溴化硒(IV) | 7789-65-3

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 其他非金属卤化物
• 中文名称: 溴化硒(IV)
• 中文别名: 四溴化硒；溴硒(IV)
• 英文名称: selenium tetrabromide
• 英文别名: selenium(IV) bromide
• CAS: 7789-65-3
• 化学式: Br₄Se
• 分子量: 398.576
• InChiKey: VTQZBGAODFEJOW-UHFFFAOYSA-N

物化性质

• 熔点：
  70-80 °C (dec.)(lit.)
• 溶解度：
  reacts with H2O; soluble in CS2, chloroform
• 暴露限值：
  ACGIH: TWA 0.2 mg/m3NIOSH: IDLH 1 mg/m3; TWA 0.2 mg/m3
• 稳定性/保质期：

  如果按照规格使用和储存，则不会分解。应避免接触酸以及水分或潮湿环境。该物质具有与Se2Br2相似的不愉快气味，具有吸湿性，在潮湿空气中会分解为溴、Se2Br2和硒。加热时也会发生分解，在水中则会分解为H2SeO3和HBr。它可以溶解于CS2、CHCl3、CCl4中。

计算性质

• 辛醇/水分配系数(LogP)：
  3.0
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• TSCA：
  Yes
• 危险等级：
  8
• 危险类别码：
  R23/24/25,R34,R40
• 危险品运输编号：
  UN 3290 6.1/PG 2
• 包装等级：
  II
• 安全说明：
  S22,S26,S27,S36/37/39,S45
• 储存条件：
  在干性保护气体中处理，保持贮藏容器密封，并将其存放在阴凉、干燥处。

SDS

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Section 1: Product Identification
Chemical Name: Selenium (IV) bromide, 99%
CAS Registry Number: 7789-65-3
Formula: SeBr4
EINECS Number: 232-181-9
Chemical Family: metal halide
Synonym: Selenium tetrabromide

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Section 2: Composition and Information on Ingredients
Ingredient CAS Number Percent ACGIH (TWA) OSHA (PEL)
Title Compound 7789-65-3 100% 0.2mg/m3 (as Se) 0.2mg/m3 (as Se)

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Section 3: Hazards Identification
Material hydrolyzes in contact with moisture releasing corrosive hydrogen bromide fumes. Harmful by
Emergency Overview:
inhalation, in contact with skin and if swallowed.
Primary Routes of Exposure: Ingestion, inhalation, skin, eyes
Eye Contact: Liquid and vapors will cause burns to the eyes. May cause blindness.
Skin Contact: Corrosive to skin. Contact can lead to redness, pain, blistering, ulceration, and scar formation.
Inhalation of choking fumes will result in chemical burns of the respiratory tract, chemical pneumonitis and
Inhalation:
pulmonary edema.
Causes burns to the gastrointestinal system. Selenium compounds may lead to nausea, vomiting, and bloody
Ingestion:
diarrhea.
Material is extremely destructive to all body tissues. Selenium compounds cause nausea, vomiting, bloody
Acute Health Affects:
diarrhea, weakness, chills, headache, and delayed pulmonary edema.
Prolonged exposure to selenium compounds may cause dermatitis, diarrhea, liver damage, nervous disorders,
Chronic Health Affects:
lameness, and loss of vitality.
NTP: No
IARC: No
OSHA: No

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SECTION 4: First Aid Measures
Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
Eye Exposure:
assistance in keeping their eye lids open. Get immediate medical attention.
Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
Skin Exposure:
irritation persists.
Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
Inhalation:
in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
Ingestion:
vomiting only if directed by medical personnel.

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SECTION 5: Fire Fighting Measures
Flash Point: not applicable
Autoignition Temperature: none
Explosion Limits: none
Extinguishing Medium: none required
If involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained
Special Fire Fighting Procedures:
breathing apparatus and full protective clothing.
Hazardous Combustion and If involved in a fire this material may emit corrosive hydrogen bromide fumes.
Decomposion Products:
Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards.

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SECTION 6: Accidental Release Measures
Small spills can be mixed with powdered sodium bicarbonate, lime, or calcium carbonate and swept up.
Spill and Leak Procedures: Spillage in areas not adequately ventilated may require an evacuation of area. Emergency response teams
will require self-contained breathing apparatus.

