luteolin-4'-O-glucoside | 6920-38-3

• 物质功能分类: 生物化工 - 提取物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: luteolin-4'-O-glucoside
• 英文别名: luteolin 4'-glucoside；luteolin 4′-O-glucoside；Luteolin-4'-glucoside；5,7-dihydroxy-2-[3-hydroxy-4-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
• CAS: 6920-38-3
• 化学式: C₂₁H₂₀O₁₁
• mdl: MFCD00017468
• 分子量: 448.383
• InChiKey: UHNXUSWGOJMEFO-MKJMBMEGSA-N

物化性质

• 熔点：
  210°C (dec.)
• 沸点：
  814.5±65.0 °C(Predicted)
• 密度：
  1.713±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  186
• 氢给体数：
  7
• 氢受体数：
  11

文献信息

• Tire with rubber containing flavone
  申请人：THE GOODYEAR TIRE & RUBBER COMPANY

  公开号：EP1391327A1

  公开（公告）日：2004-02-25

  The invention relates to a rubber composition and a pneumatic tire having a component comprising a rubber containing the reaction product of a flavone and a methylene donor.

  本发明涉及一种橡胶组合物和充气轮胎，其成分包括含有黄酮和亚甲基供体反应产物的橡胶。
• Process for producing concentrated and refined actives from tissues and byproducts of Olea europaea with membrane technologies
  申请人：Phenofarm S.r.l.

  公开号：EP2338500A1

  公开（公告）日：2011-06-29

  The invention concerns an integrated process affording the production of purified fractions, as powder or concentrated solution, consisting of different biologically active compounds and families of compounds, starting from olive tree tissues and wastes of the olive oil industry and olive tree cultures, in particular olive tree leaves and twigs (pruning wastes), residues from the oil production (pomace or husks) and pigmented olive pulp. The refined products obtainable comprise not only oleuropein, hydroxytyrosol and related compounds, but also verbascoside and red anthocyanoside pigments. The proposed process is based on the integration of hot or cold extraction from the various vegetal starting materials with separation techniques by membrane tangential filtration, specifically microfiltration (MF) or ultrafiltration (UF), optionally followed by nanofiltration (NF) and completed by reverse osmosis (Ol). These operations are completed, where necessary, by refining treatments of the thus obtained fractions of UF retentate, NF retentate and Ol retentate on chromatographic resins.

  本发明涉及一种综合工艺，该工艺可生产粉末状或浓缩溶液状的纯化馏分，这些馏分由不同的生物活性化合物和化合物家族组成，原料来自橄榄树组织以及橄榄油工业和橄榄树栽培过程中产生的废弃物，特别是橄榄树叶和树枝（修剪废弃物）、橄榄油生产过程中产生的残渣（果渣或果壳）以及带色素的橄榄果肉。可获得的精制产品不仅包括油菜素、羟基酪醇和相关化合物，还包括马鞭草苷和红色花色苷色素。 拟议工艺的基础是从各种植物起始材料中进行热提取或冷提取，并采用切向膜过滤分离技术，特别是微滤（MF）或超滤（UF），之后可选择纳滤（NF），最后采用反渗透（OL）。必要时，对由此获得的 UF 回流液、NF 回流液和 Ol 回流液馏分在色谱树脂上进行精制处理，以完成这些操作。
• Use of an edelweiss extract
  申请人：DSM IP Assets B.V.

  公开号：EP2623094A1

  公开（公告）日：2013-08-07

  The present invention relates to a novel topical use of an edelweiss extract as a skin active agent for protection, strengthening, improvement and/or regeneration of skin barrier function as well as for prevention against skin barrier damages.

  本发明涉及一种新颖的酢浆草提取物外用皮肤活性剂，用于保护、增强、改善和/或再生皮肤屏障功能以及预防皮肤屏障损伤。
• Rubber composition and tire with rubber containing flavone
  申请人：The Goodyear Tire & Rubber Company

  公开号：EP2730431A1

  公开（公告）日：2014-05-14

  A rubber composition comprising a diene based elastomer and an adhesion promoter derived from a flavone, a methylene donor and a methylene acceptor is disclosed. The rubber composition is essentially free of cobalt. Also, a pneumatic tire comprising such a rubber composition is disclosed.

  本发明公开了一种橡胶组合物，该组合物包含一种二烯基弹性体和一种由黄酮、亚甲基供体和亚甲基受体衍生的附着力促进剂。该橡胶组合物基本上不含钴。此外，还公开了一种包含这种橡胶组合物的充气轮胎。
• NOVEL GLYCOSYLTRANSFERASE GENE AND USE THEREOF
  申请人：Suntory Holdings Limited

  公开号：EP2818547A1

  公开（公告）日：2014-12-31

  A polynucleotide is provided that encodes a protein having activity that transfers a sugar to the hydroxyl group at the 4'-position of a flavone. The polynucleotide is selected from the group consisting of: (a) a polynucleotide composed of the base sequence of SEQ ID NO: 1; (b) a polynucleotide that hybridizes under stringent conditions with a polynucleotide composed of a base sequence complementary to the base sequence of SEQ ID NO: 1, and encodes a protein having activity that transfers a sugar to the hydroxyl group at the 4'-position of a flavone; (c) a polynucleotide encoding a protein composed of the amino acid sequence of SEQ ID NO: 2; and, (d) a polynucleotide encoding a protein composed of an amino acid sequence in which one or a plurality of amino acids have been deleted, substituted, inserted and/or added in the amino acid sequence of SEQ ID NO: 2, and having activity that transfers a sugar to the hydroxyl group at the 4'-position of a flavone.

  提供了一种多核苷酸，它编码的蛋白质具有将糖转移到黄酮 4'-位羟基上的活性。该多核苷酸选自由下列组成的一组：(a) 由 SEQ ID NO: 1 的碱基序列组成的多核苷酸；(b) 在严格条件下与由与 SEQ ID NO：1 的碱基序列互补的多核苷酸杂交的多核苷酸，该多核苷酸编码具有将糖转移到黄酮 4'-位羟基的活性的蛋白质；(c)编码由 SEQ ID NO：2 的氨基酸序列组成的蛋白质的多核苷酸，该蛋白质具有将糖转移到黄酮 4'-位羟基上的活性。