二氯化二硒 | 10025-68-0

• 物质功能分类: 有机原料
• 分子结构分类: 无机化合物 - 均质非金属化合物 - 其他非金属卤化物
• 中文名称: 二氯化二硒
• 中文别名: 一氯化硒；氯化亚硒(I)；氯化硒
• 英文名称: diselenium dichloride
• 英文别名: Selenium chloride (Se2Cl2)；chloroselanyl selenohypochlorite
• CAS: 10025-68-0
• 化学式: Cl₂Se₂
• 分子量: 228.826
• InChiKey: VIEXQFHKRAHTQS-UHFFFAOYSA-N

物化性质

• 熔点：
  -85°C
• 沸点：
  127°C
• 密度：
  2.73 g/mL at 25 °C(lit.)
• 闪点：
  127°C
• 溶解度：
  reacts with H2O; soluble in CS2, benzene, 2 ctc, chloroform
• 暴露限值：
  ACGIH: TWA 0.2 mg/m3NIOSH: IDLH 1 mg/m3; TWA 0.2 mg/m3
• 稳定性/保质期：
  1. **稳定性**：稳定。 2. **禁配物**：强氧化剂、强酸、强碱、磷、钾、过氧化钾、过氧化钠。 3. **避免接触的条件**：潮湿空气。 4. **聚合危害**：不聚合。

计算性质

• 辛醇/水分配系数(LogP)：
  0.62
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

ADMET

毒理性

• 副作用

神经毒素 - 其他中枢神经系统神经毒素 职业性肝毒素 - 继发性肝毒素：在职业环境中潜在的有毒效应是基于人类摄入或动物实验的中毒案例。 生殖毒素 - 对生殖系统有毒的化学物质，包括后代缺陷以及损伤男性或女性生殖功能。生殖毒性包括发育效应。参见生殖毒性风险评估指南。 皮肤毒素 - 皮肤烧伤。 中毒性肺炎 - 由于吸入金属烟雾或有毒气体和蒸气引起的肺部炎症。

Neurotoxin - Other CNS neurotoxin Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects. See Guidelines for Reproductive Toxicity Risk Assessment. Dermatotoxin - Skin burns. Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

安全信息

• TSCA：
  Yes
• 危险等级：
  8
• 危险品标志：
  T
• 危险类别码：
  R23/24/25
• 危险品运输编号：
  UN 2922 8/PG 2
• WGK Germany：
  3
• RTECS号：
  VS7855000
• 包装等级：
  II
• 危险类别：
  8
• 安全说明：
  S22,S26,S36/37/39,S45
• 储存条件：
  储存注意事项： - 储存在阴凉、通风的库房中。 - 远离火源和热源，库温不超过35℃，相对湿度不超过80%。 - 保持容器密封。 - 应与氧化剂、酸类、碱类及食用化学品分开存放，切忌混储。 - 储区应备有泄漏应急处理设备和合适的收容材料。

SDS

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Section 1: Product Identification
Chemical Name: Selenium (I) chloride (99%-Se)
CAS Registry Number: 10025-68-0
Formula: Se2Cl2
EINECS Number: none
Chemical Family: metal halide
Synonym: none

---

Section 2: Composition and Information on Ingredients
Ingredient CAS Number Percent ACGIH (TWA) OSHA (PEL)
Title Compound 10025-68-0 100% 0.2mg/m3 (as Se) 0.2mg/m3 (as Se)

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Section 3: Hazards Identification
Emergency Overview: Harmful by inhalation, in contact with skin and if swallowed. Corrosive to skin and eyes.
Primary Routes of Exposure: Ingestion, inhalation, skin, eyes
Eye Contact: Causes burns to the eyes.
Skin Contact: Causes burns to the skin.
Inhalation: Harmful by inhalation. Inhalation of vapors will lead to burning of the respiratory tract.
Ingestion: Harmful if swallowed. Caustic burns to the gastrointestinal system may occur.
Harmful by inhalation, in contact with skin and if swallowed. Corrosive to skin, eyes and respiratory tract and
Acute Health Affects:
cause eye, skin burns, dyspnea (breathing difficulty), and pulmonary edema
Chronic Health Affects: No information available on long-term chronic effects.
NTP: No
IARC: No
OSHA: No

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SECTION 4: First Aid Measures
Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
Eye Exposure:
assistance in keeping their eye lids open. Get immediate medical attention.
Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
Skin Exposure:
irritation persists.
Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
Inhalation:
in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
Ingestion:
vomiting only if directed by medical personnel.

