1-吖啶-9-基-乙酮 | 16600-44-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 1-吖啶-9-基-乙酮
• 英文名称: 9-Acetyl-acridin
• 英文别名: 1-(Acridin-9-yl)ethan-1-one；1-acridin-9-ylethanone
• CAS: 16600-44-5
• 化学式: C₁₅H₁₁NO
• 分子量: 221.258
• InChiKey: DWQJITQAAAQGGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-吖啶-9-基-乙酮 在 水 、 氢溴酸 、 溴 作用下， 生成 1-吖啶-9-基-2-溴-乙酮
  参考文献：
  名称：

  Eisleb, 1936, vol. 3, p. 41,48

  摘要：

  DOI：
• 作为产物：
  描述：

  1-吖啶-9-基-2-溴-乙酮 在 二乙胺 、 苯 作用下， 生成 1-吖啶-9-基-乙酮
  参考文献：
  名称：

  Bras; Kore, Zhurnal Obshchei Khimii, 1953, vol. 23, p. 868,872,873;engl.Ausg.S.909,912,913

  摘要：

  DOI：

文献信息

• Iron-Catalyzed Minisci Type Acetylation of <i>N</i> -Heteroarenes Mediated by CH(OEt)₃ /TBHP
  作者：A. Srinivasulu、B. Shantharjun、D. Vani、K. Chinna Ashalu、A. Mohd、J. Wencel-Delord、F. Colobert、K. Rajender Reddy

  DOI：10.1002/ejoc.201900033

  日期：2019.2.28

  Iron-catalyzed acetylation of electron deficient N-heteroarenes has been reported using triethylorthoformate as robust and inexpensive acetyl source. This new method is successfully applied for the acetylation of quinolines, isoquinoline, quinoxalines, arylpyridines, bipyridines, and benzothiazole.

  据报道，铁催化的缺电子 N-杂芳烃乙酰化使用原甲酸三乙酯作为稳定且廉价的乙酰源。这种新方法已成功应用于喹啉、异喹啉、喹喔啉、芳基吡啶、联吡啶和苯并噻唑的乙酰化反应。
• Eisleb, 1936, vol. 3, p. 41,47
  作者：Eisleb

  DOI：——

  日期：——
• FACILE N-ALKYLATION OF ACRIDINE COMPOUNDS IN IONIC LIQUIDS
  申请人：Natrajan Anand

  公开号：US20100256380A1

  公开（公告）日：2010-10-07

  A method is provided for N-alkylation of acridine compounds, typically with a 1,3-propane sultone alkylating reagent, in ionic liquid solvents to provide the corresponding acridinium compounds in high yield.
• Method for selectively binding a substrate to sorbents by way of at least bivalent bonds
  申请人：Gottschall Klaus

  公开号：US20110257028A1

  公开（公告）日：2011-10-20

  A method for the manufacture of at least one sorbent having at least two different groups, which are capable of binding, for the selective binding of a substrate, characterized in that it comprises the steps (i) to (ii): (i) determining at least two groups capable of binding a sorbent from a synthetic or natural first substrate, (ii) respectively applying at least two different groups capable of binding a second synthetic or natural substrate to one respective carrier, thereby forming at least one sorbent, whereby the groups are the same groups of step (i) or are groups that are complementary thereto, and the second substrate of step (ii) is the same or different from the first substrate according to step (i), and whereby the groups are determined such that the contributions of the Gibbs energies of the individual groups to the non-covalent bond with the second substrate yield a negative value of the Gibbs energy ΔG, such that a binding strengthening occurs that results in an improved separation selectivity with respect to at least one substance to be separated off.
• US8293908B2
  申请人：——

  公开号：US8293908B2

  公开（公告）日：2012-10-23