1,3,5-三(4-氨基苯氧基)苯 | 102852-92-6

• 物质功能分类: 生物 - 细胞培养 - 添加剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,3,5-三(4-氨基苯氧基)苯
• 英文名称: 1,3,5-tris(4'-aminophenoxy)benzene
• 英文别名: 1,3,5-tris(4'-aminophenyloxy)benzene；1,3,5-Tris(4-aminophenoxy)benzene；4-[3,5-bis(4-aminophenoxy)phenoxy]aniline
• CAS: 102852-92-6
• 化学式: C₂₄H₂₁N₃O₃
• 分子量: 399.449
• InChiKey: PAPDRIKTCIYHFI-UHFFFAOYSA-N

物化性质

• 熔点：
  88-90 °C
• 沸点：
  618.7±55.0 °C(Predicted)
• 密度：
  1.296±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  106
• 氢给体数：
  3
• 氢受体数：
  6

安全信息

• 危险性防范说明：
  P280,P305+P351+P338
• 危险性描述：
  H302
• 储存条件：
  存放于惰性气体中，避免接触空气。

反应信息

• 作为反应物：
  描述：

  1,3,5-三(4-氨基苯氧基)苯 、 异氰酸苯酯 以 1,2-二氯乙烷 为溶剂， 反应 10.0h， 以89%的产率得到1-[4-[3,5-Bis[4-(phenylcarbamoylamino)phenoxy]phenoxy]phenyl]-3-phenylurea
  参考文献：
  名称：

  EP2332906

  摘要：

  公开号：
• 作为产物：
  描述：

  间苯三酚 在 palladium 10% on activated carbon 、 氢气 、 potassium carbonate 作用下， 以 水 、 乙酸乙酯 、 N,N-二甲基甲酰胺 为溶剂， 反应 90.0h， 生成 1,3,5-三(4-氨基苯氧基)苯
  参考文献：
  名称：

  多价可光交联的含香豆素的聚苯并恶嗪，具有增强的热和疏水表面性能†

  摘要：

  在这项研究中，通过4-甲基-7-羟基香豆素和多聚甲醛分别与苯胺，双酚A-NH 2和1,3,5-三（4-氨基苯）在1,4-二恶烷中共存。1 H和13C核磁共振（NMR），傅立叶变换红外（FTIR）和高分辨率质谱支持这三种苯并恶嗪单体的化学结构。使用差示扫描量热法（DSC）和FTIR光谱研究单，双和三香豆素BZ的香豆素单元的固化聚合行为和光二聚化（[2π+2π]环加成）以形成聚（单香豆素） BZ），聚（香豆素BZ）和聚（三香豆素BZ）。DSC测量表明，含香豆素的苯并恶嗪单体的热聚合温度低于模型化合物3-苯基-3,4-二氢-2 H的热聚合温度。-苯并恶嗪（263°C），其归因于香豆素部分的催化作用和香豆素单元中的强吸电子共轭电子C C键。另外，聚（三香豆素BZ）的玻璃化转变温度和热分解温度（T g = 240°C; T d5= 370°C）高于聚（双香豆素BZ）和聚（单香豆素BZ），这与前者较高

  DOI：

  10.1039/c5ra27705a

文献信息

• Improved Acid Resistance of a Metal–Organic Cage Enables Cargo Release and Exchange between Hosts
  作者：Lin Xu、Dawei Zhang、Tanya K. Ronson、Jonathan R. Nitschke

  DOI：10.1002/anie.202001059

  日期：2020.5.4

  vertices. The acid stability of 1 was found to be greater than that of the analogous tetrahedron 2 built from 2-formylpyridine. Intriguingly, the peripheral presence of additional pyridine rings in 1 resulted in distinct guest binding behavior from that of 2, affecting guest scope as well as binding affinities. The different stabilities and guest affinities of capsules 1 and 2 enabled the design of

  介绍了二（2-吡啶基）酮在亚组分自组装中的应用。当与柔性三胺和双（三氟甲磺酰基）酰亚胺锌结合时，该酮形成一个新的Zn4 L4四面体1，在其金属离子顶点周围带有十二个未配位的吡啶基单元。发现1的酸稳定性大于由2-甲酰基吡啶构建的类似四面体2的酸稳定性。有趣的是，1中额外存在的吡啶环的外围存在导致宾客与2的宾客行为不同，从而影响宾客范围和结合亲和力。舱室1和舱室2的不同稳定性和宾客亲和力使系统的设计成为可能，其中可以使用酸和碱作为化学刺激物在笼子之间移动不同的货物。
• Regioselective Radical Arylation of Aromatic Diamines with Arylhydrazines
  作者：Toshihide Taniguchi、Takumi Mizuno、Mitsutaka Imoto、Motonori Takeda、Takeo Nakai、Masatoshi Mihara、Akihiro Nomoto、Akiya Ogawa

  DOI：10.1055/s-0036-1588921

  日期：——

  aerospace materials, for example, Kapton®. The arylation of aromatic diamines with arylhydrazine hydrochlorides was achieved in reasonable yields. This new and simple reaction occurred at room temperature in air using an inexpensive base. This transformation seems to proceed via a homolytic aromatic substitution (HAS) mechanism. The synthesized aromatic diamines are used as raw materials for polyimides, including