---

SECTION 5: Fire Fighting Measures
Flash Point: not applicable
Autoignition Temperature: none
Explosion Limits: none
Extinguishing Medium: Carbon dioxide, sand, dry chemical powder.
If involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained
Special Fire Fighting Procedures:
breathing apparatus and full protective clothing.
Hazardous Combustion and If involved in a fire this material may emit toxic chlorine and hydrochloric acid fumes.
Decomposion Products:
Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards.

---

SECTION 6: Accidental Release Measures
Small spills can be neutralized with powdered sodium bicarbonate, lime, or calcium carbonate and swept up.
Spill and Leak Procedures: Large spills in areas not adequately ventilated will require an evacuation of site. Emergency response teams
will require self-contained breathing apparatus.

---

SECTION 7: Handling and Storage
Store material in a tightly sealed bottle away from moisture. If possible, handle material in an efficient fume
Handling and Storage:
hood. Prolonged exposure to the atmosphere may lead to degradation of the product.

---

SECTION 8: Exposure Controls and Personal Protection
Eye Protection: Always wear approved safety glasses when handling a chemical substance in the laboratory.
Skin Protection: Wear protective clothing and gloves. Consult with glove manufacturer to determine the proper type of glove.
Ventilation: If possible, handle the material in an efficient fume hood.
If in form of fine dust and ventilation is not available a respirator should be worn. The use of respirators
Respirator:
requires a Respirator Protection Program to be in compliance with 29 CFR 1910.134.
Ventilation: If possible, handle the material in an efficient fume hood.
Additional Protection: No additional protection required.

---

SECTION 9: Physical and Chemical Properties
Color and Form: red liq.
Molecular Weight: 228.53
Melting Point: -85°
Boiling Point: 130°C dec.
Vapor Pressure: no data
Specific Gravity: 2.77
Odor: Pungent odor.
Solubility in Water: reacts with water

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SECTION 10: Stability and Reactivity
Stability: moisture sensitive
Hazardous Polymerization: no hazardous polymerization
Conditions to Avoid: contact with moisture
Incompatibility: water, mineral acids and active metals
Decomposition Products: with moisture: hydrochloric acid and selenium oxide.

---

SECTION 11: Toxicological Information
RTECS Data: No information available in the RTECS files.
Carcinogenic Effects: no data
Mutagenic Effects: no data
Tetratogenic Effects: no data

---

SECTION 12: Ecological Information
Avoid release to groundwater or waterways. Very toxic to aquatic organisms. May cause long-term adverse
Ecological Information:
effects.

---

SECTION 13: Disposal Considerations
Disposal: Dispose of according to local, state and federal regulations.

---

SECTION 14: Transportation
Shipping Name (CFR): Corrosive liquids, Toxic, N.O.S.
Hazard Class (CFR): 8
Additional Hazard Class (CFR): 6.1
Packaging Group (CFR): II
UN ID Number (CFR): UN# 2922
Shipping Name (IATA): Corrosive liquid, Toxic, N.O.S.
Hazard Class (IATA): 8
Additional Hazard Class (IATA): 6.1
Packaging Group (IATA): II
UN ID Number (IATA): UN# 2922

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SECTION 15: Regulatory Information
TSCA: Listed in the TSCA inventory.
SARA (Title 313): Title compound: See category code N725 for reporting
Second Ingredient: none

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

用途

用于电子、仪表等工业的生产。

生产方法

1. 反应装置：带滴液漏斗的圆底烧瓶。将115g新升华的硒酰氧化物（SeO₂）放入烧瓶中，加入500mL浓度为36%～37%的浓盐酸使其溶解，再加入235g硒。然后从滴液漏斗中逐滴滴入浓硫酸，直到不再产生HCl气体为止。反应生成的红色硒二氯化物（Se₂Cl₂）会沉在反应器底部，冷却后使用分液漏斗将其分离出来。用浓硫酸洗涤数次，或溶于发烟硫酸中，通入HCl析出产物。产品中残留的硫酸可通过无水BaCl₂处理，在隔绝湿气条件下通过玻璃砂芯漏斗过滤。收率可达90%左右。

2. 反应装置：带气体导入管的蒸馏烧瓶，导入管插至瓶底，烧瓶上接一个下降冷凝管并与接受瓶相连，从接受瓶引出一气体导出管，经装有酸的洗涤瓶后通到通风橱的排气管中。将300g发烟硫酸（含30%SO₃）加入蒸馏瓶中，在摇动下加入100g粉末状硒。干燥的HCl气体通入反应混合物，并小心加热蒸馏瓶，使硒刚刚开始挥发。不久接受瓶中开始有Se₂Cl₂滴下。调节蒸馏速度，在2小时内约馏出130g产物。粗产品可用少量发烟硫酸与之混合摇荡数次至不再呈绿色为止。最后按制法1处理。

