3,4-dihydroxy-4-methyl-pentan-2-one | 85933-26-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-dihydroxy-4-methyl-pentan-2-one
• 英文别名: 3,4-Dihydroxy-4-methyl-pentan-2-on；Methyl-(α.β-dioxy-isobutyl)-keton；α.α-Dimethyl-α'-acetyl-aethylenglykol；γ.δ-Dioxy-β-oxo-δ-methyl-pentan；2-Methyl-pentandiol-(2.3)-on-(4)；Dioxydihydromesityloxyd；3,4-Dihydroxy-4-methyl-2-pentanone；3,4-dihydroxy-4-methylpentan-2-one
• CAS: 85933-26-2
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: OSPIOFUQWMUWOI-UHFFFAOYSA-N

物化性质

• 沸点：
  99-100 °C(Press: 12 Torr)
• 密度：
  1.0809 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,4-dihydroxy-4-methyl-pentan-2-one 生成 羟基丙酮 、 丙酮
  参考文献：
  名称：

  Harries; Pappos, Chemische Berichte, 1901, vol. 34, p. 2979

  摘要：

  DOI：
• 作为产物：
  描述：

  4-甲基-3戊烯-2-酮 在 锇 、 Cu-Al-hydrotalcite 水 、 N-甲基吗啉氧化物 作用下， 以 甲苯 为溶剂， 反应 6.0h， 以100%的产率得到3,4-dihydroxy-4-methyl-pentan-2-one
  参考文献：
  名称：

  The Os/Cu–Al-hydrotalcite catalysed hydroxylation of alkenes

  摘要：

  一种新型Os/Cu-Al-水滑石类催化剂被描述，其与N-甲基氧化吗啉作为共氧化剂，能够在异相催化下选择性地高产率地将烯烃羟基化生成二醇。

  DOI：

  10.1039/b310686a

文献信息

• Catalytic Hydroxylation of Olefins by Polymer-Bound Osmium Tetroxide
  作者：Gianfranco Cainelli、Michele Contento、Francesco Manescalchi、Laura Plessi

  DOI：10.1055/s-1989-27145

  日期：——

  Osmium tetroxide, linked to insoluble crosslinked polymers and copolymers bearing tertiary amino functions, has been used in the presence of secondary oxidants, such as hydrogen peroxide, tert-butyl hydroperoxide and trimethylamine N-oxide, to accomplish the catalytic hydroxylation of olefins. The polymeric reagent offers the advantages of easy and safe handling, and simple separation from the reaction medium. Generally good yields of vicinal diols have been obtained.

  四氧化锇与具有三级氨基功能的不可溶交联聚合物和共聚物相结合，在次级氧化剂（如过氧化氢、叔丁基过氧化氢和N-氧化三甲基胺）的 presence 中被用于催化烯烃的羟基化。聚合物试剂提供了易于安全操作和简单从反应介质中分离的优点。通常获得了较好的邻二醇产率。
• Nasarow; Achrem, Zhurnal Obshchei Khimii, 1950, vol. 20, p. 2183,2186, 2190;engl. Ausg. S. 2267, 2270, 2274
  作者：Nasarow、Achrem

  DOI：——

  日期：——
• Pastureau; Bernard, Bulletin de la Societe Chimique de France, 1923, vol. <4>33, p. 1450
  作者：Pastureau、Bernard

  DOI：——

  日期：——
• Microstructural Control of a 70% Silicon Nitride- 30% Barium Aluminum Silicate Self-Reinforced Composite
  作者：Feng Yu、Nandakumar Nagarajan、Yi Fang、Kenneth W. White

  DOI：10.1111/j.1151-2916.2001.tb00601.x

  日期：2001.1

  The processing response of a 70% silicon nitride–30% barium aluminum silicate (70%‐Si3N4–30%‐BAS) ceramic‐matrix composite was studied using pressureless sintering, at temperatures ranging from 1740°C, which is below the melting point of BAS, to 1950°C. The relationship between the processing parameters and the microstructural constituents, such as morphology of the β‐Si3N4 whisker and crystallization of the BAS matrix, was evaluated. The mechanical response of this array of microstructures was characterized for flexural strength, as well as fracture behavior, at test temperatures up to 1300°C. The indentation method was used to estimate the fracture resistance, and R‐curves were obtained from modified compact‐tension samples of selected microstructures at room temperature.
• Slawinski, Chemisches Zentralblatt, 1918, vol. 89, # I, p. 915
  作者：Slawinski

  DOI：——

  日期：——