[2,3,3,3-四氟-2-(三氟甲基)丙基]环氧乙烷 | 74328-57-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 中文名称: [2,3,3,3-四氟-2-(三氟甲基)丙基]环氧乙烷
• 英文名称: [(heptafluoroisopropyl)methyl]oxirane
• 英文别名: 3-(perfluoro-1-methylethyl)-1,2-epoxypropane；[2,3,3,3-Tetrafluoro-2-(trifluoromethyl)propyl]oxirane；2-[2,3,3,3-tetrafluoro-2-(trifluoromethyl)propyl]oxirane
• CAS: 74328-57-7
• 化学式: C₆H₅F₇O
• mdl: MFCD00155997
• 分子量: 226.094
• InChiKey: ZCSHSWXXDMBWOP-UHFFFAOYSA-N

物化性质

• 沸点：
  81 °C(lit.)
• 密度：
  0.975 g/mL at 25 °C(lit.)
• 闪点：
  71 °F

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 安全说明：
  S16
• 危险类别码：
  R10
• 海关编码：
  2910900090

反应信息

• 作为反应物：
  描述：

  一氧化碳 、 [2,3,3,3-四氟-2-(三氟甲基)丙基]环氧乙烷 在 [(salph)Cr(THF)2]⁺[Co(CO)4]^- 作用下， 以 乙二醇二甲醚 为溶剂， 25.0 ℃ 、689.49 kPa 条件下， 反应 6.0h， 以86%的产率得到4-(2,3,3,3-tetrafluoro-2-(trifluoromethyl)propyl)-2-propiolactone
  参考文献：
  名称：

  Fluorinated β-lactones and poly(β-hydroxyalkanoate)s: synthesis via epoxide carbonylation and ring-opening polymerization

  摘要：

  Efficient and mild reaction conditions were developed for the catalytic carbonylation of fluorinated epoxides to their corresponding beta-lactones. Six new lactones with fluorinated side chains were prepared in high isolated yields. These lactones were polymerized to form a series of new poly(beta-hydroxy-alkanoate)s with fluorinated side chains, and their properties were examined with respect to their hydrocarbon analogs. Finally, copolymerizations were performed with fluorinated lactones and beta-butyrolactone, which resulted in tapered copolymers rather than the expected random copolymers. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.03.108
• 作为产物：
  描述：

  4-(trifluoromethyl)-4,5,5,5-tetrafluoropent-1-ene 、 间氯过氧苯甲酸 在 碳酸氢钠 、 Sodium sulfate-III 作用下， 以 氯苯 为溶剂， 18.0~133.0 ℃ 、13.51 MPa 条件下， 反应 227.0h， 以to afford about 0.6 gram 2-(2,3,3,3-tetrafluoro-2-(trifluoromethyl)propyl)oxirane product的产率得到[2,3,3,3-四氟-2-(三氟甲基)丙基]环氧乙烷
  参考文献：
  名称：

  Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers

  摘要：

  本发明提供了制备RF（Rτ）nQ等组合物的方法和组合物。其中，RF基团可以包括至少两个—CF3基团，Rτ基团可以是具有至少两个碳的基团，n可以至少为1，而Q基团可以包括元素周期表中的一个或多个原子。本发明还提供了RF中间体（RF（Rτ）nQg）；表面活性剂（RF（Rτ）nQs）；泡沫稳定剂（RF（Rτ）IIQFS）；金属配合物（RF（Rτ）IIQMC）；磷酸酯（RF（Rτ）HQPE）；聚合物（RF（Rτ）IIQMU）；单体（RF（Rτ）IIQM）；脲（RF（Rτ）nQu）；以及/或者乙二醇（RF（Rτ）IIQH）和制备它们的方法。

  公开号：

  US20090137773A1

文献信息

• Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents
  申请人：Novomer, Inc.

  公开号：US20190002400A1

  公开（公告）日：2019-01-03

  The present invention is directed to reactor systems and processes for producing acrylonitrile and acrylonitrile derivatives. In preferred embodiments of the present invention, the processes comprise the following steps: introducing an epoxide reagent and carbon monoxide reagent to at least one reaction vessel through at least one feed stream inlet; contacting the epoxide reagent and carbon monoxide reagent with a carbonylation catalyst to produce a beta-lactone intermediate; polymerizing the beta-lactone intermediate with an initiator in the presence of a metal cation to produce a polylactone product; heating the polylactone product under thermolysis conditions to produce an organic acid product; optionally esterifying the organic acid product to produce one or more ester products; and reacting the organic acid product and/or ester product with an ammonia reagent under ammoxidation conditions to produce an acrylonitrile product.

  本发明涉及反应器系统和生产丙烯腈及丙烯腈衍生物的工艺。在本发明的优选实施例中，该工艺包括以下步骤：将环氧试剂和一氧化碳试剂通过至少一个进料流入口引入至至少一个反应釜中；将环氧试剂和一氧化碳试剂与羰基化催化剂接触以产生β-内酯中间体；在金属阳离子存在下，将β-内酯中间体与引发剂聚合以产生聚内酯产品；在热解条件下加热聚内酯产品以产生有机酸产品；可选择酯化有机酸产品以产生一个或多个酯产品；并将有机酸产品和/或酯产品与氨试剂在氨氧化条件下反应以产生丙烯腈产品。
• Low pressure carbonylation of heterocycles
  申请人：Coates Geoffrey W.

  公开号：US20070213524A1

  公开（公告）日：2007-09-13

  Heterocycles, e.g., epoxides, are carbonylated at low pressure with high percentage conversion to cyclic, ring expanded products using the catalyst where L is tetrahydrofuran (THF).

