1,6-己二醇二丙烯酸酯 | 13048-33-4

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 1,6-己二醇二丙烯酸酯
• 中文别名: 1.6-已二醇二丙烯酸酯；1,4-己二醇二丙烯酸酯；二丙烯酸-1,6-己二醇酯；1,6-双(丙烯酰氧基)己烷；二丙烯酸1,6-己二醇酯；HDDA
• 英文名称: 1,6-hexanediol diacrylate
• 英文别名: hexamethylene glycol diacrylate；hexane-1,6-diyl diacrylate；6-prop-2-enoyloxyhexyl prop-2-enoate
• CAS: 13048-33-4
• 化学式: C₁₂H₁₈O₄
• mdl: MFCD00008631
• 分子量: 226.273
• InChiKey: FIHBHSQYSYVZQE-UHFFFAOYSA-N

物化性质

• 熔点：
  6°C
• 沸点：
  295°C
• 密度：
  1.01 g/mL at 25 °C (lit.)
• 蒸气密度：
  >1 (vs air)
• 闪点：
  >230 °F
• 溶解度：
  可溶于氯仿（少许）、DMSO（少许）
• LogP：
  2.81 at 25℃
• 物理描述：
  1,6-hexanediol diacrylate is a clear yellow liquid. (NTP, 1992)
• 蒸汽压力：
  0.017 mm Hg @ 25 °C /Estimated/
• 分解：
  When heated to decomposition it emits acrid smoke and irritating vapors.
• 保留指数：
  1599;1604;1599;1604
• 稳定性/保质期：

  在常温常压下稳定，应避免与氧化物、水分、酸、光和热接触。

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

ADMET

代谢

丙烯酸酯和甲基丙烯酸酯主要通过迈克尔加成反应或谷胱甘肽-S-转移酶与谷胱甘肽结合而解毒。它们还可能通过羧酸酯酶水解。较低分子量的酯类迅速代谢并排出，因此不太可能引起累积毒性。/丙烯酸酯/

Acrylates and methacrylates are detoxified predominantly via conjugation with glutathione via the Michael addition reaction or glutathione-S-transferase. They are also likely to be hydrolyzed via carboxylesterases. The lower molecular weight esters are rapidly metabolized and eliminated, therefore, will not likely cause cumulative toxicity. /Acrylates/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 副作用

皮肤致敏剂 - 一种可以诱导皮肤产生过敏反应的制剂。

Skin Sensitizer - An agent that can induce an allergic reaction in the skin.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

毒理性

• 解毒与急救

基本治疗：建立专利气道。如有必要，进行吸痰。观察呼吸不足的迹象，如有需要，协助通气。通过非循环呼吸面罩以10至15升/分钟的速度给予氧气。监测肺水肿，如有必要进行治疗……。监测休克，如有必要进行治疗……。预见并处理癫痫发作……。对于眼睛污染，立即用水冲洗眼睛。在运输过程中，用生理盐水连续冲洗每只眼睛……。不要使用催吐剂。对于摄入，如果患者能吞咽、有强烈的干呕反射且不流口水，则用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释……。在去污后，用干燥的无菌敷料覆盖皮肤烧伤……。/毒药A和B/

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：对于昏迷、严重肺水肿或呼吸停止的患者，考虑进行口咽或鼻咽插管以控制气道。使用带有气囊面罩的装置进行正压通气技术可能有益。监测心率和必要时治疗心律失常。 ... 开始静脉输液，使用5%葡萄糖盐水/生理盐水： "保持开放"，最低流速/。如果出现低血容量的迹象，使用乳酸钠林格氏液。注意液体过载的迹象。考虑使用药物治疗肺水肿。对于伴有低血容量迹象的低血压，谨慎给予液体。注意液体过载的迹象。使用地西泮（安定）治疗癫痫。使用丙美卡因氢氯化物协助眼部冲洗。 /毒药A和B/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 人类毒性摘录

人类暴露研究/简报/与1,6-己二醇二丙烯酸酯的短暂接触可能会导致迟发性刺激性皮炎。在为期4年对20名工人的观察中，未发生接触致敏。

/HUMAN EXPOSURE STUDIES/ /Brief/ topical contact with 1,6-hexanediol diacrylate may cause delayed irritant dermatitis. During a 4 yr observation of 20 workers, contact sensitization did not occur.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 人类毒性摘录

/体征和症状/ 人类摄入丙烯酸单体后的体征和症状包括崩溃、严重呼吸困难和中枢神经系统刺激。/丙烯酸盐/

/SIGNS AND SYMPTOMS/ Human signs and symptoms following ingestion of acrylic monomers include collapse, severe respiratory difficulties, and CNS stimulation. /Acrylates/

来源:Hazardous Substances Data Bank (HSDB)