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SECTION 7: Handling and Storage
Store material in a tightly sealed bottle away from moisture. If possible, handle material in an efficient fume
Handling and Storage:
hood. Exposure to the atmosphere may lead to degradation of the product.

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SECTION 8: Exposure Controls and Personal Protection
Eye Protection: Always wear approved safety glasses when handling a chemical substance in the laboratory.
Skin Protection: Wear protective clothing and gloves. Consult with glove manufacturer to determine proper type of glove.
Ventilation: If possible, handle the material in an efficient fume hood.
In the absence of adequate ventilation a respirator should be worn. The use of a respiratory requires a
Respirator:
Respirator Protection Program to be in compliance with 29 CFR 1910.134.
Ventilation: If possible, handle the material in an efficient fume hood.
Additional Protection: Protective work clothing.

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SECTION 9: Physical and Chemical Properties
Color and Form: reddish black xtl.
Molecular Weight: 398.6
Melting Point: 75° dec.
Boiling Point: no data
Vapor Pressure: no data
Specific Gravity: no data
Odor: Pungent odor.
Solubility in Water: reacts with water

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SECTION 10: Stability and Reactivity
Stability: moisture sensitive
Hazardous Polymerization: no hazardous polymerization
Conditions to Avoid: contact with moisture
Incompatibility: Water, alcohols, strong bases, and active metals.
Decomposition Products: with moisture: hydrogen bromide and hydrobromic acid.

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SECTION 11: Toxicological Information
RTECS Data: No information available in the RTECS files.
Carcinogenic Effects: no data
Mutagenic Effects: no data
Tetratogenic Effects: no data

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SECTION 12: Ecological Information
Ecological Information: No information available

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SECTION 13: Disposal Considerations
Disposal: Dispose of according to local, state and federal regulations.

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SECTION 14: Transportation
Shipping Name (CFR): Toxic solid, Corrosive, Inorganic, N.O.S.
Hazard Class (CFR): 6.1
Additional Hazard Class (CFR): 8
Packaging Group (CFR): II
UN ID Number (CFR): UN# 3290
Shipping Name (IATA): Toxic solid, Corrosive, Inorganic, N.O.S.
Hazard Class (IATA): 6.1
Additional Hazard Class (IATA): 8
Packaging Group (IATA): II
UN ID Number (IATA): UN# 3290

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SECTION 15: Regulatory Information
TSCA: Listed in the TSCA inventory.
SARA (Title 313): Title compound not listed.
Second Ingredient: none

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

类别：腐蚀物品
毒性分级：剧毒
可燃性危险特性：不燃；受热或遇水、酸会释放出剧毒硒化氢等气体
储运特性：应存放在通风低温干燥的库房中，并与酸类及食品分开存放和运输
灭火剂：二氧化碳、干粉、砂土

反应信息

• 作为反应物：
  描述：

  溴化硒(IV) 以 水 为溶剂， 生成 硒脲酸
  参考文献：
  名称：

  Meyer, J.; Wurm, V., Zeitschrift fur anorganische Chemie, 1930, vol. 190, p. 91 - 91

  摘要：

  DOI：
• 作为产物：
  描述：

  selenium 以 not given 为溶剂， 生成 溴化硒(IV)
  参考文献：
  名称：

  Gutbier, A.; Engeroff, F., Kolloid-Zeitschrift, 1914, vol. 15, p. 195 - 195

  摘要：

  DOI：
• 作为试剂：
  描述：

  2-iodoazobenzene 在 正丁基锂 、 溴化硒(IV) 作用下， 以 乙醚 为溶剂， 反应 1.5h， 以24%的产率得到(2-phenylazophenyl-C,N')selenenyl bromide
  参考文献：
  名称：

  Intramolecularly coordinated azobenzene selenium derivatives: Effect of strength of the Se⋯N intramolecular interaction on luminescence

  摘要：

  采用邻-硫化路线合成了一系列 2-苯基偶氮苯基硒衍生物 (6â12)。研究了分子内 Seâ¯N 相互作用的强度对吸收光谱和发射光谱的影响。研究表明，Seâ¯N 二级键作用会产生荧光，但是 Seâ¯N 作用的强度与荧光强度不能直接相关。TD-DFT 计算表明，该化合物吸收光谱中涉及的主要转变是基于配体的 ÏâÏ* 型。