  杂环化合物，例如环氧化物，在低压下进行羰基化反应，使用催化剂L为四氢呋喃（THF），可高转化率地得到环状、环扩展产物。
• PROCESSES FOR PRODUCING BETA-LACTONE AND BETA-LACTONE DERIVATIVES WITH HETEROGENOUS CATALYSTS
  申请人：Novomer, Inc.

  公开号：US20190047972A1

  公开（公告）日：2019-02-14

  The present invention is directed to processes from producing beta-lactone and beta-lactone derivatives using heterogenous catalysts. In preferred embodiments of the present invention, the processes comprise the steps: passing a feed stream comprising an epoxide reagent and a carbon monoxide reagent to a reaction zone; contacting the epoxide reagent and the carbon monoxide reagent with a heterogenous catalyst to produce a beta-lactone product in the reaction zone; and removing the beta-lactone product from the reaction zone. In preferred embodiments, the heterogenous catalyst comprises a solid support containing a cationic Lewis acid functional group and a metal carbonyl compound comprising at least one of anionic metal carbonyl compound or a neutral metal carbonyl compound. In certain preferred embodiments, the epoxide reagent and carbon monoxide reagent have a biobased content.

  本发明涉及使用异质催化剂生产β-内酯和β-内酯衍生物的过程。在本发明的首选实施例中，该过程包括以下步骤：将包含环氧试剂和一氧化碳试剂的进料流通入反应区；将环氧试剂和一氧化碳试剂与异质催化剂接触，在反应区内产生β-内酯产物；并从反应区中移除β-内酯产物。在首选实施例中，异质催化剂包括固体支撑体，其中包含阳离子路易斯酸功能团和金属羰基化合物，其中至少包括一种阴离子金属羰基化合物或中性金属羰基化合物。在某些首选实施例中，环氧试剂和一氧化碳试剂具有生物基含量。
• Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers
  申请人：Boggs Janet

  公开号：US20070149437A1

  公开（公告）日：2007-06-28

  Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF 3 groups with reactants having cyclic groups. RF compositions such as R F -intermediates, R F -surfactants, R F -monomers, R F- monomer units, R F -metal complexes, R F -phosphate esters, R F -glycols, R F urethanes, and/or R F -foam stabilizers. The R F portion can include at least two —CF 3 groups, at least three —CF 3 groups, and/or at least two —CF 3 groups and at least two —CH 2 — groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the R F -surfactant composition are provided. Acrylics, resins, and polymers are provided that include a R F -monomer unit Compositions are provided that include a substrate having a R F -composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include R F -surfactants and/or R F -foam stabilizers are provided.

  提供生产过程和系统，包括反应卤代化合物，脱卤化合物，反应醇，反应烯烃和饱和化合物，将至少含有两个—CF3基团的反应物与具有环状基团的反应物反应。提供RF组分，例如RF中间体，RF表面活性剂，RF单体，RF单体单元，RF金属络合物，RF磷酸酯，RF乙二醇，RF聚氨酯和/或RF泡沫稳定剂。RF部分可以包括至少两个—CF3基团，至少三个—CF3基团，和/或至少两个—CF3基团和至少两个—CH2—基团。提供包括RF表面活性剂组分的清洁剂，乳化剂，油漆，粘合剂，油墨，润湿剂，发泡剂和消泡剂。提供包括RF单体单元的丙烯酸，树脂和聚合物。提供包括具有RF组分的基底的组合物。提供包括RF表面活性剂和/或RF泡沫稳定剂的水性成膜泡沫（“AFFF”）配方。
• Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams and foam stabilizers
  申请人：Boggs Janet

  公开号：US20070161537A1

  公开（公告）日：2007-07-12

  Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohols, reacting olefins and a saturated compounds, reacting reactants having at least two —CF 3 groups with reactants having cyclic groups. R F -compositions such as R F -intermediates, R F -surfactants, R F monomers, R F -monomer units, R F -metal complexes, R F -phosphate esters, R F -glycols, R F -urethanes, and/or R F -foam stabilizers. The R F portion can include at least two CF 3 groups, at least three —CF 3 groups, and/or at least two —CF 3 groups and at least two —CH 2 — groups. Detergents, emulsifiers, paints, adhesives, inks, wetting agents, foamers, and defoamers including the R F -surfactant composition are provided. Acrylics, resins, and polymers are provided that include a R F -monomer unit. Compositions are provided that include a substrate having a R F -composition thereover. Aqueous Film Forming Foam (“AFFF”) formulations are provided that can include R F surfactants and/or R F -foam stabilizers are provided.

  提供了生产过程和系统，其中包括反应卤代化合物，去卤化化合物，反应醇，反应烯烃和饱和化合物，反应至少有两个—CF3基团的反应物与具有环状基团的反应物反应。提供了RF组分，例如RF中间体，RF表面活性剂，RF单体，RF单体单元，RF金属配合物，RF磷酸酯，RF乙二醇，RF聚氨酯和/或RF泡沫稳定剂。RF部分可以包括至少两个CF3基团，至少三个—CF3基团，以及至少两个—CF3基团和至少两个—CH2—基团。提供了包括RF表面活性剂组分的洗涤剂、乳化剂、油漆、粘合剂、油墨、润湿剂、起泡剂和消泡剂。提供了包括RF单体单元的丙烯酸、树脂和聚合物。提供了包括具有RF组分的基底的组合物。提供了可以包括RF表面活性剂和/或RF泡沫稳定剂的水性成膜泡沫（“AFFF”）配方。