类别

有毒物品

毒性分级

剧毒

可燃性危险特性

不燃；遇水、酸释放剧毒硒化氢气体

储运特性

库房通风低温干燥，与酸类及食品分开储运

灭火剂

二氧化碳、干粉、砂土

反应信息

• 作为反应物：
  描述：

  二氯化二硒 在 trimethylsilyl azide 作用下， 以 二氯甲烷 为溶剂， 以70%的产率得到
  参考文献：
  名称：

  Siivari, Jari; Chivers, Tristram; Laitinen, Risto S., Inorganic Chemistry, 1993, vol. 32, # 20, p. 4391 - 4395

  摘要：

  DOI：
• 作为产物：
  描述：

  selenium sulfur trioxide 在 盐酸 作用下， 以 硫酸 为溶剂， 生成 二氯化二硒
  参考文献：
  名称：

  Divers, E.; Shimose, M., Journal of the Chemical Society, 1884, vol. 45, p. 195 - 195

  摘要：

  DOI：
• 作为试剂：
  描述：

  、 苯硒酚 在 二氯化二硒 、 sodium hydroxide 、 copper dichloride 作用下， 以 二甲基亚砜 为溶剂， 反应 12.0h， 以92%的产率得到5,11-Diselena-benzo[a]fluorene-6-selone
  参考文献：
  名称：

  一种制备珍珠优化剂二硒代香豆素并苯并硒吩类化合物的方法

  摘要：

  本发明公开了一种制备式(Ⅳ)所示的珍珠优化剂二硒代香豆素并苯并硒吩类化合物的方法，制备方法为：式(Ⅰ)所示的2‑硒酚基肉桂醛类化合物、式(Ⅱ)所示的二氯化二硒和式(Ⅲ)所示的苯硒酚类化合物，以氯化铜为催化剂，以氢氧化钠为促进剂，以二甲基亚砜为介质，制得反应产物，所述的反应产物通过后处理制得珍珠优化剂二硒代香豆素并苯并硒吩类化合物。该发明具有工艺简单、成本低廉、产物具有安全和良好生理活性等优点。在相关的珍珠优化剂合成工业领域具有重要前景。

  公开号：

  CN113004308A

文献信息

• Preparation and characterisation of [Pt(SeSN2)(PR3)2], [Pt(Se2N2)(PR3)2], [Pt(SeSN2H)(PR3)2]BF4, and [Pt(Se2N2H)(PR3)2]BF4
  作者：Ivan P. Parkin、J. Derek Woollins

  DOI：10.1039/dt9900000925

  日期：——

  tetrahydrofuran–benzene produces [Pt(SeSN2H)(PR3)2] BF4 or [Pt(Se2N2H)(PR3)2] BF4 quantitatively according to 31P n.m.r. spectroscopy (ca. 75% isolated). The identity of the complexes was established by 31P n.m.r., i.r., mass spectra, and microanalyses. Proton-exchange reactions reveal increasing basicity in the series [Pt(S2N2)(PR3)2]≈[Pt(SeSN2)(PR3)2], [Pd(S2N2)(PR3)2], [Pt(Se2N2)(PR3)2].

  [Se 2 N 2 S] 2 Cl 2或SeCl 4- [S 4 N 3 ] Cl与[PtCl 2（PR 3）2 ]（PR 3 = PEt 3，PMe 2 Ph，PMePh 2，PPh的反应3，或在液态氨中的1/2 Ph 2 PCH 2 CH 2 PPh 2）得到[Pt（SeSN 2）（PR 3）2 ]类型的络合物（产率约70％）。SeCl 4的反应与[PtCl 2（PR 3）2 ]（PR 3 = PEt 3，PMe 2 Ph，PMePh 2，PPh 3或½Ph 2 PCH 2 CH 2 PPh 2）在液氨中产生[Pt（Se 2 N 2） （PR 3）2 ]的可变收率（约24–74％）。用HBF处理[Pt（SeSN 2）（PR 3）2 ]或[Pt（Se 2 N 2）（PR 3）2 ]根据31 P nmr光谱法（约75），四氢呋喃-苯中的4产生定量的[Pt（SeSN 2 H）（PR 3） 2
• Icosahedral <i>m</i>-Carboranes Containing Exopolyhedral B–Se and B–Te Bonds
  作者：Harrison A. Mills、Fadi Alsarhan、Ta-Chung Ong、Milan Gembicky、Arnold L. Rheingold、Alexander M. Spokoyny

