2,3,8-三甲基喹啉 | 4945-28-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 2,3,8-三甲基喹啉
• 英文名称: 2,3,8-trimethyl-quinoline
• 英文别名: 2,3,8-Trimethyl-chinolin；NoName_3551；2,3,8-trimethylquinoline
• CAS: 4945-28-2
• 化学式: C₁₂H₁₃N
• mdl: MFCD18448977
• 分子量: 171.242
• InChiKey: SVBNPCUNVWUQOF-UHFFFAOYSA-N

物化性质

• 熔点：
  68.75°C (estimate)
• 沸点：
  286.23°C (estimate)
• 密度：
  1.0069

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,3,8-三甲基喹啉 在 chromium(VI) oxide 、 硫酸 作用下， 生成 2,3-dimethyl-quinoline-8-carboxylic acid
  参考文献：
  名称：

  The Nitrogen Compounds in Petroleum Distillates. XX. Isolation of 2-Methyl-8-ethylquinoline from California Petroleum and Proof of Structure through Degradation and Synthesis

  摘要：

  DOI：

  10.1021/ja01848a002
• 作为产物：
  描述：

  反式-2-甲基-2-丁烯醛 、 2-甲基苯胺 盐酸盐 在 盐酸 作用下， 生成 2,3,8-三甲基喹啉
  参考文献：
  名称：

  AN INVESTIGATION OF THE BASES IN THE KEROSENE DISTILLATE OF CALIFORNIA PETROLEUM¹

  摘要：

  DOI：

  10.1021/ja01366a067

文献信息

• REACTIVE COMPOUND
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150353583A1

  公开（公告）日：2015-12-10

  A reactive compound represented by the following formula (I): [In the formula (I), Z represents a divalent group. A plurality of Y may be the same or different, and represent a monovalent boronate residue having at least one hydroxyl group, Ar 1 and Ar 2 may be the same or different, and represent a trivalent aromatic hydrocarbon group or a trivalent heterocyclic group.].

  由以下公式（I）表示的一种反应性化合物： [在公式（I）中，Z代表二价基团。多个Y可以相同也可以不同，并表示至少有一个羟基的一价硼酸酯残基，Ar1和Ar2可以相同也可以不同，并表示三价芳香烃基团或三价杂环基团。]。
• HETEROCYCLIC COMPOUNDS AND THEIR USES
  申请人：Brown Matthew

  公开号：US20120094972A1

  公开（公告）日：2012-04-19

  Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

  含有替代双环杂芳基的化合物及其组合物，用于治疗一般性炎症、关节炎、风湿性疾病、骨关节炎、炎性肠道疾病、炎性眼部疾病、炎性或不稳定的膀胱疾病、牛皮癣、具有炎症成分的皮肤病、包括但不限于自身免疫性疾病，如系统性红斑狼疮（SLE）、重症肌无力、类风湿性关节炎、急性播散性脑脊髓炎、特发性血小板减少性紫癜、多发性硬化症、Sjogren综合征和自身免疫性溶血性贫血，包括所有过敏症形式的过敏症，本发明还提供了治疗介导、依赖或与p110活性相关的癌症的方法，包括但不限于白血病，如急性髓细胞白血病（AML）、骨髓增生异常综合征（MDS）、骨髓增殖性疾病（MPD）、慢性髓细胞白血病（CML）、T细胞急性淋巴细胞白血病（T-ALL）、B细胞急性淋巴细胞白血病（B-ALL）、非霍奇金淋巴瘤（NHL）、B细胞淋巴瘤和实体瘤，如乳腺癌。
• Organic photoelectric conversion element, and solar cell module and sensor provided with the same
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US11063219B2

  公开（公告）日：2021-07-13

  An object is to provide an organic photoelectric conversion element having high durability. The present invention provides an organic photoelectric conversion element having an active layer between a cathode and an anode, characterized in that, the organic photoelectric conversion element includes a layer including a cured product obtained by curing a thermosetting resin composition between the anode and the active layer, and a transmittance of light with a wavelength of 380 nm to 780 nm is 10% or higher. The present invention provides the organic photoelectric conversion element in which the thermosetting resin composition includes one or more selected from the group consisting of polythiophene and derivatives thereof and a polymer compound including a repeating unit having an aromatic amine residue.

  目的是提供一种具有高耐久性的有机光电转换元件。本发明提供了一种有机光电转换元件，该元件在阴极和阳极之间具有一个活性层，其特征在于，该有机光电转换元件包括一个层，该层包括通过固化阳极和活性层之间的热固性树脂组合物而获得的固化产物，波长为 380 纳米至 780 纳米的光的透射率为 10%或更高。本发明提供的有机光电转换元件中，热固性树脂组合物包括一种或多种选自聚噻吩及其衍生物和包括具有芳香族胺残基的重复单元的聚合物化合物组成的组。
• Manske et al., Canadian Journal of Research, Section B: Chemical Sciences, vol. 20, p. 1942 133, 144
  作者：Manske et al.

  DOI：——

  日期：——
• Petroleum Bases. I. Reactions of 2,3,8-Trimethylquinoline
  作者：Alfred Burger、Luther R. Modlin

  DOI：10.1021/ja01862a024

  日期：1940.5