3,5-bis(4-methylthiophenyl)-4-amino-1,2,4-triazole | 51770-35-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3,5-bis(4-methylthiophenyl)-4-amino-1,2,4-triazole
• 英文别名: 2,5-bis(2-thienyl)-4-amino-1,2,4-triazole；3,5-di-thiophen-2-yl-[1,2,4]triazol-4-ylamine；Di(thienyl-2)-2,5-amino-1-triazole-1,3,4；3,5-di(2-thienyl)-4H-1,2,4-triazol-4-amine；3,5-dithiophen-2-yl-1,2,4-triazol-4-amine
• CAS: 51770-35-5
• 化学式: C₁₀H₈N₄S₂
• 分子量: 248.332
• InChiKey: QPJCHKDJMGRDEE-UHFFFAOYSA-N

物化性质

• 熔点：
  293-294 °C
• 沸点：
  506.0±48.0 °C(Predicted)
• 密度：
  1.61±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  113
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3,5-bis(4-methylthiophenyl)-4-amino-1,2,4-triazole 在 硝酸 、 sodium nitrite 作用下， 以 水 为溶剂， 生成 3,5-di-thiophen-2-yl-1H-[1,2,4]triazole
  参考文献：
  名称：

  Decroix,B. et al., Bulletin de la Societe Chimique de France, 1976, p. 621 - 627

  摘要：

  DOI：
• 作为产物：
  描述：

  2-氰基噻吩 在 盐酸肼 、 一水合肼 作用下， 以 乙二醇 为溶剂， 以72%的产率得到3,5-bis(4-methylthiophenyl)-4-amino-1,2,4-triazole
  参考文献：
  名称：

  新的3,5-二取代-4-氨基-1,2,4-三唑的简单一步合成

  摘要：

  在氮气氛下，在乙烯或二甘醇中，芳族腈与二盐酸肼或硫酸盐与过量的水合肼反应，制得了许多对称的3,5-二取代的4-氨基-1,2,4-三唑。 。通过分析和光谱数据证实了新的三唑衍生物的结构。

  DOI：

  10.1002/jhet.5570360123

文献信息

• A simple one step synthesis of new 3,5-disubstituted-4-amino-1,2,4-triazoles
  作者：Fouad Bentiss、Michel Lagrenée、Michel Traisnel、Bouchaib Mernari、Hassan Elattari

  DOI：10.1002/jhet.5570360123

  日期：1999.1

  by the reaction of aromatic nitriles with hydrazine dihydrochloride or sulfate with an excess of hydrazine hydrate in ethyl ene or diethylene glycol under a nitrogen atmosphere. The structures of the new triazoles derivatives were confirmed by analytical and spectral data.

  在氮气氛下，在乙烯或二甘醇中，芳族腈与二盐酸肼或硫酸盐与过量的水合肼反应，制得了许多对称的3,5-二取代的4-氨基-1,2,4-三唑。 。通过分析和光谱数据证实了新的三唑衍生物的结构。
• Preparation of π-conjugated polymers consisting of 1-aminopyrrole and 4-amino-1,2,4-triazole units
  作者：Syusaku Koie、Gentaro Tanaka、Hiroki Fukumoto、Take-aki Koizumi、Takakazu Yamamoto

  DOI：10.1016/j.reactfunctpolym.2013.05.013

  日期：2013.9

  Abstract π-Conjugated polymers based on 1-aminopyrrole and 4-amino-1,2,4-triazole were prepared. Pd-catalyzed organometallic polycondensation gave poly(arylene-ethynylene) (PAE)-type π-conjugated polymers consisting of BOC-protected 4-amino-1,2,4-triazole ( Taz(BOC) ) units (BOC = t -butoxycarbonyl). The number average molecular weights ( M n ) were determined to be 5200–19,200 using GPC. An alternating

  摘要制备了以1-氨基吡咯和4-氨基-1,2,4-三唑为基的π共轭聚合物。Pd催化的有机金属缩聚反应得到由BOC保护的4-氨基-1,2,4-三唑（Taz（BOC））单元（BOC =叔丁氧羰基）组成的聚（亚芳基-亚乙炔基）（PAE）型π共轭聚合物。 ）。使用GPC测定的数均分子量（M n）为5200–19,200。还通过Pd催化的有机金属缩聚反应制备了Taz（BOC）和联噻吩（Th-Th）单元P（Taz（BOC）-Th-Th）n -Pd的交替共聚物，其M n为10,800。（Taz（BOC）-Th-Th）n -Pd在λmax = 425 nm处显示UV-Vis吸收峰，这对于具有共面结构的π共轭五元环聚合物是合理的。聚合物的BOC基团的脱保护反应在200°C下进行；使用模型化合物研究了BOC脱保护。报道了π共轭聚合物的光学和电化学性质。
• Non-toxic corrosion-protection pigments based on manganese
  申请人：——

  公开号：US20040011252A1

  公开（公告）日：2004-01-22

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well-founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

  以锰为基础的缓蚀颜料含有三价或四价锰/价稳定剂复合物。一种无机或有机材料可用于稳定三价或四价锰离子，从而形成一种可少量溶解、溶解度低或不溶于水的化合物，具体取决于预期用途。选择特定的稳定剂是为了控制三价锰或四价锰在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。锰/价稳定剂组合的选择是基于锰配位化学的基本原理。文中介绍了许多锰价稳定剂组合，其性能与传统的六价铬或四价铅体系相当。需要强调的是，提供本摘要是为了符合要求提供摘要的规则，以便检索者或其他读者快速确定技术公开的主题。提交本摘要的前提是，本摘要不用于解释或限制权利要求的范围或含义。
• Non-toxic corrosion-protection pigments based on rare earth elements
  申请人：——

  公开号：US20040104377A1

  公开（公告）日：2004-06-03

  A corrosion-inhibiting pigment comprising a rare earth element and a valence stabilizer combinded to form a rare earth/valence stabilizer complex. The rare earth element is selected from cerium, terbium, praseodymium, or a combination thereof, and at least one rare earth element is in the tetravalent oxidation state. An inorganic or organic material is used to stabilize the tetravalent rare earth ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of tetravalent cerium, terbium, or praseodymium during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Many rare earth-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.

  一种缓蚀颜料，由稀土元素和价态稳定剂结合形成稀土/价态稳定剂复合物。稀土元素选自铈、铽、镨或它们的组合，至少有一种稀土元素处于四价氧化态。使用无机或有机材料来稳定四价稀土离子，以形成稀溶于水的化合物。选择特定的稳定剂是为了控制四价铈、铽或镨在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。本文介绍了许多稀土-价稳定剂组合，其性能可与传统的六价铬体系媲美。
• High-Throughput Synthesis of Symmetrically 3,5-Disubstituted 4-Amino-1,2,4-triazoles from Aldehydes Using Microwave
  作者：Hideko Koshima、Mitsuo Hamada、Makiko Tani、Shunsuke Iwasaki、Fumika Sato

  DOI：10.3987/com-02-9584

  日期：——

  Symmetrically 3,5-substituted 4-amino-1,2,4-triazoles are quickly prepared from aromatic aldehydes via nitriles by two-step reactions without any separation under microwave irradiation for each several minutes.