  DOI：10.1021/acs.inorgchem.1c02981

  日期：2021.12.20

  B(9)–Se and B(9)–Te σ bonds despite the electron-donating ability of the B(9) vertex. While these molecules are known, little has been done to thoroughly evaluate their electrophilic and nucleophilic behavior. Herein, we report an assessment of the electrophilic reactivity of m-carboranylselenyl(II), -tellurenyl(II), and -tellurenyl(IV) chlorides and establish their reactivity pattern with Grignard

  尽管 B(9) 顶点具有供电子能力，但含硫属碳硼烷已为人所知数十年，并具有稳定的外多面体 B(9)-Se 和 B(9)-Te σ 键。虽然这些分子是已知的，但很少有人彻底评估它们的亲电和亲核行为。在此，我们报告了对间碳硼烷基硒基 (II)、-碲基 (II) 和 - 碲基 (IV) 氯化物的亲电反应性的评估，并建立了它们与格氏试剂、烯烃、炔烃、烯醇化物和富电子的反应模式芳烃。这些亲电反应提供了以前不常见的独特的富电子 B-Y-C (Y = Se, Te) 键合基序。此外，我们表明m -carboranyl selenolate，甚至m-碳硼烷基碲酸盐，可以是亲核试剂并参与亲核芳族取代反应。芳烃取代化学显示通过钯介导的交叉偶联化学进一步扩展到富电子物质。
• Perfluorophenyl derivatives of the elements XV. Perfluoroaromatic derivatives of sulphur, selenium and tellurium
  作者：S.C. Cohen、M.L.N. Reddy、A.G. Massey

  DOI：10.1016/0022-328x(68)80084-1

  日期：——

  The syntheses of several pentafluorophenyl derivatives of sulphur, selenium and tellurium and of four heterocycles containing sulphur and selenium are described.

  描述了硫，硒和碲的几种五氟苯基衍生物的合成以及含有硫和硒的四个杂环的合成。
• Theoretical and Experimental Studies of Six-Membered Selenium−Sulfur Nitrides Se<i>_x</i>S₄_-<i>_x</i>N₂ (<i>x</i> = 0−4). Preparation of S₄N₂ and SeS₃N₂ by the Reaction of Bis[bis(trimethylsilyl)amino]sulfane with Chalcogen Chlorides
  作者：Arto Maaninen、Jari Siivari、Reijo J. Suontamo、Jari Konu、Risto S. Laitinen、Tristram Chivers

  DOI：10.1021/ic9613570

  日期：1997.5.1

  Attempts to prepare selenium-rich species resulted in the formation of elemental selenium or Se(3)N(2)Cl(2). The experimental work was supported by ab initio MO calculations which establish the structural and stability relationships of the different members of the series 1,3-Se(x)()S(4)(-)(x)()N(2) (x = 0-4). Full geometry optimization was carried out for each molecular species using the polarized split-valence

  [（Me（3）Si）（2）N]（2）S与等摩尔量的SCl（2）和S（2）Cl（2）的反应产生S（4）N（2）的收率很高。[（Me（3）Si）（2）N]（2）S与S（2）Cl（2），Se（2）Cl（2）和SeCl（3：1：1）的反应4）产生深棕红色不溶物，根据元素分析，质谱，振动分析和NMR光谱推断其主要为SSeSNSN。尝试准备富含硒的物种导致元素硒或Se（3）N（2）Cl（2）的形成。实验工作得到了从头算MO的支持，该计算确定了1,3-Se（x）（）S（4）（-）（x）（）N（2）系列不同​​成员的结构和稳定性关系。 （x = 0-4）。使用极化分裂价MIDI-4基集对每个分子种类进行了完整的几何优化。考虑了涉及二阶Møler-Plessett微扰理论的电子相关性的影响。发现每个分子都位于为1，3-S（4）N（2）建立的近似半椅构型（即相互作用的平面NEN和EEE片段； E = S，Se
• A simple method for the preparation of selenopheno[3,2-b] and [2,3-b]thiophenes
  作者：Pavel Arsenyan

  DOI：10.1016/j.tetlet.2014.03.024

  日期：2014.4

  A simple strategy for the preparation of novel selenopheno[3,2-b] and [2,3-b]thiophenes by treatment of ethynylthiophenes with selenium(I), (II), and (IV) chlorides and bromides is elaborated.

  阐述了一种通过用氯化硒和氯化硒处理乙炔基噻吩来制备新型硒基[3,2- b ]和[2,3- b ]噻吩的简单策略。