(8-methylindolizine-1,2,3-triyl)tris(phenylmethanone) | 1393956-24-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (8-methylindolizine-1,2,3-triyl)tris(phenylmethanone)
• 英文别名: (2,3-Dibenzoyl-8-methylindolizin-1-yl)-phenylmethanone；(2,3-dibenzoyl-8-methylindolizin-1-yl)-phenylmethanone
• CAS: 1393956-24-5
• 化学式: C₃₀H₂₁NO₃
• 分子量: 443.502
• InChiKey: UYNDTJWQHCIWPX-UHFFFAOYSA-N

物化性质

• 密度：
  1.18±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  55.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-甲基吡啶 、 苯乙酮 在 碘 、 二甲基亚砜 作用下， 反应 36.0h， 生成 (8-methylindolizine-1,2,3-triyl)tris(phenylmethanone) 、 (6-methylindolizine-1,2,3-triyl)tris(phenylmethanone)
  参考文献：
  名称：

  Convergent domino synthesis of 1,2,3-triaroylindolizines from methyl ketones and pyridines via self-division of labor strategy

  摘要：

  A highly efficient method for the synthesis of 1,2,3-triaroylindolizines has been established from readily available methyl ketones and pyridines in the presence of iodine. This reaction also examplified the self-division of labor strategy in convergent domino synthesis. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.06.091

文献信息

• Convergent domino synthesis of 1,2,3-triaroylindolizines from methyl ketones and pyridines via self-division of labor strategy
  作者：Yan Yang、Meng Gao、Dong-Xue Zhang、Liu-Ming Wu、Wen-Ming Shu、An-Xin Wu

  DOI：10.1016/j.tet.2012.06.091

  日期：2012.9

  A highly efficient method for the synthesis of 1,2,3-triaroylindolizines has been established from readily available methyl ketones and pyridines in the presence of iodine. This reaction also examplified the self-division of labor strategy in convergent domino synthesis. (C) 2012 Elsevier Ltd. All rights reserved.