安全信息

• TSCA：
  Yes
• 危险等级：
  9
• 危险品标志：
  Xi
• 安全说明：
  S39
• 危险类别码：
  R36/38,R43
• WGK Germany：
  2
• 海关编码：
  2916190090
• 危险品运输编号：
  UN 3082 9/PG 3
• RTECS号：
  AT1430000
• 包装等级：
  III
• 危险类别：
  9
• 危险性防范说明：
  P280,P305+P351+P338
• 危险性描述：
  H315,H317,H319
• 储存条件：
  常温下应密闭避光存放在通风干燥的地方。

SDS

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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : 1,6-Hexanediol diacrylate
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 13048-33-4
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Skin sensitisation (Category 1), H317
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Xi Irritant R36/38
R43
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Warning
Hazard statement(s)
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
Precautionary statement(s)
P280 Wear protective gloves.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard none
Statements
Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

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SECTION 3: Composition/information on ingredients
Substances
Synonyms : HDODA
Formula : C12H18O4
Molecular weight : 226,27 g/mol
CAS-No. : 13048-33-4
EC-No. : 235-921-9
Index-No. : 607-109-00-8
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Hexamethylene diacrylate
CAS-No. 13048-33-4 Skin Irrit. 2; Eye Irrit. 2; Skin <= 100 %
EC-No. 235-921-9 Sens. 1; H315, H317, H319
Index-No. 607-109-00-8
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Hexamethylene diacrylate
CAS-No. 13048-33-4 Xi, R36/38 - R43 <= 100 %
EC-No. 235-921-9
Index-No. 607-109-00-8
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
No data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Light sensitive.
Storage class (TRGS 510): Combustible liquids
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Z677442, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,2 mm
Break through time: 66 min
Material tested:Dermatril® P (KCL 743 / Z677388, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone [phone] test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: liquid
Colour: colourless
b) Odour No data available
c) Odour Threshold No data available
d) pH No data available
e) Melting point/freezing Melting point/freezing point: 5 °C
point
f) Initial boiling point and 107 °C at 0,3 hPa
boiling range
g) Flash point 113 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower No data available
flammability or
explosive limits
k) Vapour pressure < 0,01 hPa at 20 °C
l) Vapour density 7,81 - (Air = 1.0)
m) Relative density 1,01 g/cm3 at 25 °C
n) Water solubility 0,36 g/l at 20 °C - slightly soluble
o) Partition coefficient: n- log Pow: 2,81 at 25 °C
octanol/water
p) Auto-ignition 235 °C at 1.013,25 hPa
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
Other safety information
Relative vapour density 7,81 - (Air = 1.0)

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SECTION 10: Stability and reactivity
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Keep away from direct sunlight.
Incompatible materials
Oxidizing agentsStrong bases, Strong oxidizing agents, Peroxides, Copper, Iron oxides
Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 5.000 mg/kg
LC0 Inhalation - Rat - male and female - 7 h - 0,41 mg/l
LD50 Dermal - Rabbit - 3.650 mg/kg
(OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
Maximisation Test (GPMT) - Guinea pig
Result: May cause sensitisation by skin contact.
(OECD Test Guideline 406)
Germ cell mutagenicity
Mouse
lymphocyte
Result: negative
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose toxicity - Rat - male and female - Oral - No observed adverse effect level - 250 mg/kg
RTECS: AT1430000
burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, To the
best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated.

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SECTION 12: Ecological information
Toxicity
Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - 4,6 - 10 mg/l - 96 h
(DIN 38412)
Toxicity to daphnia and static test EC50 - Daphnia magna (Water flea) - 2,6 mg/l - 48 h
other aquatic
invertebrates
Toxicity to algae static test EC50 - Desmodesmus subspicatus (Scenedesmus subspicatus) - 1,5
mg/l - 72 h
Toxicity to bacteria Respiration inhibition EC50 - Sludge Treatment - ca. 270 mg/l - 30 min
(OECD Test Guideline 209)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 60 - 70 % - Readily biodegradable.
(OECD Test Guideline 310)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available

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SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
No data available
Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

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SECTION 16: Other information
Full text of H-Statements referred to under sections 2 and 3.
Eye Irrit. Eye irritation
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
Skin Irrit. Skin irritation
Skin Sens. Skin sensitisation
Full text of R-phrases referred to under sections 2 and 3
Xi Irritant
R36/38 Irritating to eyes and skin.
R43 May cause sensitisation by skin contact.
Further information
Copyright 2014 Co. LLC. License granted to make unlimited paper copies for internal use
only.
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our knowledge
and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Corporation and its Affiliates shall not be held
liable for any damage resulting from handling or from contact with the above product. See
and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

