2,2,6-trimethyl-1-methylenecyclohexane | 40514-66-7

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 2,2,6-trimethyl-1-methylenecyclohexane
• 英文别名: 2,2,6-Trimethyl-methylencyclohexan；1,1,3-trimethyl-2-methylene-cyclohexane；1,1,3-Trimethyl-2-methylen-cyclohexan；1,1,3-trimethyl-2-methylidene-cyclohexane；1,1,3-Trimethyl-2-methylidenecyclohexane
• CAS: 40514-66-7
• 化学式: C₁₀H₁₈
• 分子量: 138.253
• InChiKey: WVCGHSCRZZMFMZ-UHFFFAOYSA-N

物化性质

• 沸点：
  55-60 °C(Press: 11 Torr)
• 密度：
  0.8160 g/cm3(Temp: 22 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2902199090

反应信息

• 作为反应物：
  描述：

  2,2,6-trimethyl-1-methylenecyclohexane 在 臭氧 作用下， 以 乙醚 为溶剂， 以56%的产率得到2,2,6-三甲基环己酮
  参考文献：
  名称：

  1-烷基取代的1-叔丁基乙烯和高度甲基化的亚甲基环烷烃的臭氧分解。取代基的空间体积对伯氮氧化物裂解方向的影响

  摘要：

  在醚中在三氟苯乙酮（7）存在下进行1-烷基取代的1-叔丁基乙烯和高度甲基化的亚甲基环烷烃的臭氧分解。2,2,6-三甲基-1-亚甲基环己烷的臭氧分解仅提供了用酮7捕获甲醛O-氧化物而获得的交叉臭氧化物10，产率为42％，而在相关2,2,5的情况下-三甲基-1-亚甲基环戊烷-由2,7,5-三甲基环戊酮O-氧化物与酮7加成环而获得的另一种交叉-臭氧化物15e是唯一可隔离的产品。两种可能的裂环作用过程的用于初级臭氧化物的总能量12C和12E，在B3LYP / 6-31G计算** // B3LYP / 3-21G *水平的理论，似乎重现碎片之间的区域化学所观察到的差异这两个主要的臭氧化物。

  DOI：

  10.1016/s0040-4020(01)01183-8
• 作为产物：
  描述：

  C-(2,2,6-trimethyl-cyclohexyl)-methylamine 在 溶剂黄146 、 sodium nitrite 作用下， 生成 2,2,6-trimethyl-1-methylenecyclohexane 、 1,4,4-trimethylcycloheptene
  参考文献：
  名称：

  塞隆·德马诺（Selon Demjanow）

  摘要：

  LA比例D'hydrocarbures魁accompagne乐cyclocitronellol和les三甲基cyeloheptanols lorsqu'on贴花拉réctionD'扩展cyelique德Demjanow点菜二氢cyclogéranylamine，contient，à科特迪瓦德三甲基1,1,4-cycloheptènes，杜亚甲基2-三甲基-1,1,3-环己烷。

  DOI：

  10.1002/hlca.19430260507

文献信息

• Organic reactions at high pressure. Wittig reaction of hindered ketones with nonstabilized ylides.
  作者：William G. Dauben、James J. Takasugi

  DOI：10.1016/s0040-4039(00)96514-6

  日期：1987.1

  The Wittig reaction between n-butylidenetriphenylphosphorane and a series of cyclohexanones of increasing steric hindrance around the carbonyl group has been studied at 7 kbar and 15 kbar pressure (0.75–1.5 GPa) and at 40 °C. In all cases, except 2,2,6,6-tetramethylcyclohexanone and fenchone, 45-60% yields of olefins were obtained, in contrast to poor to no yields which were obtained under ambient

  在7 kbar和15 kbar的压力（0.75–1.5 GPa）和40°C的条件下，研究了正丁基亚乙基三苯基磷烷与一系列围绕羰基的位阻增加的环己酮之间的维蒂希反应。在所有情况下，除了2,2,6,6-四甲基环己酮和Fenchone，均能获得45-60％的烯烃收率，与之相比，在环境条件下收率很低甚至没有。
• Characterization of Indoor Particle Sources Using Continuous Mass and Size Monitors
  作者：Christopher M. Long、Helen H. Suh、Petros Koutrakis

  DOI：10.1080/10473289.2000.10464154

  日期：2000.7

  A comprehensive indoor particle characterization study was conducted in nine Boston-area homes in 1998 in order to characterize sources of PM in indoor environments. State-of-the-art sampling methodologies were used to obtain continuous PM2.5 concentration and size distribution particulate data for both indoor and outdoor air. Study homes, five of which were sampled during two seasons, were monitored over week-long periods. Among other data collected during the extensive monitoring efforts were 24-hr elemental/organic carbon (EC/OC) particulate data as well as semi-continuous air exchange rates and time-activity information.This rich data set shows that indoor particle events tend to be brief, intermittent, and highly variable, thus requiring the use of continuous instrumentation for their characterization. In addition to dramatically increasing indoor PM2.5 concentrations, these data demonstrate that indoor particle events can significantly alter the size distribution and composition of indoor particles. Source event data demonstrate that the impacts of indoor activities are especially pronounced in the ultrafine (d(a) less than or equal to 0.1 mu m) and coarse (2.5 less than or equal to d(a) less than or equal to 10 mu m) modes. Among the sources of ultrafine particles characterized in this study are indoor ozone/terpene reactions. furthermore, EC/OC data suggest that organic carbon is a major constituent of particles emitted during indoor source events. Whether exposures to indoor-generated particles, particularly from large short-term peak events, may be associated with adverse health effects will become clearer when biological mechanisms are better known.
• Synthesis of alkenes with P-(α-lithioalkyl)phosphinothioic amides
  作者：Carl R. Johnson、Robert C. Elliott

  DOI：10.1021/ja00389a026

  日期：1982.12
• Extension de cycles dans la série hydroaromatique. II. Essais avec la 1,1, 3-triméthyl-cyclohexyl-méthylamine-2 (Dihydro-cyclogéranyl-méthylamine)
  作者：Henri Barbier

  DOI：10.1002/hlca.19400230169

  日期：——
• Cyanogen azide ring-expansion reaction
  作者：John E. McMurry、Anthony P. Coppolino

  DOI：10.1021/jo00956a019

  日期：1973.8