Benzene, 2,3-dichloro-1-methyl-4-(1-methylethyl)- | 81686-44-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Benzene, 2,3-dichloro-1-methyl-4-(1-methylethyl)-
• 英文别名: 2,3-dichloro-1-methyl-4-propan-2-ylbenzene
• CAS: 81686-44-4
• 化学式: C₁₀H₁₂Cl₂
• 分子量: 203.1
• InChiKey: JIWVHJAIMWCERM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-chloro-1-isopropyl-4-methyl-benzene 、 氯 生成 Benzene, 2,3-dichloro-1-methyl-4-(1-methylethyl)-
  参考文献：
  名称：

  KUOKKANEN, TAUNO;AUTIO, PEKKA, CHEMOSPHERE, 18,(1989) N-10, C. 1921-1925

  摘要：

  DOI：

文献信息

• NOVEL PROCESS FOR THE SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-[2-((2R,4R)-4-HYDROXY-6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE
  申请人：——

  公开号：US20020133026A1

  公开（公告）日：2002-09-19

  An improved process for the preparation of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide by a novel synthesis is described where methyl cyanoacetate is converted in eight operations or fewer to the desired product, as well as other valuable intermediates used in the process.

  描述了一种通过新型合成制备5-(4-氟苯基)-1-[2-((2R,4R)-4-羟基-6-氧代-四氢吡喃-2-基)-乙基]-2-异丙基-4-苯基-1H-吡咯烷-3-羧酸苯酰胺的改进工艺，其中将甲基氰乙酸酯在八个或更少的步骤中转化为所需产品，以及在该过程中使用的其他有价值的中间体。
• BISAZOLE-BASED COMPOUND AND GROUP VIII TRANSITION METAL COMPLEX
  申请人：CHI Yun

  公开号：US20130296567A1

  公开（公告）日：2013-11-07

  A bisazole-based compound is represented by formula (I): wherein X represents C—R 3 or nitrogen, R 1 and R 2 independently represent a haloalkyl group, R 3 represents H or F. A transition metal complex is represented by formula (II): ML 1 L 2 L 3 (II) wherein M is a transition metal, L 1 represents in which X represents C—R 31 or nitrogen, R 11 and R 21 independently represent a haloalkyl group, and R 31 represents H or F; and L 2 and L 3 independently represent a dipyridine-based ligand.

  一种基于双咪唑的化合物由式(I)表示：其中X代表C—R3或氮，R1和R2独立地代表卤代烷基，R3代表H或F。一种过渡金属配合物由式(II)表示：ML1L2L3(II)其中M是过渡金属，L1代表其中X代表C—R31或氮，R11和R21独立地代表卤代烷基，而R31代表H或F；L2和L3独立地代表二吡啶基配体。
• ASYMMETRIC UREAS AND MEDICAL USES THEREOF
  申请人：GARCIA RUBIO Silvina

  公开号：US20120220629A1

  公开（公告）日：2012-08-30

  Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I):

  本文披露了一种用于预防和/或治疗由胃饥饿素受体病理生理介导的疾病的化合物、组合物和方法。这些化合物具有一般式(I)。
• [EN] BENZO[1,2-B:4,5-B]FURAN DERIVATIVES AS LIGANDS OF RUTHENIUM DYES AND METHODS FOR OBTAINING THEREOF<br/>[FR] DÉRIVÉS DE BENZO[1,2-B:4,5-B]FURANE À TITRE DE LIGANDS DE COLORANTS AU RUTHÉNIUM ET PROCÉDÉS POUR LES OBTENIR
  申请人：SYNTHEX TECHNOLOGIES SP Z O O

  公开号：WO2016111636A1

  公开（公告）日：2016-07-14

  The present invention relates to a novel ligand for the synthesis of the photosensitizer ruthenium complexes for uses in DSSC, wherein said ligand comprise in their structure benzodifuran moiety bound directly or by a multiple bond with the 2,2'-bipyridine system in positions 4,4' or fluorene system and methods for preparing of said ligand. The subject of the invention is also a new symmetric or asymmetric photosensitizing ruthenium complex for use in DSSC derived from said ligand and methods for preparation of said complex. The resulting complexes have high molar extinction coefficients in the range of visible light and are stable in air environment and after exposure to sunlight, and may be used for the producing of Dye- Sensitized Solar Cells (DSSC). Developed methods are advantageous due to the mild reaction conditions, high repeatability and moderation or high yields.

  本发明涉及一种用于合成光敏剂钌配合物的新型配体，用于DSSC中，其中所述配体在其结构中包含直接或通过多重键与2,2'-联吡啶系统在4,4'位或芴系统结合的苯二呋喃基团，并且用于制备所述配体的方法。本发明的对象还包括一种新的对称或非对称光敏钌配合物，用于DSSC，源自所述配体，并且用于制备所述配合物的方法。所得的配合物在可见光范围内具有高摩尔消光系数，在空气环境中稳定，并且在阳光照射后也稳定，可用于制备染料敏化太阳能电池（DSSC）。由于反应条件温和、重复性高以及产率适中或高，所开发的方法具有优势。
• Remove Amination of 6-Keto Normorphinans by Catalytic Hydrogen Transfer
  申请人：Grote Christopher W.

  公开号：US20100317861A1

  公开（公告）日：2010-12-16

  The present invention provides processes for the stereoselective synthesis of 6-alpha-amino morphinans. In particular, the invention provides processes for the reductive amination of 6-keto normorphinans by catalytic transfer hydrogenation.

  本发明提供了一种用于立体选择性合成6-α-氨基吗啡酮类化合物的方法。具体来说，本发明提供了一种通过催化转移氢化进行6-酮基诺吗啡酮类化合物的还原胺化的方法。