制备方法与用途

应用 1,6-己二醇二丙烯酸酯可用作有机合成的原料和化工生产的中间体，广泛应用于塑料、粘合剂、纺织品、橡胶、改性共聚物等。

制备 以1,6-己二醇和丙烯酸为原料，强酸性阳离子树脂D072为催化剂，环己烷作为带水剂，对苯二酚作为阻聚剂，经酯化反应合成1,6-己二醇二丙烯酸酯。实验结果表明，在以下条件下效果最佳：(丙烯酸)：(1,6-己二醇)比例为2.2:1，催化剂用量占原料总质量的2.5%，阻聚剂用量按丙烯酸的质量比为0.6%，带水剂用量占原料总质量的70.4%，反应时间4小时，反应温度80～110℃。在这些条件下，成功合成了1,6-己二醇二丙烯酸酯，并且产物收率达93.88%。

<用途> 本品为双官能度功能单体，具有低皮肤刺激、低收缩率和高活性的特点。广泛应用于塑料、粘合剂、纺织品、橡胶、改性共聚物以及注塑件、涂料、油墨、光聚合物和阻焊油墨等。

反应信息

• 作为反应物：
  描述：

  1,6-己二醇二丙烯酸酯 在 disodium hydrogenphosphate 、 双氧水 、 三氟乙酸酐 作用下， 以 二氯甲烷 、 异丙醇 为溶剂， 反应 51.0h， 生成 6-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-hydroxypropanoyl]oxyhexyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-hydroxypropanoate
  参考文献：
  名称：

  Neuromuscular blocking agents. Some approaches to short acting compounds

  摘要：

  A series of amidic and N-methylamidic methyl and trideuteromethyl quaternary analogues of atracurium have been prepared. All were less potent and longer acting neuromuscular blocking agents than atracurium, and all showed appreciable vagal blockade at neuromuscular blocking doses. Replacement of NCH3 by NCD3 failed to affect potency. Fluorosubstitution in the central chain did not reduce duration of action. Attachment of acyloxy substituents to the interquaternary chain of atracurium and related compounds adjacent to their ester groups shortened the duration of action significantly. Diformyloxy substitution was the most effective in reducing duration without adversely affecting other properties apart from potency, which was significantly less than that of atracurium.

  DOI：

  10.1016/0223-5234(92)90180-9
• 作为产物：
  描述：

  6-(3-Bromopropanoyloxy)hexyl 3-bromopropanoate 在 三乙胺 、 对苯二酚 作用下， 以 苯 为溶剂， 生成 1,6-己二醇二丙烯酸酯
  参考文献：
  名称：

  抗肿瘤药。8.O，O′-双（丙烯酰基）-α，ω-链烷二醇的合成和细胞毒性活性。

  摘要：

  DOI：

  10.1002/jps.2600630734
• 作为试剂：
  描述：

  异佛尔酮二异氰酸酯 、 2,5-二叔丁基对苯二酚 、 二月桂酸二丁基锡 、 、 磷 、 、 、 氢氧化钾 、 (E)-3-(thymin-1'-yl)propenal 以 1,6-己二醇二丙烯酸酯 为溶剂， 反应 4.0h， 生成 urethane acrylate
  参考文献：
  名称：

  Phosphorus containing materials, their preparation and use

  摘要：

  描述了一种共聚磷含量聚合物前体，其包括：a）可聚合不饱和键；b）氧羰基或亚氨基羰基团；c）自由羟基或可通过与适当电子亲合剂反应获得的功能基团；以及d）位于碳链末端的含磷氧基团，包括至少一种从羟基磷和可选取代的烃基团通过氧基连接到磷原子的团；其中，聚合物前体：基本上不含卤素物种；分子量（如果是聚合物，则为Mn）为约200至约5,000道尔顿；可选地，在25℃下测得的霍普勒黏度小于约14,000mPa.s。这些聚合物前体可作为可选取代的末端磷酸盐或H-膦酸酯与至少一个邻接烷基烯基羰酰氧基团的化合物之间反应的产物获得。聚合物前体可以与其他单体共聚，以产生诸如含磷聚氨酯等共聚物，例如用作阻燃剂、防腐剂、颜料分散剂和/或粘接剂。

  公开号：

  US20040026671A1

文献信息

• LIQUID CRYSTAL COMPOUND, OPTICAL ELEMENT, POLARIZING PLATE, IMAGE DISPLAY APPARATUS, AND OPTICAL RECORDING MATERIAL
  申请人：Nakanishi Sadahiro

  公开号：US20100076216A1

  公开（公告）日：2010-03-25

  Provided are a liquid crystal compound which can exhibit liquid-crystalline phase even at low temperatures, is excellent in uniform application performance and compatibility with another component, and suppresses inclusion of a polymeric component other than the object component, and an optical element having little defects in appearance, a polarizing plate, an image display apparatus, and an optical recording material using the liquid crystal compound. The liquid crystal compound of the present invention includes two or more chemical structures Q each represented by a general formula (1).

