十二烷异丙基醚 | 29379-42-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 十二烷异丙基醚
• 英文名称: n-dodecyl isopropyl ether
• 英文别名: Ether, dodecyl isopropyl；1-propan-2-yloxydodecane
• CAS: 29379-42-8
• 化学式: C₁₅H₃₂O
• 分子量: 228.418
• InChiKey: JYJHLFUHTHWNSJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  16
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909199090

反应信息

• 作为反应物：
  描述：

  十二烷异丙基醚 、 alkaline earth salt of/the/ methylsulfuric acid 、 alkaline earth salt of/the/ methylsulfuric acid 生成 月桂酸 、 月桂酸异丙酯 、 异丙醇 、 丙酮
  参考文献：
  名称：

  Reactions of Unsaturated Fatty Alcohols. IV. Oxidative Degradation of Lauryl Isopropyl Ether¹

  摘要：

  DOI：

  10.1021/jo01084a004
• 作为产物：
  描述：

  1-(prop-1-en-2-yloxy)dodecane 在 镍 氢气 作用下， 生成 十二烷异丙基醚
  参考文献：
  名称：

  Mastagli,P. et al., Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1963, vol. 257, p. 690 - 692

  摘要：

  DOI：

文献信息

• A mild and simple procedure for the reductive cleavage of acetals and ketals
  作者：Adusumilli Srikrishna、Ranganathan Viswajanani

  DOI：10.1016/0040-4020(95)00055-d

  日期：1995.3

  A convenient, mild and simple procedure, employing sodium cyanoborohydride in the presence of either catalytic or stoichiometric amount of boron trifluoride etherate in dry THF, for the reductive cleavage of the acetals and ketals is described.

  描述了一种方便，温和且简单的方法，该方法在催化或化学计量的三氟化硼醚化物在干燥THF中的存在下使用氰基硼氢化钠进行缩醛和缩酮的裂解。
• COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM
  申请人：Takayama Masami

  公开号：US20090318513A1

  公开（公告）日：2009-12-24

  A compound represented by the general formula (I): wherein R 1 is a hydrogen atom, a halogen atom, or the like; R 2 , R 3 , and R 4 are each independently a hydrogen atom, a halogen atom, C1-C15 alkyl optionally substituted with one or more C1-C12 alkyloxy or the like, or the like; R 5 is a hydrogen atom or the like; R 6 and R 7 are a hydrogen atom or the like; R 8 is C1-C3 alkyl or the like; R 9 is a hydrogen atom or the like), a prodrug, a pharmaceutically acceptable salt, or solvate thereof.

  一种由通式（I）表示的化合物：其中R1是氢原子、卤素原子或类似物；R2、R3和R4各自独立地是氢原子、卤素原子、C1-C15烷基（可选地用一个或多个C1-C12烷氧基或类似物取代）或类似物；R5是氢原子或类似物；R6和R7是氢原子或类似物；R8是C1-C3烷基或类似物；R9是氢原子或类似物。该化合物为一种前药、药物可接受的盐或其溶剂。
• Compounds exhibiting thrombopoietin receptor agonism
  申请人：Takayama Masami

  公开号：US20070043087A1

  公开（公告）日：2007-02-22

  A compound represented by the general formula (I): wherein R 1 is a hydrogen atom, a halogen atom, or the like; R 2 , R 3 , and R 4 are each independently a hydrogen atom, a halogen atom, C1-C15 alkyl optionally substituted with one or more C1-C12 alkyloxy or the like, or the like; R 5 is a hydrogen atom or the like; R 6 and R 7 are a hydrogen atom or the like; R 8 is C1-C3 alkyl or the like; R 9 is a hydrogen atom or the like), a prodrug, a pharmaceutically acceptable salt, or solvate thereof.

  化合物的一般式(I)表示的复合物，其中R1是氢原子、卤素原子或类似物；R2、R3和R4各自独立地是氢原子、卤素原子、C1-C15烷基（可选地用一个或多个C1-C12烷氧基或类似物取代）或类似物；R5是氢原子或类似物；R6和R7是氢原子或类似物；R8是C1-C3烷基或类似物；R9是氢原子或类似物。这是一个前药、药物可接受的盐或其溶剂。
• High yield carbonylation of halo-hydrocarbons
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0222460A1

  公开（公告）日：1987-05-20

  High yields of aromatic, aromatic acetic and olefinic acids, esters, amides and the like are derived from a pro­cess wherein a halo-hydrocarbon is carbonylated in the pres­ence of a palladium catalyst, a hindered amine base and phosphine in excess. The hindered amine base can comprise C₃-C₁₀ branched alkyls, cyclic compounds, or mixtures of the above. The preferred amine is N,N-diisopropylethyl amine. The preferred catalyst is PdCl₂(PPH₃)₂ with the excess phos­phine generally supplied by a compound of the formula PR¹R²R³ where R¹,R² and R³ are preferably phenyl.

  高产率的芳香族、芳香族乙酸和烯烃酸、酯、酰胺等可通过以下工艺制得：卤代烃在钯催化剂、受阻胺碱和过量膦的存在下发生羰基化反应。受阻胺基可包括 C₃-C₁₀ 支链烷基、环状化合物或上述物质的混合物。首选胺为 N,N-二异丙基乙基胺。优选催化剂为 PdCl₂(PPH₃)₂，过量的膦通常由式 PR¹R²R³ 的化合物提供，其中 R¹、R² 和 R³ 优选为苯基。
• Single phase carbonylation of aromatic halides to carboxylic acid salts
  申请人：STAUFFER CHEMICAL COMPANY

  公开号：EP0273553A1

  公开（公告）日：1988-07-06

  A process for preparing carboxylic acid salts by the reaction of carbon monoxide with substituted or unsubstituted aromatic halides or an aliphatic organic halide comprises the catalyst single phase carbonylation of the halide utilizing in addition to carbon monoxide, a palladium catalyst, an excess of tertiary phosphine, optionally an amine compound, with an alkali metal or alkaline earth metal base added during the reaction to form the salt.

  一种通过一氧化碳与取代或未取代的芳香族卤化物或脂肪族有机卤化物反应制备羧酸盐的工艺，包括卤化物的催化剂单相羰基化，除一氧化碳外，还利用钯催化剂、过量的叔膦，可选择胺化合物，在反应过程中加入碱金属或碱土金属碱，以形成盐。