2-deoxy-maltotriose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-deoxy-maltotriose
• 英文别名: Glc(a1-4)Glc(a1-4)2-deoxy-D-araHex；(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[(2R,3S,4R)-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₁₈H₃₂O₁₅
• 分子量: 488.443
• InChiKey: IBXAWKBRFWGZTP-CMWXLIRXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.9
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  248
• 氢给体数：
  10
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  2-Deoxy-D-glucose 、 α-环糊精 在 4-alpha-glucanotransferase sodium azide 、 三羟甲基氨基甲烷 、 calcium chloride 作用下， 以 水 为溶剂， 反应 2.5h， 以19%的产率得到2-deoxy-maltose
  参考文献：
  名称：

  Specificity of amylases and cyclodextrin-glucanotransferase in reactions with 2-deoxy-maltooligosaccharides

  摘要：

  2-Deoxy-maltooligosaccharides of different chain length were tested as substrates for exoand endo-amylases. Cleavage occurred with beta-amylase, yielding 2,2'-dideoxy-maltose, and with amyloglucosidase. With the alpha-amylase from Thermomonospora curvata tris-(2-deoxy)-maltotriose and the corresponding tetra- and pentasaccharides were formed. Porcine pancreatic a-amylase did not tolerate the deoxygenated substrate, nor were cyclization experiments with cyclodextrin-glucanotransferase (CGT) successful. In a coupling reaction with CGT, however, a series of transfer products to the acceptor 2-deoxyglucose were obtained. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00040-2

文献信息

• Specificity of amylases and cyclodextrin-glucanotransferase in reactions with 2-deoxy-maltooligosaccharides
  作者：Britta Evers、Miroslav Petříćek、Joachim Thiem

  DOI：10.1016/s0008-6215(97)00040-2

  日期：1997.5

  2-Deoxy-maltooligosaccharides of different chain length were tested as substrates for exoand endo-amylases. Cleavage occurred with beta-amylase, yielding 2,2'-dideoxy-maltose, and with amyloglucosidase. With the alpha-amylase from Thermomonospora curvata tris-(2-deoxy)-maltotriose and the corresponding tetra- and pentasaccharides were formed. Porcine pancreatic a-amylase did not tolerate the deoxygenated substrate, nor were cyclization experiments with cyclodextrin-glucanotransferase (CGT) successful. In a coupling reaction with CGT, however, a series of transfer products to the acceptor 2-deoxyglucose were obtained. (C) 1997 Elsevier Science Ltd.