  DOI：

  10.1039/c0dt01319f

文献信息

• Selenopheno[2,3-<i>f</i>]coumarins: novel scaffolds with antimetastatic activity against melanoma and breast cancer
  作者：Pavel Arsenyan、Jelena Vasiljeva、Ilona Domracheva、Iveta Kanepe-Lapsa、Anita Gulbe

  DOI：10.1039/c9nj01682a

  日期：——

  The general aim of the current research is to find novel non-toxic small molecules with antimetastatic activity. Herein we present a series of novel selenopheno[2,3-f]coumarins with low cytotoxicity profiles against cancer cells with different natures (carcinomas, sarcomas, melanomas, neuroblastomas, and hepatomas). Based on their structure–activity relationships (SARs), few compounds selectively induce

  当前研究的总体目的是寻找具有抗转移活性的新型无毒小分子。本文中，我们介绍了一系列新型硒硒香豆素[2,3- f ]香豆素，对不同性质的癌细胞（癌，肉瘤，黑素瘤，神经母细胞瘤和肝癌）具有低细胞毒性。基于它们的结构-活性关系（SAR），很少有化合物选择性地诱导MMP抑制并抑制体内血管生成，最高可达57％（10μM）。某些衍生物是体内极好的药物预防黑色素瘤和乳腺癌转移：高达97％，无视觉副作用。本研究提供了科学证据，表明硒代香豆素香豆素支架是具有转移抑制特性的候选药物开发的有前途的竞争者。
• Thioether coordination to divalent selenium halide acceptors – synthesis, properties and structures
  作者：Andrew Jolleys、William Levason、Gillian Reid

  DOI：10.1039/c2dt32665e

  日期：——

  together with halogenated ligand. The [SeX2(L)2] and [SeX2(L–L)] complexes are all based upon distorted square planar coordination, with two Se-based lone pairs assumed to occupy the (vacant) axial sites, and Se–S bond distances of ca. 2.4–2.6 Å. The 1 : 1 species [SeX2(SMe2)] are T-shaped with trans X groups and weak intermolecular Se⋯X contacts. The SeCl2-thioether complexes are less stable than the

  四价SECL 4和SEBr 4在硫醚配体L的存在（SME减少2，THT）或L-L（MES（CH 2）ñ SME（Ñ = 2或3），直径： -C 6 H ^ 4（SME ）2）在0°C的MeCN溶液中，形成SE（II）硫醚配合物，包括晶体学表征的卤桥链聚合物[SEX 2（SMe 2）]（X = Cl或Br），分子反式-[SEX 2（THT）2 ]，顺式-[SEBr 2 MES（CH 2）2 SMe}]和硫醚桥联的聚合物[SEBr 2 MES（CH 2）3 SMe}]与卤代配体一起作为主要产物。[SEX 2（L）2 ]和[SEX 2（L–L）]络合物均基于扭曲的方形平面配位，假定两个基于SE的孤对占据了（空的）轴向位点，而SE–S键的距离约为 2.4–2.6Å。1：1的物种[SEX 2（SMe 2）]为T形，带有反式X基团，且分子间SE⋯X接触较弱。无论是在CH溶液中，SECl 2-硫醚配合物的稳定性均不如溴化物稳定。2
• Uncharged Selenium Rings as Terminal and Bridging Ligands in Selenium-Rich Iridium Clusters
  作者：Karoline Stolze、Michael Ruck

  DOI：10.1002/zaac.201400092

  日期：2014.7

  Ir8Se40Br10 were obtained by reacting Ir in an excess of Se and SeBr4 at 300 °C for two weeks. The monoclinic crystal structure [space group P21/c, a = 1371.9(1) pm, b = 1108.1(1) pm, c = 2058.2(1) pm, β = 106.897(2)° at 296(1) K] consists of uncharged clusters Ir8Se40Br10 = (Ir3+)8(Se22–)(Se42–)6(Se7)2(Br–)10. The iridium(III) cations are coordinated octahedrally by selenium and bromide ions. While the oligoselenide

