申请人:REGENTS OF THE UNIVERSITY OF MINNESOTA
公开号:US20220154156A1
公开(公告)日:2022-05-19
Provided herein are lactonases. In one embodiment, the lactonases are metallo-β-lactamase-like lactonase (MLL) enzymes having altered characteristics such as altered catalytic activity and/or altered substrate specificity. Also provided are genetically modified microbes able to express a MLL enzyme, compositions that include a MLL enzyme, and methods of using a MLL enzyme.