α-gentiobiose | 5995-99-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-gentiobiose
• 英文别名: β-gentiobiose；gentiobiose；Epigentiobiose；Gentiobiose, alpha-；(2S,3R,4S,5S,6R)-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol
• CAS: 5995-99-3
• 化学式: C₁₂H₂₂O₁₁
• 分子量: 342.3
• InChiKey: DLRVVLDZNNYCBX-LFWCVFAXSA-N

物化性质

• 沸点：
  662.8±55.0 °C(Predicted)
• 密度：
  1.76±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  α-gentiobiose 在 β-D-glucosidase (sweet almonds) sodium trideuterioacetate 作用下， 以 重水 为溶剂， 反应 1.0h， 生成 D-葡萄糖
  参考文献：
  名称：

  1H-NMR-不饱和酮和β-d-葡萄糖苷双糖。II

  摘要：

  摘要1H NMR光谱法用于测定六种具有D-葡萄糖单元的二糖的酶促水解速率，所述二糖为纤维二糖，拉米纳糖，龙胆二糖，麦芽糖，黑糖和异麦芽糖。用甜杏仁中的β-d-葡糖苷酶水解三种β-d-葡糖苷键联的二糖，并将三种α-d-葡糖苷键合二糖用面包酵母中的麦芽糖酶水解。结果表明，水解速率在很大程度上取决于OH-1的位置。动力学研究直接得出了在低底物浓度下两种端基异构体酶促水解的一级速度常数的商（底物浓

  DOI：

  10.1016/0008-6215(92)80094-h
• 作为产物：
  描述：

  2,3,4-tri-O-benzyl-D-glucopyranose 在 钯 potassium tert-butylate 、 氢气 作用下， 生成 α-gentiobiose
  参考文献：
  名称：

  通过1-0-烷基化合成α-和β-吡喃葡萄糖苷

  摘要：

  部分保护的吡喃葡萄糖1和半乳糖吡喃糖13的1-0烷基化导致β-糖苷和β-二糖4a-d和14的便捷，短期合成。在0-6带有较大保护基的葡糖醛糖2仅产生α。 -异头物（异麦芽糖苷衍生物）5。

  DOI：

  10.1016/0040-4039(80)80236-x

文献信息

• Process for producing aglycon and flavor-improved food containing the aglycon by diglycosidase, and converting agent to be used in the process
  申请人：Tsuruhami Kazutaka

  公开号：US20060216281A1

  公开（公告）日：2006-09-28

  A physiologically active substance of aglycon type, in particular, aglycon isoflavone, can be efficiently produced, without resort to any acid/alkali treatment or fermentation and substantially without changing the physical properties of a material, by treating the material with a sufficient amount of diglycosidase for a sufficient period of time at an appropriate temperature and pH so that a physiologically active substance of glycoside type contained in the material can be converted into the physiologically active substance of aglycon type. Moreover, by using diglycosidase and/or a specific enzyme preparation, the aglycon content in a protein or protein-containing food can be increased and the flavor thereof can be improved.

  一种生理活性物质，特别是糖苷型异黄酮的活性物质，可以通过使用足够量的二糖苷酶在适当的温度和pH下足够长的时间处理原料，而无需采用任何酸碱处理或发酵，并且基本上不改变材料的物理性质，从而高效产生。这样，原料中含有的糖苷型生理活性物质可以转化为糖苷型生理活性物质。此外，通过使用二糖苷酶和/或特定酶制剂，可以增加蛋白质或含蛋白质食品中的糖苷型物质含量，并改善其风味。
• NOVEL LACTIC ACID BACTERIUM AND METHOD FOR PRODUCING L-LACTIC ACID USING SAME
  申请人：Sonomoto Kenji

  公开号：US20130171705A1

  公开（公告）日：2013-07-04

  L-Lactic acid fermentation using non-edible biomass requires a lactic acid bacterium suitable for fermentation using a mixture comprising oligosaccharides or mixed saccharides produced by enzymatic treatment of cellulose and hemicellulose, so that simultaneous saccharification and fermentation are enabled. Further, it must be taken into consideration that use of pentoses such as xylose derived form non-edible biomass as the raw material provides lactic acid as well as equimolar acetic acid, which halves the molar yield of lactic acid, and high concentration L-lactic acid induces fermentation inhibition, which makes it difficult to produce L-lactic acid at high yield. The present invention provides a novel lactic acid bacterium that can solve these problems. With the lactic acid bacterium of the present invention, L-lactic acid showing a high optical purity of 99.9% or higher can be efficiently produced by using a mixture of glucose and cellobiose as a raw material without substrate inhibition and substantially without generation of by-products. The method of the present invention is applicable to efficient production of L-lactic acid from a non-edible biomass raw material.

