/S
公开号:US20130281436A1
公开(公告)日:2013-10-24
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D
1
and D
2
as well as the 5HT
2
receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.
6-chloro-3-(phenyl-d5)-inden-1-one and use thereof
申请人:H. LUNDBECK A/S
公开号:US20150336867A1
公开(公告)日:2015-11-26
The present invention discloses the compound 6-chloro-3-(phenyl-d
5
)-inden-1-one (I) and routes of synthesis to obtain (I). In a further aspect the present invention discloses the use of (I) for the synthesis of (S)-6-chloro-3-(phenyl-d
5
)-indan-1-one.
Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia
申请人:H. Lundbeck A/S
公开号:US20150307458A1
公开(公告)日:2015-10-29
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D
1
and D
2
as well as the 5HT
2
receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.