chrysin dihexanoate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: chrysin dihexanoate
• 英文别名: (5-Hexanoyloxy-4-oxo-2-phenylchromen-7-yl) hexanoate
• 化学式: C₂₇H₃₀O₆
• 分子量: 450.532
• InChiKey: SOBCIZZIYCQRCU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  33
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  chrysin dihexanoate 在 咪唑 、 苯硫酚 作用下， 以 N-甲基吡咯烷酮 为溶剂， 以93%的产率得到5-O-hexanoylchrysin
  参考文献：
  名称：

  Facile Synthesis of Flavonoid 7-O-Glycosides

  摘要：

  Highly regioselective removal of the 7-O-acylgroups of the peracyated flavones, isoflavones, and flavonolsyl(PhSH, imidazole, NMP) followed by effective glycosylation with glycosyl trifluoroacetimidates (BF3.Et2O) and cautious deprotection of the acyl groups under basic conditions afforded the desired 7-O-flavonoid glycosides in satisfactory yields.

  DOI：

  10.1021/jo034553e
• 作为产物：
  描述：

  白杨素 、 己酰氯 在 吡啶 作用下， 以87%的产率得到chrysin dihexanoate
  参考文献：
  名称：

  Facile Synthesis of Flavonoid 7-O-Glycosides

  摘要：

  Highly regioselective removal of the 7-O-acylgroups of the peracyated flavones, isoflavones, and flavonolsyl(PhSH, imidazole, NMP) followed by effective glycosylation with glycosyl trifluoroacetimidates (BF3.Et2O) and cautious deprotection of the acyl groups under basic conditions afforded the desired 7-O-flavonoid glycosides in satisfactory yields.

  DOI：

  10.1021/jo034553e

文献信息

• Facile Synthesis of Flavonoid 7-<i>O</i>-Glycosides
  作者：Ming Li、Xiuwen Han、Biao Yu

  DOI：10.1021/jo034553e

  日期：2003.8.1

  Highly regioselective removal of the 7-O-acylgroups of the peracyated flavones, isoflavones, and flavonolsyl(PhSH, imidazole, NMP) followed by effective glycosylation with glycosyl trifluoroacetimidates (BF3.Et2O) and cautious deprotection of the acyl groups under basic conditions afforded the desired 7-O-flavonoid glycosides in satisfactory yields.