  摘要 以合理的收率实现了芳基二胺与芳基肼盐酸盐的芳基化。使用便宜的碱，这种新的简单反应在室温下于空气中发生。这种转变似乎是通过均溶芳族取代（HAS）机制进行的。将合成的芳族二胺被用作聚酰亚胺的原料，包括重要的航空材料，例如，卡普顿®。 以合理的收率实现了芳基二胺与芳基肼盐酸盐的芳基化。使用便宜的碱，这种新的简单反应在室温下于空气中发生。这种转变似乎是通过均溶芳族取代（HAS）机制进行的。将合成的芳族二胺被用作聚酰亚胺的原料，包括重要的航空材料，例如，卡普顿®。
• Multi-armed, TEMPO-functionalized unimolecular initiators for starburst dendrimer synthesis via stable free radical polymerisation. 2. Tris (1,3,5)benzyloxy unimers
  作者：Mohmad Asri Abd Ghani、Dalia Abdallah、Peter M Kazmaier、Barkev Keoshkerian、Erwin Buncel

  DOI：10.1139/v04-106

  日期：2004.9.1

  The synthesis of the trifunctionalized TEMPO-modified unimolecular initiators, unimers I, II, and III is described. Unimer I was prepared via an S_N2 type Williamson ether coupling of 1,3,5-tris(iodomethyl)benzene with a TEMPO-containing ethylbenzene hydroxy derivative. The synthesis of unimer II, however, was accomplished through S_N1 reaction of 1,3,5-tris(bromomethyl)benzene with the hydroxy-ethylbenzene TEMPO derivative in the presence of silver triflate. Synthesis of unimer III started from phloroglucinol and an S_NAr reaction with 1-fluoro-4-nitrobenzene, followed by reduction to the amino compound and Schiff base formation with the TEMPO-derivatized aromatic aldehyde. Stable free radical polymerisation (SFRP) of styrene and acetoxystyrene with unimer I are also described with molecular weights and polydispersities reported. It is concluded that the SFRP of styrene with a triradical initiator meets the requirements of a living system.Key words: stable free radical polymerisation, starburst dendrimer, multi-armed unimolecular initiators.

  描述了三官能TEMPO修饰的单分子引发剂unimers I、II和III的合成。通过1,3,5-三(iodomethyl)苯与含有TEMPO的乙基苯羟基衍生物进行SN2型Williamson醚偶联来制备Unimer I。然而，Unimer II的合成是通过1,3,5-三(bromomethyl)苯与含有羟基乙基苯TEMPO衍生物在三氟乙酸银存在下进行SN1反应实现的。Unimer III的合成始于phloroglucinol和与1-氟-4-硝基苯进行SNAr反应，随后还原为氨基化合物并与TEMPO衍生的芳香醛形成席夫碱。还描述了使用Unimer I对苯乙烯和乙酰氧基苯乙烯进行稳定自由基聚合（SFRP），并报告了分子量和多分散性。总结认为，使用三重自由基引发剂对苯乙烯进行SFRP符合活性体系的要求。关键词：稳定自由基聚合，星芒状树脂，多臂单分子引发剂。
• Multi-armed, TEMPO-functionalized unimolecular initiators for starburst dendrimer synthesis via stable free radical polymerization. 1. Tri azo-functionalized unimer
  作者：Dalia Abdallah、Mohmad Asri Abd Ghani、Michael F Cunningham、Peter M Kazmaier、Barkev Keoshkerian、Erwin Buncel

  DOI：10.1139/v04-107

  日期：2004.9.1

  The synthesis of azobenzene-functionalized multi-armed unimolecular initiators or "unimers" that can be polymerized using styrene or styrenic derivatives via TEMPO (2,2,6,6-tetramethylpiperidenyl-1-oxyl) mediated stable free radical polymerization (SFRP) is described. The unimers are composed of an azobenzene-functionalized core and a TEMPO-modified unit. Homopolymers and copolymers of styrene and acetoxystyrene were synthesized using the mono-and trifunctionalized unimers as initiators under bulk conditions with average molecular weights and polydispersities reported. The studies lay the groundwork for further investigations involving SFRP towards building a light harvesting system by introducing chromophores onto the polymer chains for capturing light and thence transferring it to the azobenzene core.Key words: azo-functionalized unimolecular initiator, stable free radical polymerization, starburst dendrimer.

  描述了合成偶氮苯官能化的多臂单分子引发剂或“unimers”，可以使用苯乙烯或苯乙烯衍生物通过TEMPO（2,2,6,6-四甲基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-氧基-1-
• Molecular balloon, Pd₆L₈ cages: recognition of alkyl sulfate surfactants
  作者：Haeri Lee、Dongwon Kim、Hyejin Oh、Ok-Sang Jung

  DOI：10.1039/c9cc09742b

  日期：——

  The unique molecular balloon system of [Pd6L8](NO3)12 (an inner cavity of 19 × 21 × 25 Å3 ⇄ 13 × 13 × 13 Å3) was carried out via the anion exchange of nitrate with alkyl sulfates.

  通过硝酸盐与烷基硫酸盐的阴离子交换，实现了[Pd6L8]（NO3）12（内腔19×21×25Å3×13×13×13Å3）的独特分子气球系统。