chinensioside A

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: chinensioside A
• 英文别名: 3-O-[α-L-Rhap-(1->2)-α-L-Arap]-28-O-[α-L-Rhap-(1->4)-β-D-Glcp-(1->6)-β-D-Glcp]-3β,23-dihydroxylup-20(29)-en-28-oic acid；[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1R,3aS,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-9-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylate
• 化学式: C₅₉H₉₆O₂₆
• 分子量: 1221.4
• InChiKey: OUHBKBTZUPLIIA-WZDJDSACSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  85
• 可旋转键数：
  15
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  413
• 氢给体数：
  15
• 氢受体数：
  26

反应信息

• 作为反应物：
  描述：

  chinensioside A 在 盐酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以6 mg的产率得到23-hydroxybetulinic acid
  参考文献：
  名称：

  摘要：

  Four triterpene glycosides were isolated from the roots of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae). Two new glycosides, chinensiosides A (1a) and B (2), were identified as 3-O-[alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]-3beta,23-dihydroxylup-20(29)-en-28-oic acid and 3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->4)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]-3beta,23-dihydroxylup-20(29)-en-28-oic acid. The other two glycosides were identified as previously known hederasaponin C (3) from Hedera helix and glycoside III (4) from Pulsatilla cernua.

  DOI：

  10.1023/a:1021381308598

文献信息

• ——
  作者：L. I. Glebko、N. P. Krasovskaj、L. I. Strigina、K. P. Ulanova、V. A. Denisenko、P. S. Dmitrenok

  DOI：10.1023/a:1021381308598

  日期：——

  Four triterpene glycosides were isolated from the roots of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae). Two new glycosides, chinensiosides A (1a) and B (2), were identified as 3-O-[alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]-3beta,23-dihydroxylup-20(29)-en-28-oic acid and 3-O-[alpha-L-rhamnopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->4)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]-3beta,23-dihydroxylup-20(29)-en-28-oic acid. The other two glycosides were identified as previously known hederasaponin C (3) from Hedera helix and glycoside III (4) from Pulsatilla cernua.