α-hydroxy-3,3-dimethyl-2-butyl phenyl ketone | 124287-54-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-hydroxy-3,3-dimethyl-2-butyl phenyl ketone
• 英文别名: 2-Hydroxy-2,3,3-trimethyl-1-phenyl-1-butanone；2-hydroxy-2,3,3-trimethyl-1-phenylbutan-1-one
• CAS: 124287-54-3
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: TUZAYEWZIXWTER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  α-hydroxy-3,3-dimethyl-2-butyl phenyl ketone 在 三氟甲磺酸 作用下， 以 二氯甲烷 为溶剂， 反应 16.0h， 以78%的产率得到3,3-Dimethyl-2-methylene-1-phenyl-butan-1-one
  参考文献：
  名称：

  Trifluoromethanesulfonic (triflic) acid catalyzed transformations of .alpha.-hydroxy carbonyl compounds

  摘要：

  Triflic acid catalyzed reaction of 2-hydroxy-2-adamantanecarboxylic acid results via ionizative decarbonylation in the formation of adamantonone. Under carbon monoxide pressure pinacol-type rearrangement gives 4,5-homoadamantanedione. Reaction of a series of alpha-hydroxy ketones result in fragmentation, deprotonation, and cyclization, respectively. The reactions and their suggested mechanism are discussed.

  DOI：

  10.1021/jo00007a048
• 作为产物：
  描述：

  频哪酮 在 sodium acetate 、 lithium diisopropyl amide 作用下， 反应 3.0h， 生成 α-hydroxy-3,3-dimethyl-2-butyl phenyl ketone
  参考文献：
  名称：

  Trifluoromethanesulfonic (triflic) acid catalyzed transformations of .alpha.-hydroxy carbonyl compounds

  摘要：

  Triflic acid catalyzed reaction of 2-hydroxy-2-adamantanecarboxylic acid results via ionizative decarbonylation in the formation of adamantonone. Under carbon monoxide pressure pinacol-type rearrangement gives 4,5-homoadamantanedione. Reaction of a series of alpha-hydroxy ketones result in fragmentation, deprotonation, and cyclization, respectively. The reactions and their suggested mechanism are discussed.

  DOI：

  10.1021/jo00007a048

文献信息

• A new access to acyl- and aroyllithiums via lithium-tellurium exchange
  作者：Tomoki Hiiro、Yoshiyuki Morita、Toru Inoue、Nobuaki Kambe、Akiya Ogawa、Ilhyong Ryu、Noboru Sonoda

  DOI：10.1021/ja00157a074

  日期：1990.1

  La reaction de derives de tellurobenzoates de Te-butyle avec le butyl lithium puis avec differents electrophiles (dimethyl-3,3 butanone-2 ou dimethyl-2,2 propanal) donnent des derives d'hydroxy-2 trimethyl-2,3,3 butyrophenone ou d'hydroxy-4 tetramethyl-2,2,5,5 hexanone-3

  La 反应 de 派生 de 碲苯甲酸盐 de Te-butyle avec le 丁基锂 puis avec 不同的亲电试剂 (二甲基-3,3 丁酮-2 或二甲基-2,2 丙醛) donnent des 派生 d'hydroxy-2 trimethyl-2,3,3 butyrophenone ou d'hydroxy-4 tetramethyl-2,2,5,5 hexanone-3
• OLAH, GEORGE A.;WU, AN-HSIANG, J. ORG. CHEM., 56,(1991) N, C. 2531-2534
  作者：OLAH, GEORGE A.、WU, AN-HSIANG

  DOI：——

  日期：——
• POLYMERISATION PROCESS
  申请人：Ciba Specialty Chemicals Water Treatments Limited

  公开号：EP1368382A1

  公开（公告）日：2003-12-10
• Polymerisation process
  申请人：——

  公开号：US20040077744A1

  公开（公告）日：2004-04-22

  A process of preparing water soluble or water swellable polymer comprising the steps: a) forming an aqueous mixture comprising, i) a water soluble ethylenically unsaturated monomer or blend of monomers and, ii) at least one first ultra-violet initiator, iii) at least one second ultra-violet initiator; b) effecting polymerisation by subjecting the aqueous mixture formed in step (a) to irradiation by ultraviolet light at an intensity of up to 1,000 &mgr;Wcm −2 ; subjecting the product of step (b) to irradiation by ultraviolet light of greater than 1,000 &mgr;Wcm −2 , characterised in that a significant amount of the first initiator(s) is/are activated in step (b) and a significant amount of the second initiator(s) is/are activated in step (c). The process is particularly suitable for making highly effective water soluble and water swellable polymers useful as flocculants, coagulants, rheology modifiers, dispersants, superabsorbents and binders etc.
• US4547394A
  申请人：——

  公开号：US4547394A

  公开（公告）日：1985-10-15