methyl β-apo-10'-carotenoate | 69774-12-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: methyl β-apo-10'-carotenoate
• 英文别名: methyl (2E,4E,6E,8E,10E,12E,14E)-4,9,13-trimethyl-15-(2,6,6-trimethylcyclohex-1-en-1-yl)pentadeca-2,4,6,8,10,12,14-heptaenoate；methyl 10'-β-apo-carotenoate；all-trans-4,9,13-Trimethyl-15-<2',6',6'-trimethylcyclohexen-(1')-yl>-pentadecaheptaen-(2,4,6,8,10,12,14)-oic-(1)-saeuremethylester；4,9,13-Trimethyl-15-<2,6,6-trimethyl-cyclohexen-(1)-yl>-pentadecaheptaen-(2,4,6,8,10,12,14)-saeure-methylester；all-trans-4,9,13-trimethyl-15-(2,6,6-trimethyl-cyclohex-1-enyl)-pentadeca-2,4,6,8,10,12,14-heptaen-1-saeuremethylester；10'-apo-β-caroten-10'-oic acid methyl ester；10'-Apo-β-carotin-10'-saeure-methylester；methyl (2E,4E,6E,8E,10E,12E,14E)-4,9,13-trimethyl-15-(2,6,6-trimethylcyclohexen-1-yl)pentadeca-2,4,6,8,10,12,14-heptaenoate
• CAS: 69774-12-5
• 化学式: C₂₈H₃₈O₂
• 分子量: 406.609
• InChiKey: ABAWJIQACLRTOU-FXOXNNLWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  methyl β-apo-10'-carotenoate 在 chromium(VI) oxide 作用下， 以 苯 为溶剂， 生成 4,9,13,17,17-pentamethyl-16,21-dioxo-docosa-2,4,6,8,10,12,14-heptaenoic acid methyl ester
  参考文献：
  名称：

  Akhtar,M. et al., Journal of the Chemical Society. Perkin transactions I, 1978, p. 1511 - 1524

  摘要：

  DOI：
• 作为产物：
  描述：

  15,15'-didehydro-10'-apo-β-caroten-10'-oic acid methyl ester 在 喹啉 、 Lindlar's catalyst 、 Petroleum ether 作用下， 生成 methyl β-apo-10'-carotenoate
  参考文献：
  名称：

  Testing the requirements of stages of physical activity among adults: The comparative effectiveness of stage-matched, mismatched, standard care, and control interventions

  摘要：

  We tested the comparative efficacy of 4 interventions to increase the physical activity behavior of college personnel randomly assigned to one condition (N = 196, 74% female, M age = 43.4 years) for 16 weeks. Stage-matched and mismatched interventions were developed based on the stages of change from the Transtheoretical Model and were contrasted with standard care (action-oriented) and control interventions to test the requirements of a true stage behavior Repeated measures of multivariate analyses of covariance indicated that the stage-matched and standard care interventions resulted in greater levels of both total and lifestyle physical activity compared with the mismatched and control interventions. The results supported the requirements of a stage behavior as defined by Weinstein, Rothman, and Sutton (1) and the superiority of the stage-matched intervention versus the mismatched intervention. However, the standard care intervention performed as well as the matched intervention, suggesting the need for further investigation. The results are discussed with respect to the high proportion of individuals in the action-oriented stages and previous research findings in the smoking literature.

  DOI：

  10.1207/s15324796abm2403_03

文献信息

• Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases
  作者：Marta Domínguez、Raquel Pequerul、Rosana Alvarez、Joan Giménez-Dejoz、Eszter Birta、Sergio Porté、Ralph Rühl、Xavier Parés、Jaume Farrés、Angel R. de Lera

  DOI：10.1016/j.tet.2018.03.050

  日期：2018.5

  based on the acyclic cross-metathesis of the hexaene derived from retinal and the corresponding partners. These compounds can be enzymatically converted to their carboxylic acids by the human aldehyde dehydrogenases involved in retinaldehyde oxidation. Their kinetic parameters suggest that these enzymes might play a role in the physiological metabolism of apocarotenoids.

  基于己烯的无环交叉复分解，已经实现了三种合成类胡萝卜素的新合成，即14'-apo-β-胡萝卜素，12'-apo-β-胡萝卜素和10'-apo-β-胡萝卜素。来自视网膜和相应的伴侣。这些化合物可以通过参与视黄醛氧化的人醛脱氢酶酶促转化为它们的羧酸。它们的动力学参数表明这些酶可能在类胡萝卜素的生理代谢中起作用。
• Testing the requirements of stages of physical activity among adults: The comparative effectiveness of stage-matched, mismatched, standard care, and control interventions
  作者：Bryan Blissmer、Edward McAuley

  DOI：10.1207/s15324796abm2403_03

  日期：2002.8

  We tested the comparative efficacy of 4 interventions to increase the physical activity behavior of college personnel randomly assigned to one condition (N = 196, 74% female, M age = 43.4 years) for 16 weeks. Stage-matched and mismatched interventions were developed based on the stages of change from the Transtheoretical Model and were contrasted with standard care (action-oriented) and control interventions to test the requirements of a true stage behavior Repeated measures of multivariate analyses of covariance indicated that the stage-matched and standard care interventions resulted in greater levels of both total and lifestyle physical activity compared with the mismatched and control interventions. The results supported the requirements of a stage behavior as defined by Weinstein, Rothman, and Sutton (1) and the superiority of the stage-matched intervention versus the mismatched intervention. However, the standard care intervention performed as well as the matched intervention, suggesting the need for further investigation. The results are discussed with respect to the high proportion of individuals in the action-oriented stages and previous research findings in the smoking literature.
• Akhtar,M. et al., Journal of the Chemical Society. Perkin transactions I, 1978, p. 1511 - 1524
  作者：Akhtar,M. et al.

  DOI：——

  日期：——