  提供一种液晶化合物，即使在低温下也能表现出液晶相，具有优异的均匀应用性能和与另一组分的兼容性，并抑制除目标组分以外的聚合物组分的包含，并且具有外观上几乎没有缺陷的光学元件，偏光板，图像显示装置和使用该液晶化合物的光学记录材料。本发明的液晶化合物包括由通式（1）表示的两个或更多化学结构Q。
• [EN] COMPOUNDS FOR OPTICALLY ACTIVE DEVICES<br/>[FR] COMPOSÉS POUR DISPOSITIFS OPTIQUEMENT ACTIFS
  申请人：MERCK PATENT GMBH

  公开号：WO2020212543A1

  公开（公告）日：2020-10-22

  The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive unit, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices.

  本发明涉及包含光活性单元的聚合化合物的创新眼科设备，所述聚合化合物，以及特别适合用于组合物和眼科设备的特殊单体化合物。
• COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL
  申请人：Liska Robert

  公开号：US20100303804A1

  公开（公告）日：2010-12-02

  The present invention relates to a polymerization-curable composition for the preparation of biodegradable, biocompatible, cross-linked polymers on the basis of polyvinyl alcohol comprising: 5 to 100% by weight of (a) vinyl ester monomer(s) of one of the general formulas (I) to (III): wherein X is oxygen, sulfur, nitrogen, or phosphorus; n is 1 to 1000, at least 20% of the n being ≧2; the R 1 are selected from hydrogen; straight, branched or cyclic, saturated or unsaturated, n-valent hydrocarbon groups having 1 to 30 carbon atoms, which optionally have heteroatoms and are optionally substituted with one or more substituents selected from —OH, —COON, —CN, —CHO, and ═O, and n-valent radicals of biodegradable, biocompatible oligomers and polymers; m is an integer from 1 to 5; the R 2 are selected from hydrogen, —OH, ═O, and the options listed for R 1 ; and the R 3 are selected from hydrogen, —OH, and the options listed for R 1 ; 0 to 50% by weight of ethylenically unsaturated co-monomers; 0 to 10% by weight of (a) polymerization initiator(s); and 0 to 95% by weight of solvent(s).

  本发明涉及一种用于制备基于聚乙烯醇的可生物降解、生物相容、交联聚合物的聚合固化组合物，包括：按重量计5至100%的(a)乙烯酸酯单体，其具有下列通式(I)至(III)之一： 其中X为氧、硫、氮或磷；n为1至1000，n的至少20%为≧2；R 1 选自氢；直链、支链或环状、饱和或不饱和、含有1至30个碳原子的n价碳氢基团，该基团可选地具有杂原子，并可选地被选自—OH、—COON、—CN、—CHO和═O的一个或多个取代基以及生物降解、生物相容寡聚物和聚合物的n价基团取代；m为1至5的整数；R 2 选自氢、—OH、═O以及R 1 中列出的选项；R 3 选自氢、—OH以及R 1 中列出的选项；按重量计0至50%的乙烯基不饱和共聚单体；按重量计0至10%的(a)聚合引发剂；按重量计0至95%的溶剂。
• ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS
  申请人：Erdogan Belma

  公开号：US20110054115A1

  公开（公告）日：2011-03-03

  A pre-adhesive composition is described comprising an acid-functional (meth)acrylate copolymer and an acylaziridine crosslinking agent, which when crosslinked provides a pressure-sensitive adhesive and pressure-sensitive adhesive articles.

  描述了一种预粘合组合物，包括一个含酸官能基的（甲基）丙烯酸酯共聚物和一个酰基环氮乙烷交联剂，当交联后提供一种压敏粘合剂和压敏粘合剂制品。
• [EN] (METH)ACRYLOYL-AZIRIDINE CROSSLINKING AGENTS AND ADHESIVE POLYMERS<br/>[FR] AGENTS DE RÉTICULATION (MÉTH)ACRYLOYL-AZIRIDINE ET POLYMÈRES ADHÉSIFS
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2011087664A1

  公开（公告）日：2011-07-21

  Described is a pre-adhesive, curable composition comprising an acid-functional (meth)acrylate copolymer and a novel (meth)acryloyl-aziridine crosslinking agent, which when crosslinked provides a pressure-sensitive adhesive composition.

  描述了一种预粘合、可固化的组合物，包括一个含酸官能基的（甲基）丙烯酸酯共聚物和一种新型的（甲基）丙烯酰基-环氮烷交联剂，当交联后形成一种压敏粘合剂组合物。

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