cannabigerol | 25654-32-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: cannabigerol
• 英文别名: 2-[(2Z)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
• CAS: 25654-32-4
• 化学式: C₂₁H₃₂O₂
• 分子量: 316.484
• InChiKey: QXACEHWTBCFNSA-ATVHPVEESA-N

物化性质

• 沸点：
  470.4±40.0 °C(Predicted)
• 密度：
  0.987±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  23
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  橙花醇 、 3,5-二羟基戊苯 在 对甲苯磺酸 作用下， 以 氯仿 为溶剂， 反应 12.0h， 以563 mg的产率得到cannabigerol
  参考文献：
  名称：

  Cannabinerolic acid, a cannabinoid from Cannabis sativa

  摘要：

  Investigation of the leaves of Cannabis sativa resulted in the isolation of a new cannabinoid, cannabinerolic acid. The structure of the new cannabinoid was established on the basis of spectroscopic and chemical evidence.

  DOI：

  10.1016/0031-9422(94)00887-y

文献信息

• POLYCANNABINOIDS, COMPOUNDS, COMPOSITIONS AND METHODS OF USE
  申请人：University of Connecticut

  公开号：US20210322365A1

  公开（公告）日：2021-10-21

  Polymers comprising a plurality of cannabinoids, methods of preparation thereof, and methods of use to treat a number of disease conditions are reported. Also provided are polymer coatings, films, fibers, and non-woven fabrics for a variety of topical applications including stents, bandages, sutures, and transdermal patches.

  本文报告了包含多种大麻素的聚合物，其制备方法以及用于治疗多种疾病状况的方法。同时，还提供了用于各种局部应用的聚合物涂层、膜、纤维和无纺布，包括支架、绷带、缝合线和经皮贴片。
• A composition containing non-psychotropic cannabinoids for the treatment of inflammatory diseases
  申请人：Vivacell Biotechnology Espana S.L.

  公开号：EP2044935A1

  公开（公告）日：2009-04-08

  A composition containing non-psychotropic cannabinoids for the treatment of inflammatory diseases. The invention relates to a composition comprising at least one non-psycotropic cannabinoid and/or at least one phenolic or flavonoid compound and/or Denbinobin and their uses for the prevention and treatment of gastrointestinal inflammatory diseases and for the prevention and treatment of gastrointestinal cancers. It also relates to a phytoextract obtained from the plant Cannabis sativa, more particularly from the selected variety CARMA.

  一种含有非精神类大麻素的组合物，用于治疗炎症性疾病。 本发明涉及一种含有至少一种非精神类大麻素和/或至少一种酚类或黄酮类化合物和/或 Denbinobin 的组合物及其用于预防和治疗胃肠道炎症疾病和预防和治疗胃肠道癌症的用途。它还涉及一种从大麻（Cannabis sativa）植物，特别是从所选品种 CARMA 中提取的植物提取物。
• Pharmaceutical composition and method of manufacturing
  申请人：Speier Gary J.

  公开号：US10238705B2

  公开（公告）日：2019-03-26

  The present invention provides for methods of obtaining an extract of Cannabis plant material as well as subsequent processing of the extract to provide a concentrate of Cannabis. The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of Cannabis, as well as methods of medical treatment that include administering the pharmaceutical dosage forms.

  本发明提供了获得大麻植物材料提取物的方法，以及对提取物进行后续加工以提 供大麻浓缩物的方法。本发明还提供了包括大麻浓缩物（或提取物）的药物剂型（如口服薄膜和透皮贴剂），以及包括施用药物剂型的医疗方法。
• CANNABINOIDCARBONSÄUREN, SALZE VON CANNABINOIDCARBONSÄUREN, DEREN HERSTELLUNG UND ANWENDUNGEN
  申请人：The Health Concept GmbH

  公开号：EP2760444A1

  公开（公告）日：2014-08-06
• COMPOSITION CONTAINING NON-PSYCHOTROPIC CANNABINOIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES
  申请人：Munoz Blanco Eduardo

  公开号：US20100222437A1

  公开（公告）日：2010-09-02

  The invention relates to a composition comprising cannabidiol and Denbinobin and its use in medicine, for example, for the prevention and treatment of gastrointestinal inflammatory diseases and for the prevention and treatment of gastrointestinal cancers.