  利用非食用生物质进行L-乳酸发酵需要一种适合使用混合寡糖或混合糖（由纤维素和半纤维素经酶处理产生）进行发酵的乳酸菌，从而实现同时糖化和发酵。此外，必须考虑使用来自非食用生物质的木糖等戊糖作为原料会产生乳酸和等摩尔的乙酸，从而减半乳酸的摩尔产量，高浓度的L-乳酸会引起发酵抑制，使高产L-乳酸变得困难。本发明提供了一种新的乳酸菌，可以解决这些问题。使用本发明的乳酸菌，可以高效地利用葡萄糖和纤维二糖混合物作为原料，无底物抑制且几乎不产生副产物地生产出光学纯度高达99.9％或更高的L-乳酸。本发明的方法适用于从非食用生物质原料中高效生产L-乳酸。
• METHOD FOR PRODUCING L-LACTIC ACID BY LACTIC ACID BACTERIUM UNDER PRESENCE OF PENTOSE AND CELLOOLIGOSACCHARIDES
  申请人：Sonomoto Kenji

  公开号：US20130203134A1

  公开（公告）日：2013-08-08

  The present invention thus provides a method for producing L-lactic acid, which comprises the step of culturing a lactic acid bacterium that can produce L-lactic acid in a medium containing any one selected from the group consisting of cellobiose, cellooligosaccharides, xylose, arabinose, and glucose derived from cellulose and/or hemicellulose as a substrate to obtain L-lactic acid. In a preferred embodiment of the present invention, Enterococcus mundtii NITE BP-965 can be used.

  本发明提供了一种生产L-乳酸的方法，包括在含有来自纤维素和/或半纤维素的葡萄糖、纤维二糖、纤维寡糖、木糖、阿拉伯糖中的任何一种作为底物的培养基中培养能够产生L-乳酸的乳酸菌的步骤，以获得L-乳酸。在本发明的一个首选实施例中，可以使用Enterococcus mundtii NITE BP-965。
• Synthetic Archaeal Glycolipid Adjuvants
  申请人：Sprott Dennis

  公开号：US20100316657A1

  公开（公告）日：2010-12-16

  Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are obtained from appropriate Archaea. Archaeosome lipid vesicles are formulated from the synthetic lipids selected to serve as antigen carriers that target antigen-presenting cells and promote an appropriate immune response to the antigen.

  考古单细胞生物脂质佐剂是通过将各种碳水化合物或阴离子极性基团化学偶联到考古单细胞生物脂质核的自由羟基上合成的。通过适当的考古单细胞生物获得化学稳定的脂质核，如饱和的考古单细胞生物脂和卡尔德考古单细胞生物脂。从选定的合成脂质制备考古体脂质小泡，作为抗原载体，靶向抗原呈递细胞并促进适当的免疫应答。
• PROCESS FOR PRODUCING AGLYCON BY USING DIGLYCOSIDASE AND FLAVOR-IMPROVED FOOD CONTAINING THE AGLYCON AND CONVERTING AGENT TO BE USED IN THE PROCESS
  申请人：Amano Enzyme Inc.

  公开号：EP1270735A1

  公开（公告）日：2003-01-02

  A physiologically active substance of aglycon type, in particular, aglycon isoflavone, can be efficiently produced, without resort to any acid/alkali treatment or fermentation and substantially without changing the physical properties of a material, by treating the material with a sufficient amount of diglycosidase for a sufficient period of time at an appropriate temperature and pH so that a physiologically active substance of glycoside type contained in the material can be converted into the physiologically active substance of aglycon type. Moreover, by using diglycosidase and/or a specific enzyme preparation, the aglycon content in a protein or protein-containing food can be increased and the flavor thereof can be improved.

  在适当的温度和 pH 值下，用足量的双糖苷酶对材料进行足够时间的处理，使材料中含有的苷类生理活性物质转化为苷类生理活性物质，就可以有效地生产苷元类生理活性物质，特别是苷元异黄酮，而无需进行任何酸碱处理或发酵，也基本上不会改变材料的物理性质。此外，通过使用二糖苷酶和/或特定酶制剂，可以增加蛋白质或含蛋白质食品中的苷元含量，并改善其风味。