S-(-)-carveol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: S-(-)-carveol
• 英文别名: a (6S)-carveol；(1S)-2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol
• 化学式: C₁₀H₁₆O
• 分子量: 152.236
• InChiKey: BAVONGHXFVOKBV-AXDSSHIGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (+)-反式-柠檬烯 1,2-环氧化物 、 2-氨基苯酚 、 S-(-)-carveol 在 Zinc caprylate 作用下， 反应 1.5h， 以3% carvone was obtained的产率得到香芹酮
  参考文献：
  名称：

  Catalyst system and process for rearrangement of epoxides to allylic alcohols

  摘要：

  一个催化体系，包括一个初级催化剂和一个或多个酚类活化剂/改性剂。初级催化剂可以选择一个或多个均相或非均相的、无机的、有机的或复合的金属化合物。该催化体系可用于通过重排相应环氧化物制备烯丙醇、随后的Oppenauer型氧化反应制备α，β-不饱和羰基化合物，以及通过重排环氧化物制备相应烯丙醇，随后一锅法Oppenauer型氧化反应制备α，β-不饱和羰基化合物。

  公开号：

  US06835686B2
• 作为产物：
  描述：

  香芹酮 在 roots of Manihot dulcis 作用下， 以 水 为溶剂， 反应 72.0h， 以144 mg的产率得到S-(-)-carveol
  参考文献：
  名称：

  Bioreduction of aldehydes and ketones using Manihot species

  摘要：

  Biocatalysis constitutes an important tool in organic synthesis, especially for the preparation of chiral molecules of biological interest. A series of aliphatic and aromatic aldehydes and two ketones were reduced using plant cell preparations from Manihot esculenta and Manihot dulcis roots. The reduced products were typically obtained in excellent yields (80-96%), and with excellent enantiomeric excess (94-98%), except for vanillin. Esters, a nitrile, and an amide were also examined, but were not reduced. Preliminary conversion rate studies are reported. This is the first attempt to perform the biotransformation of carbonyl compounds using Manihot species. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2006.02.008

文献信息

• A Cu-Doped ZIF-8 metal organic framework as a heterogeneous solid catalyst for aerobic oxidation of benzylic hydrocarbons
  作者：Nagarathinam Nagarjun、Amarajothi Dhakshinamoorthy

  DOI：10.1039/c9nj03698a

  日期：——

  Mixed-metal metal organic frameworks have received considerable attention in recent years and it has been shown that the activity of the parent metal organic framework (MOF) is often enhanced upon doping with external metal ions within the framework. In this context, Cu2+ ions with different loadings were incorporated within the ZIF-8 framework to obtain a series of Cu-doped ZIF-8 materials and their

  近年来，混合金属金属有机骨架受到相当大的关注，并且已经表明，在骨架中掺杂外部金属离子后，母体金属有机骨架（MOF）的活性通常会得到增强。在这种情况下，Cu 2+ZIF-8框架中掺入了具有不同负载的离子，以获得一系列掺杂Cu的ZIF-8材料，并在碳氢化合物的好氧氧化中检查了它们的活性。通过粉末X射线衍射（XRD），紫外漫反射光谱（UV-DRS），扫描电子显微镜（SEM），傅立叶变换红外（FT-IR），电子顺磁共振（ EPR）和电感耦合等离子体（ICP）分析。实验结果表明，在120°C下，所有测试基材中掺杂Cu的ZIF-8的活性均远高于其母体ZIF-8的活性。此外，在环辛烷的好氧氧化中，具有最高Cu负载量的Cu掺杂ZIF-8的活性比其母体ZIF-8的活性高八倍（1）在120°C下对相应的环辛醇/环辛酮（ol / one）混合物的选择性超过80％。铜掺杂的ZIF-8被重复使用了两次，在相同条件下
• Bioreduction of aldehydes and ketones using Manihot species
  作者：Luciana L. Machado、João Sammy N. Souza、Marcos Carlos de Mattos、Solange K. Sakata、Geoffrey A. Cordell、Telma L.G. Lemos

  DOI：10.1016/j.phytochem.2006.02.008

  日期：2006.8

  Biocatalysis constitutes an important tool in organic synthesis, especially for the preparation of chiral molecules of biological interest. A series of aliphatic and aromatic aldehydes and two ketones were reduced using plant cell preparations from Manihot esculenta and Manihot dulcis roots. The reduced products were typically obtained in excellent yields (80-96%), and with excellent enantiomeric excess (94-98%), except for vanillin. Esters, a nitrile, and an amide were also examined, but were not reduced. Preliminary conversion rate studies are reported. This is the first attempt to perform the biotransformation of carbonyl compounds using Manihot species. (c) 2006 Elsevier Ltd. All rights reserved.
• Catalyst system and process for rearrangement of epoxides to allylic alcohols
  申请人：——

  公开号：US20030065230A1

  公开（公告）日：2003-04-03

  A catalyst system that can be used to achieve (a) preparation of allylic alcohols by rearrangement of the corresponding epoxide, when the allylic alcohol is a desired product; (b) subsequent reaction, e.g., selective oxidation, of the allylic alcohols obtained in step (a) to afford a desired product, e.g., alpha, beta-unsaturated carbonyl compounds; and/or (c) the ability to perform steps a) and b) in a one-pot process. In one embodiment, the catalyst system includes (i) at least one primary catalyst includes one or more homogeneous or heterogeneous, inorganic, organic or complex metal-containing compound, and (ii) at least one activator/modifier comprising at least one phenolic compound.

  该催化剂系统可用于实现以下目标：(a) 通过重排相应环氧化物制备烯丙醇，当烯丙醇是所需产物时；(b) 后续反应，例如选择性氧化，以获得所需产物，例如α，β-不饱和羰基化合物；和/或(c) 能够在一个反应釜中完成步骤a)和b)。在一种实施例中，该催化剂系统包括：(i) 至少一个初级催化剂，包括一个或多个均相或异相、无机、有机或复合金属化合物，以及(ii) 至少一个活化剂/改性剂，包括至少一个酚类化合物。