  通过将 Ir 在过量的 Se 和 SeBr4 中在 300 °C 下反应两周，获得 Ir8Se40Br10 的紫色空气稳定晶体。单斜晶体结构 [空间群 P21/c, a = 1371.9(1) pm, b = 1108.1(1) pm, c = 2058.2(1) pm, β = 106.897(2)° at 296(1) K]不带电荷的团簇 Ir8Se40Br10 = (Ir3+)8(Se22–)(Se42–)6(Se7)2(Br–)10。铱 (III) 阳离子与硒和溴离子八面体配位。虽然低聚硒阴离子提供了高簇内连接性，在 Se22– 的情况下为 μ6-η2，而在 Se42– 的情况下为 μ4-η3，但末端不带电的 Se7 环具有船构象并且是 η1 配位。大约 10% 的 Se7 环被具有椅子构象的 Se6 环取代。使用 SeCl4 的类似反应产生了 Ir2Se9Cl6 的朱红色空气稳定晶体。单晶上的
• Synthesis and structure of arylselenium(<scp>ii</scp>) and aryltellurium(<scp>ii</scp>) cations based on rigid 5-<i>tert</i>-butyl-1,3-bis-(<i>N</i>-pentylbenzimidazol-2′-yl)benzenes
  作者：Varsha Rani、Manjusha Boda、Saravanan Raju、G. Naresh Patwari、Harkesh B. Singh、Ray J. Butcher

  DOI：10.1039/c8dt01148f

  日期：——

  stable arylselenium(II) complexes: [Pentyl(N^C^N)Se+]2[HgCl4]2− (20) and [Pentyl(N^C^N)Se+]2[HgBr4]2− (21). This is the first report on the formation of NCN pincer-based arylselenium(II) cations via the transmetalation route. Similar reactions were further investigated with several tellurium precursors: TeCl4, TeBr4 and TeI2} which resulted in the formation of analogous aryltellurium(II) complexes: [P

  尝试使用汞前驱物[ Pentyl（N ^ C ^ N）HgCl]（19）与卤化硒（SeCl 4，SeBr 4和SeCl 2）进行金属转移反应，以获得相应的有机三氯化硒[ Pentyl（N ^ C ^ N）SeCl 3 ]，三溴化物[ Pentyl（N ^ C ^ N）SeCl 3 ]和一氯化物[ Pentyl（N ^ C ^ N）SeCl]分别为[（N ^ C ^ N）= 5-叔-丁基-1，3-双-（N-戊基-苯并咪唑-2'-基）苯基]。但是，在所有情况下，都观察到硒卤素键非常容易电离，从而导致分离出一类新的空气稳定的芳基硒（II）络合物：[戊基（N ^ C ^ N）Se + ] 2 [HgCl 4 ] 2-（20）和[戊基（N ^ C ^ N）Se + ] 2 [HgBr 4 ] 2-（21）。这是关于通过过渡金属化途径形成基于NCN钳子的芳基硒（II）阳离子的第一份报告。用几种碲前体TeCl
• Selenium-Rich Octanuclear Iridium Clusters with Mixed-Valent Selenium Ligands in the Densest Known Packing of Ellipsoids
  作者：Karoline Stolze、Anja Günther、Herbert C. Hoffmann、Michael Ruck

  DOI：10.1002/zaac.201300581

  日期：2014.4

  in the SeBr2 units. The iridium(III) cations are coordinated octahedrally by selenium atoms and bromide ions. The octahedra share common vertices, while the oligoselenide anions provide high intra-cluster connectivity: μ6-η2 in the case of Se22– and μ4-η3 for Se42–. In parts the cluster resembles a cut-out of the rhombohedral Ir3Se8 framework structure. The ellipsoidal clusters form an excellent approximation

  Ir8Se28Br14·2H2O 的暗红色空气稳定晶体是通过将铱在过量的硒和四溴化硒中在 300°C 下反应 1 周获得的。晶体结构为单斜晶系（空间群 P21/n），a = 1274.66(3) pm, b = 1211.48(3) pm, c = 1743.82(4) pm, β = 91.227(1)° at 296(1) K. 该结构由不带电的团簇 Ir8Se28Br14 = (Ir3+)8(Se22–)(Se42–)6(SeBr2)2(Br–)10 组成，每个团簇有两个水分子。硒采用三种不同的氧化态，二硒化哑铃中的-I，四硒化链中的-I和±0，以及SeBr2单元中的+II。铱 (III) 阳离子通过硒原子和溴离子八面体配位。八面体共享公共顶点，而低聚硒化物阴离子提供高簇内连接性：Se22– 的情况下为 μ6-η2，Se42– 的情况下为 μ4-η3。在某些方面，该簇类似于菱形 Ir3Se8