1,7-diacetoxy-3-bromoazulene

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 1,7-diacetoxy-3-bromoazulene
• 英文别名: (3-Acetyloxy-1-bromoazulen-5-yl) acetate
• 化学式: C₁₄H₁₁BrO₄
• 分子量: 323.143
• InChiKey: YARYDQOZCNXJHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,3-二碘甘菊蓝 在 吡啶 、 溴 、 溶剂黄146 、 锌 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 1,7-diacetoxy-3-bromoazulene
  参考文献：
  名称：

  Synthesis and Reactivities of 1,5- and 1,7-Azulenequinone Derivatives. A Highly Convenient, One-Pot Synthesis of 3-Bromo-1,5- and −1,7-Azulenequinones by Bromination of Azulene,

  摘要：

  AbstractA very convenient, one‐pot synthesis (over 80% yield) of 3‐bromo‐1,5‐ and −1,7‐azulenequinones has been developed by bromination of azulene in aqueous tetrahydrofuran. Reduction of 3‐bromo‐1,5‐ and −1,7‐azulenequinones with tin or zinc powder in acetic acid gave the parent 1,5‐ and 1,7‐azulenequinones, and further reduction products.

  DOI：

  10.1002/jccs.199800062

文献信息

• Nozoe Tetsuo, Wakabayashi Hidetsugu, Shindo Kimio, Kurihara Teruo, Ishika+, Chem. Lett, (1995) N 1, S 25-26
  作者：Nozoe Tetsuo, Wakabayashi Hidetsugu, Shindo Kimio, Kurihara Teruo, Ishika+

  DOI：——

  日期：——
• Synthesis and Reactivities of 1,5- and 1,7-Azulenequinone Derivatives. A Highly Convenient, One-Pot Synthesis of 3-Bromo-1,5- and −1,7-Azulenequinones by Bromination of Azulene,
  作者：Hidetsugu Wakabayashi、Teruo Kurihara、Kimio Shindo、Masaaki Tsukada、Paw-Wang Yang、Masafumi Yasunami、Tetsuo Nozoe

  DOI：10.1002/jccs.199800062

  日期：1998.6

  AbstractA very convenient, one‐pot synthesis (over 80% yield) of 3‐bromo‐1,5‐ and −1,7‐azulenequinones has been developed by bromination of azulene in aqueous tetrahydrofuran. Reduction of 3‐bromo‐1,5‐ and −1,7‐azulenequinones with tin or zinc powder in acetic acid gave the parent 1,5‐ and 1,7‐azulenequinones, and further reduction products.